Studies toward the synthesis of antitumor antibiotics FR-900482 and FR-66979 /

The antitumor antibiotic FR-900482 (1) and FR-66979 (2) were isolated from Streptomyces sandaensis from Fujisawa Pharmaceutical Co. (Japan). FR-900482 (1) and FR-66979 (2) showed potent antitumor activity. This cytotoxicity is apparently related to their ability to induce DNA-DNA and DNA-protein c...

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Bibliographic Details

Main Author:	Lim, Hee-Jong
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 1996.
Subjects:	Major chemistry.
Online Access:	http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=743266761&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD