Progress towards the total synthesis of apoptolidin /

Apoptolidin (I) was first isolated in 1997 by Hayakawa and co-workers from Nocardiopsis sp. soil bacteria. This polyketide natural product was demonstrated to be a specific apoptosis inducer in cells transformed with the adenovirus type 12 E1A oncogene, but not in normal cells. Chapter I of this...

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Bibliographic Details

Main Author:	Jin, Bohan
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 2002.
Subjects:	Major chemistry.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=764789721&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD