The biology, structure and thermodynamic properties of (CTG)n and (CGG)n trinucleotide repeats from human hereditary diseases /

Since 1991, 12 human loci, responsible for 10 genetic diseases, have been identified in which a normally polymorphic TR undergoes a mutational event where the length of the repeat expands, in some cases, quite dramatically. To understand the underlying molecular mechanism of this expansion, we cond...

Full description

Bibliographic Details

Main Author:	Gellibolian, Robert
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 1996.
Subjects:	Major biochemistry.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=739668961&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD