Synthesis and biological evaluation of a bicyclo[7.4.1]enediyne and enantioselective synthesis of 1,2-Aziridinomitosenes /

Naturally occurring enediyne antibiotics possess fascinating structural features, interesting modes of action, and potent antitumor activities. This novel class of antibiotics includes the neocarzinostatin chromophore, [calicheamicin M1] , [esperamicin A,] , and dynemicin A. These molecules have sti...

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Bibliographic Details

Main Author:	Lee, Sangku
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 1998.
Subjects:	Major chemistry.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=732838441&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD