Studies toward the total synthesis of apoptolidin : total synthesis of apoptolidinone /

Apoptolidin was isolated by Hayakawa and coworkers in Japan in 1997 from Nocardiopsis sp. and demonstrated the unique biological activity of inducing apoptosis in E1A, E1B oncogene transformed cells but not in normal cells. Khosla and co-workers later discovered that apoptolidin is a mitochondrial...

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Bibliographic Details

Main Author:	Wu, Bin
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 2004.
Subjects:	Major chemistry.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=790270991&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD