Studies in asymmetric β-lactone synthesis : extensions of the chiral nucleophile catalyzed aldol-lactonization (NCAL) reaction and new transformations of chlorinated β-lactones /

Expansion of Wynberg's procedure for the asymmetric synthesis of β-lactones has been extended to the use of in situ generated ketene. Reaction with dichlorinated aldehydes in the presence of quinidine yielded β-lactone products in good yield (40-85%) and excellent enantioselectivity (93-98% ee...

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Bibliographic Details

Main Author:	Tennyson, Reginald L., 1974-
Format:	Thesis eBook
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 2001.
Subjects:	Major chemistry.
Online Access:	Link to OAKTrust copy