Challenges in Building, Funding, and Conducting a Pragmatic Randomized Controlled Trial of Aspirin for Treating Venous Leg Ulcers /

This case study outlines the pathway to conducting a pragmatic randomized controlled trial to evaluate an over-the-counter drug as an adjuvant to treat venous leg ulceration in the community. We describe the roles of persistence and luck in obtaining funding, the operational challenges of manufactur...

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