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Present knowledge in food safety : a risk-based approach through the food chain /

Present Knowledge in Food Safety: A Risk-Based Approach Through the Food Chain presents approaches for exposure-led risk assessment and the management of changes in the chemical, pathogenic microbiological and physical (radioactivity) contamination of 'food' at all key stages of production...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Knowles, Michael E. (Editor), Anelich, Lucia E. (Editor), Boobis, A. R. (Editor), Popping, Bert (Editor)
Format: eBook
Language:English
Published: London, United Kingdom ; San Diego, CA, United States ; Cambridge, MA, United States ; Kidlington, Oxford, United Kingdom : Elsevier, Academic Press, an Imprint of Elsevier, [2023]
Subjects:
Food industry and trade > Safety measures.
Food industry and trade > Risk assessment.
Food > Safety measures.
Food > Risk assessment.
Food science.
Food Safety
Hazard Analysis and Critical Control Points
Food Technology
Aliments > Sécurité > Mesures.
Aliments > Évaluation du risque.
Science des aliments.
Food industry and trade > Safety measures
Food > Safety measures
Food science
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Present Knowledge in Food Safety
  • Copyright Page
  • Dedication
  • Contents
  • List of contributors
  • About the editors
  • Foreword
  • Preface
  • Acknowledgments
  • I. Changes in the chemical composition of food through the various stages of the food chain: plants before harvest
  • 1 Natural toxicants in plant-based foods, including herbs and spices and herbal food supplements, and accompanying risks
  • 1.1 Introduction
  • 1.2 Risk and safety assessment of natural toxins from plants
  • 1.3 Situations where natural toxins from plants may raise concern: Improper food handling [toxic proteins, glycoalkaloids (...
  • 1.3.1 Toxic proteins
  • 1.3.1.1 Toxic proteins: relevant structural features
  • 1.3.1.2 Toxic proteins: toxic mode of action and adverse effects
  • 1.3.1.3 Toxic proteins: risk assessment
  • 1.3.2 Glycoalkaloids
  • 1.3.2.1 Glycoalkaloids: relevant structural features
  • 1.3.2.2 Glycoalkaloids: toxic mode of action and adverse effects
  • 1.3.2.3 Glycoalkaloids: risk assessment
  • 1.3.3 Quinolizidine alkaloids
  • 1.3.3.1 Quinolizidine alkaloids: relevant structural features
  • 1.3.3.2 Quinolizidine alkaloids: toxic mode of action and adverse effects
  • 1.3.3.3 Quinolizidine alkaloids: risk assessment
  • 1.4 Situations where natural toxins from plants may raise concern: Famine food (cyanogenic glycosides, lathyrogens)
  • 1.4.1 Cyanogenic glycosides
  • 1.4.1.1 Cyanogenic glycosides: relevant structural features
  • 1.4.1.2 Cyanogenic glycosides: toxic mode of action and adverse effects
  • 1.4.1.3 Cyanogenic glycosides: risk assessment
  • 1.4.2 Lathyrogens
  • 1.4.2.1 Lathyrogens: relevant structural features
  • 1.4.2.2 Lathyrogens: toxic mode of action and adverse effects
  • 1.4.2.3 Lathyrogens: risk assessment.
  • 1.5 Situations where natural toxins from plants may raise concern: Sensitive individuals (allergens, fava glucosides, and FCs)
  • 1.5.1 Allergens
  • 1.5.2 Fava pyrimidine glycosides
  • 1.5.2.1 Fava pyrimidine glycosides: relevant structural features
  • 1.5.2.2 Fava pyrimidine glycosides: toxic mode of action and adverse effects
  • 1.5.2.3 Fava pyrimidine glycosides: risk assessment
  • 1.5.3 Furocoumarins
  • 1.5.3.1 Furocoumarins: relevant structural features
  • 1.5.3.2 Furocoumarins: toxic mode of action and adverse effects
  • 1.5.3.3 Furocoumarins: risk assessment
  • 1.6 Situations where "normal" dietary intake of natural toxins from plant-based foods may raise concern
  • 1.6.1 Glucosinolates
  • 1.6.1.1 Glucosinolates: relevant structural features
  • 1.6.1.2 Glucosinolates: toxic mode of action and adverse effects
  • 1.6.1.3 Glucosinolates: risk assessment
  • 1.6.2 Alkenylbenzenes including allylalkoxybenzenes and 1-propenylalkoxybenzenes
  • 1.6.2.1 Alkenylbenzenes: structural features
  • 1.6.2.2 Alkenylbenzenes: toxic mode of action and adverse effects
  • 1.6.2.3 Alkenylbenzenes: risk assessment
  • 1.6.3 Pyrrolizidine alkaloids
  • 1.6.3.1 Pyrrolizidine alkaloids: structural features
  • 1.6.3.2 Pyrrolizidine alkaloids: toxic mode of action and adverse effects
  • 1.6.3.3 Pyrrolizidine alkaloids: risk assessment
  • 1.7 Situations where natural toxins from plants may raise concern: Switching varieties [grayanotoxins (GTXs), anisatin, and...
  • 1.7.1 Grayanotoxins
  • 1.7.1.1 Grayanotoxins: structural features
  • 1.7.1.2 Grayanotoxins: toxic mode of action and adverse effects
  • 1.7.1.3 Grayanotoxins: risk assessment
  • 1.7.2 Anisatin
  • 1.7.2.1 Anisatin: structural features
  • 1.7.2.2 Anisatin: toxic mode of action and adverse effects
  • 1.7.2.3 Anisatin: risk assessment
  • 1.7.3 Aristolochic acids
  • 1.7.3.1 Aristolochic acids: structural features.
  • 1.7.3.2 Aristolochic acids: toxic mode of action and adverse effects
  • 1.7.3.3 Aristolochic acids: risk assessment
  • 1.8 Situations where natural toxins from plants may raise concern: Abuse [tropane alkaloids (TAs), opium alkaloids, delta-9...
  • 1.8.1 Tropane alkaloids
  • 1.8.1.1 Tropane alkaloids: structural features
  • 1.8.1.2 Tropane alkaloids: toxic mode of action and adverse effects
  • 1.8.1.3 Tropane alkaloids: risk assessment
  • 1.8.2 Opium alkaloids
  • 1.8.2.1 Opium alkaloids: structural features
  • 1.8.2.2 Opium alkaloids: toxic mode of action and adverse effects
  • 1.8.2.3 Opium alkaloids: risk assessment
  • 1.8.3 Delta-9-tetrahydrocannabinol
  • 1.8.3.1 Tetrahydrocannabinol: structural features
  • 1.8.3.2 Tetrahydrocannabinol: toxic mode of action and adverse effects
  • 1.8.3.3 Tetrahydrocannabinol: risk assessment
  • 1.9 Adulteration with pharmaceutical substances
  • 1.10 Discussion including existing data gaps and research directions
  • References
  • 2 Soil, water, and air: potential contributions of inorganic and organic chemicals
  • 2.1 General introduction
  • 2.2 Heavy metals
  • 2.2.1 Introduction
  • 2.2.2 Sources of heavy metal contamination
  • 2.2.2.1 Air
  • 2.2.2.2 Water
  • 2.2.2.3 Soil
  • 2.2.3 Incidence
  • 2.2.3.1 Air
  • 2.2.3.2 Water
  • 2.2.3.3 Soil
  • 2.2.4 Remediation and preventive measures
  • 2.3 Pesticides
  • 2.3.1 Introduction
  • 2.3.2 Sources of contamination
  • 2.3.2.1 Air
  • 2.3.2.2 Water
  • 2.3.2.3 Soil
  • 2.3.3 Incidence
  • 2.3.3.1 Air
  • 2.3.3.2 Water
  • 2.3.3.3 Soil
  • 2.3.4 Remediation and preventive measures
  • 2.4 Antimicrobials
  • 2.4.1 Introduction
  • 2.4.2 Sources of contamination
  • 2.4.2.1 Air
  • 2.4.2.2 Water
  • 2.4.2.3 Soil
  • 2.4.3 Incidence
  • 2.4.4 Remediation and preventive measures
  • 2.5 Plastics
  • 2.5.1 Introduction
  • 2.5.2 Sources of contamination
  • 2.5.2.1 Air
  • 2.5.2.2 Water
  • 2.5.2.3 Soil.
  • 2.5.3 Incidence
  • 2.5.3.1 Air
  • 2.5.3.2 Water
  • 2.5.3.3 Soil
  • 2.5.4 Remediation and preventive measures
  • 2.6 Other industrial chemicals
  • 2.6.1 Introduction
  • 2.6.2 Sources of contamination
  • 2.6.2.1 Air
  • 2.6.2.2 Water
  • 2.6.2.3 Soil
  • 2.6.3 Incidence
  • 2.6.3.1 Air
  • 2.6.3.2 Water
  • 2.6.3.3 Soil
  • 2.6.4 Remediation and preventive measures
  • 2.7 Uptake of environmental pollutants from air, water, and soil to plant foods
  • 2.8 Human health risk assessment
  • 2.8.1 Introduction
  • 2.8.2 Individual or group health assessments
  • 2.8.2.1 Individual
  • 2.8.2.2 Group
  • 2.8.3 Health risk assessment
  • 2.8.3.1 Acute exposure
  • 2.8.3.2 Long-term exposure
  • References
  • 3 Agrochemicals in the Food Chain
  • 3.1 Introduction
  • 3.2 In vivo metabolism of agrochemicals
  • 3.3 Regulation of agrochemicals
  • 3.4 Agrochemicals commonly found as residues in foodstuffs
  • 3.5 Types of agrochemicals and modes of action
  • 3.5.1 Cleaning/disinfecting agents
  • 3.5.2 Pesticides
  • 3.5.2.1 Neurotoxins
  • 3.5.2.1.1 GABA-gated chloride channel antagonists
  • 3.5.2.1.2 Chloride channel activators
  • 3.5.2.1.3 Sodium channel modulators
  • 3.5.2.1.4 Voltage-dependent sodium channel blockers
  • 3.5.2.1.5 Acetylcholinesterase inhibitors
  • 3.5.2.1.6 Nicotinic acetylcholine receptor agonists
  • 3.5.2.1.7 Nicotinic acetylcholine receptor channel blockers
  • 3.5.2.1.8 Octopamine receptor agonists
  • 3.5.2.1.9 Ryanodine receptor modulators
  • 3.5.2.1.10 Selective feeding blockers-Kir channel inhibition
  • 3.5.2.2 Energy metabolism modulators
  • 3.5.2.2.1 Uncouplers of oxidative phosphorylation
  • 3.5.2.2.2 Mitochondrial complex electron transport inhibitors
  • 3.5.2.3 Insect growth dysregulation
  • 3.5.2.4 Fungicides
  • 3.5.2.4.1 Inhibitors of lipid/steroid/sterol synthesis
  • 3.5.2.4.2 Inhibitors of methionine synthesis
  • 3.5.2.4.3 Multisite action.
  • 3.5.2.5 Herbicides
  • 3.5.2.5.1 Cell walls/growth regulation
  • 3.5.2.5.2 Ripening
  • 3.5.2.5.3 Dysregulation of plant metabolism
  • 3.6 Potential points of concern for agrochemical residues in the food chain
  • 3.6.1 The "cocktail effect"
  • 3.6.2 Endocrine disruption
  • 3.6.3 Effects on the microbiome
  • 3.7 Conclusions and potential areas for further study
  • References
  • 4 Mycotoxins: still with us after all these years
  • 4.1 Introduction
  • 4.2 Compounds of minor public health significance
  • 4.3 Toxins from Fusarium graminearum and related species
  • 4.3.1 Toxins
  • 4.3.2 Management
  • 4.4 Toxins from Fusarium verticillioides and related species
  • 4.4.1 Toxins
  • 4.4.2 Management
  • 4.5 Toxins from Aspergillus flavus, Aspergillus parasiticus, and related species
  • 4.5.1 Management
  • 4.5.2 Toxins
  • 4.6 Ochratoxin-producing Penicillium and Aspergillus species
  • 4.6.1 Management
  • 4.6.2 Toxins
  • 4.7 Key issues for the next decade
  • References
  • II. Changes in the chemical composition of food throughout the various stages of the food chain: animal and milk pro...
  • 5 Occurrence of antibacterial substances and coccidiostats in animal feed
  • Chapter points
  • 5.1 Introduction
  • 5.2 Antibacterial drugs in feed
  • 5.2.1 Antimicrobials in feed
  • 5.2.2 Coccidiostats in feed
  • 5.3 Medicated feed production
  • 5.3.1 Cross-contamination during feed production, transport, and storage
  • 5.3.2 Toxicity to nontarget animal species
  • 5.4 Antimicrobial residues in food derived from animals
  • 5.5 Antimicrobial resistance
  • 5.6 Antimicrobial drugs: impact on the environment
  • 5.7 Analytical methodology
  • 5.8 Research gaps and future directions
  • References
  • 6 Residues relating to the veterinary therapeutic or growth-promoting use and abuse of medicines
  • 6.1 Introduction, general terms, and significance of the topic.