Mechanism-based inactivation of phosphotriesterase by alkynyl phosphate esters and studies of the amidotransferase activity of E. coli carbamoyl phosphate synthetase /

Alkynyl phosphate esters were used to probe the active site structure of phosphotriesterase. These compounds have the potential to be converted by the enzyme to a highly reactive ketene intermediate which can then react with an active site nucleophile causing irreversible inhibition of the enzyme b...

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Bibliographic Details

Main Author:	Banzon-Kelly, Jennifer Ann, 1966-
Format:	Thesis Book
Language:	English
Published:	[Place of publication not identified] : [publisher not identified] ; 1995.
Subjects:	Major chemistry.
Online Access:	Link to OAKTrust copy http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=742534481&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD