Hormonal regulation of genes involved in purine and pyrimidine biosynthesis and metabolism in human breast cancer cells /

ADA gene expression is induced by E2 in MCF-7 human breast cancer cells, whereas the antiestrogens 4-OH-T and ICI 182,780 exhibit estrogen receptor antagonist activities. In transient transfection studies with pADA211 which contains the -211 to +11 region of the ADA gene promoter linked to CAT rep...

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Bibliographic Details

Main Author:	Xie, Wen, 1969-
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 2001.
Subjects:	Major toxicology.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=728908251&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD