Cover Image

Micro and nano colloids and their biomedical applications /

Micro and Nano Colloids and Their Biomedical Applications offers a comprehensive exploration of the preparation methods, characterization techniques, and real-world applications of micro and nano colloids in the fields of drug delivery, sensory technology, imaging, cosmetics, food preservation, in v...

Full description

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Elaissari, Abdelhamid (Editor), Khizar, Sumera (Editor), Al-Suhaimi, Ebtesam (Editor)
Format: eBook
Language:English
Published: Amsterdam, Netherlands : Elsevier, [2025]
Series:Micro and Nano Technologies
Subjects:
Colloids.
Colloids > Biotechnology.
Colloids in medicine.
Colloïdes en médecine.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • MICRO AND NANO COLLOIDS AND THEIR BIOMEDICAL APPLICATIONS
  • MICRO AND NANO COLLOIDS AND THEIR BIOMEDICAL APPLICATIONS
  • Copyright
  • Contents
  • Contributors
  • Preface
  • 1
  • Colloids: An overview
  • 1.1 Introduction
  • 1.2 Constitution of the colloidal granule
  • 1.3 Classification of colloids
  • 1.3.1 Lyophobic and lyophilic colloids
  • 1.3.2 The eight heterogeneous colloidal systems
  • 1.3.2.1 Simple emulsions and microemulsions
  • 1.3.2.2 Multiple (double) emulsions
  • 1.3.2.3 Pickering emulsions
  • 1.3.2.4 Solid emulsion
  • 1.3.2.5 Sol and solid sol
  • 1.3.2.6 Foams and gels
  • 1.3.2.6.1 Liquid and solid foams
  • 1.3.2.6.2 Gels
  • 1.3.2.7 Liquid and solid aerosols
  • 1.3.2.8 Liposomes, niosomes and transfersomes
  • 1.3.2.8.1 Liposomes
  • 1.3.2.8.2 Niosomes
  • 1.3.2.8.3 Transfersomes
  • 1.4 Preparation methods
  • 1.4.1 Mechanical method
  • 1.4.2 Electro dispersion
  • 1.4.3 Aggregation
  • 1.4.4 Chemical methods for the preparation of colloidal particles
  • 1.5 Methods for colloids characterization
  • 1.6 Physicochemical properties of the colloidal systems
  • 1.6.1 Optical properties
  • 1.6.2 Rheological properties of colloids
  • 1.6.2.1 Viscoelasticity and flow behaviors properties of colloids
  • 1.6.2.2 Storage modulus, G', loss modulus, G"
  • 1.6.2.3 Non-linear viscoelastic behavior of liquid colloids
  • 1.7 Applications of colloids
  • 1.7.1 Colloidal food systems
  • 1.7.2 Medicinal and biomedical applications of colloids
  • 1.7.2.1 Liposomes, polymeric nanospheres, micelles, and oil-in-water emulsions
  • 1.7.2.2 Magnetic colloidal particles
  • 1.7.3 Applications of colloids in wastewater treatment
  • 1.8 Conclusions
  • References
  • 2
  • Basics of magnetic nanoparticles for biomedical applications
  • 2.1 Introduction
  • 2.2 Basics of magnetism
  • 2.2.1 Diamagnetism
  • 2.2.2 Paramagnetism
  • 2.2.3 Ferromagnetism.
  • 2.2.4 Superparamagnetism
  • 2.2.5 Anti-ferromagnetism
  • 2.2.6 Ferrimagnetism
  • 2.3 Synthesis and characterization techniques for magnetic nanoparticles
  • 2.4 Biomedical applications
  • 2.4.1 Magnetic resonance imaging (MRI)
  • 2.4.1.1 Longitudinal magnetization T1
  • 2.4.1.2 Transverse magnetization T2
  • 2.4.2 Hyperthermia
  • 2.4.3 Drug delivery
  • 2.4.4 Magnetic separation
  • 2.5 Conclusion
  • References
  • 3
  • Preparation method: Influence on the properties of colloidal drug delivery systems
  • 3.1 Introduction
  • 3.2 A general view of the methods to prepare colloidal drug delivery carriers
  • 3.3 Operating conditions related to the preparation method and their influence on the physicochemical characteristics of the co ...
  • 3.4 Scaling-up and the study of the influence of the process operating variables on the colloidal carriers' properties
  • 3.5 Conclusions
  • References
  • 4. Colloidal physics and chemistry of nanoparticles
  • 4.1 Introduction
  • 4.2 Particle size and size distribution
  • 4.2.1 Scanning electron microscopy
  • 4.2.2 Transmission electron microscopy
  • 4.2.3 Atomic force microscopy
  • 4.2.4 Dynamic light scattering
  • 4.2.5 Laser diffraction
  • 4.3 Particle shape and morphology
  • 4.4 Interaction of colloidal particles
  • 4.4.1 Potential distribution around a charged surface
  • 4.4.2 Surface charge density
  • 4.4.3 Electrokinetic properties
  • 4.4.4 Surface charge density-zeta potential relationship
  • 4.4.5 Surface charge density and zeta potential measurement
  • 4.4.6 Colloidal stability
  • 4.5 Conclusion
  • References
  • 5
  • Magnetic colloids for isolation, purification, and detection of biomarkers and pathogens in cancer and infectio ...
  • 5.1 Introduction
  • 5.2 Magnetic separation and detection of cancer biomarkers
  • 5.2.1 Nucleic acids
  • 5.2.2 Nucleic acid isolation and purification.
  • 5.2.3 Magnetic separation of nucleic acids (NAs)
  • 5.2.3.1 Magnetic separation by polymer-coated magnetic colloids
  • 5.2.3.2 Magnetic separation by silica-coated magnetic colloids
  • 5.2.3.3 Magnetic separation by affinity-based magnetic colloids
  • 5.2.4 Detection of nucleic acid
  • 5.2.4.1 Optical and fluorescent detection
  • 5.2.4.2 Label-free detection
  • 5.2.4.3 Detection from DNA-Protein mixture
  • 5.2.4.4 Integrated microdevice (microfluidic technique) for DNA and RNA
  • 5.2.5 RNA isolation and detection
  • 5.3 Magnetic separation and purifications of proteins
  • 5.3.1 Metal ion decorated MNPs for protein separation
  • 5.3.2 Silica-coated MNPs for protein separation
  • 5.3.3 Polymer-coated MNPs for protein separation
  • 5.4 MNP-based cell separation and detection
  • 5.4.1 Polymer-coated MNPs for cell separation
  • 5.4.2 Antibody coating/conjugated MNPs
  • 5.4.3 Aptamer-conjugated MNPs for cell separation
  • 5.4.4 Folate receptors conjugated MNPs for cell separation
  • 5.5 MNPs for extracellular vesicles isolation
  • 5.5.1 Stimuli-responsive separation
  • 5.5.2 Magnetic microfluidic separation
  • 5.6 Magnetic-based separation and detection of bacteria and virus
  • 5.6.1 MNPs for bacteria separation and detection
  • 5.6.2 MNPs for virus isolation and detection
  • 5.7 Conclusion and future perspectives
  • Acknowledgments
  • References
  • Further reading
  • 6
  • Advances in imaging-guided nanotheranostics for future personalized therapy
  • 6.1 Introduction
  • 6.2 Imaging modalities
  • 6.2.1 Optical imaging
  • 6.2.2 Magnetic resonance imaging
  • 6.2.3 Nuclear imaging
  • 6.2.4 Computed tomography
  • 6.2.5 Ultrasound
  • 6.3 Nanomaterials
  • 6.3.1 Polymeric based-nanomaterials
  • 6.3.1.1 Polymeric nanoparticles
  • 6.3.1.2 Micelle
  • 6.3.1.3 Dendrimer
  • 6.3.2 Lipid-based nanomaterials
  • 6.3.2.1 Liposomes
  • 6.3.2.2 Solid lipid nanoparticles.
  • 6.3.3 Inorganic nanomaterials
  • 6.3.3.1 Gold nanoparticles
  • 6.3.3.2 Magnetic nanoparticles
  • 6.3.3.3 Silica nanoparticles
  • 6.4 Application of nanotheranostics
  • 6.4.1 Visualizing drug biodistribution
  • 6.4.2 Monitoring and quantification of drug release
  • 6.4.3 Monitoring therapy by imaging
  • 6.4.3.1 Imaging-guided photodynamic therapy
  • 6.4.3.2 Imaging-guided magnetic hyperthermia therapy
  • 6.4.3.3 Imaging-guided photothermal therapy
  • 6.4.3.4 Imaging-guided surgery
  • 6.5 Conclusion
  • References
  • 7
  • An overview of the preparation methods and applications of liposomes. A focus on membrane stability
  • 7.1 Introduction
  • 7.2 Composition and classification
  • 7.3 Methods of preparation
  • 7.3.1 The conventional methods
  • 7.3.1.1 The thin film hydration method
  • 7.3.1.2 The reverse phase evaporation method
  • 7.3.1.3 The solvent injection method
  • 7.3.1.4 The detergent depletion method
  • 7.3.1.5 The emulsion method
  • 7.3.2 Novel methods
  • 7.3.2.1 The freeze-thawing method
  • 7.3.2.2 Freeze-drying or lyophilization
  • 7.3.2.3 The heating method
  • 7.3.2.4 Spray-drying method
  • 7.3.2.5 Membrane contactor technology
  • 7.3.2.6 The microfluidic technology
  • 7.3.2.6.1 The microfluidic techniques generating small and large vesicles
  • 7.3.2.6.2 The microfluidic techniques generating giant vesicles
  • 7.3.2.7 Supercritical fluid technology
  • 7.4 Liposomes as biomimetic model membrane
  • 7.5 Biomedical applications of liposomes: advances and challenges
  • 7.5.1 Liposomes in cancer therapy
  • 7.5.2 Liposomes in gene therapy
  • 7.5.3 Liposomes in vaccines
  • 7.5.4 Liposomes in cosmetics
  • 7.6 Conclusions
  • References
  • 8
  • Recent approaches for cell isolation using micro/nanoparticles
  • 8.1 Introduction
  • 8.2 Methods in cell isolation
  • 8.2.1 Centrifugation techniques
  • 8.2.2 Filtration.
  • 8.2.3 Fluorescence-activated cell sorting (FACS) and microfluidic system
  • 8.2.4 Magnetic-activated cell sorting (MACS)
  • 8.2.5 Microfluidic cell separation
  • 8.2.6 Lab-on-a-chip
  • 8.3 Cell isolation using magnetic nanoparticles (MNPs)
  • 8.3.1 Plain iron oxide nanoparticles
  • 8.3.2 Antibody-functionalized MNPs
  • 8.4 Aptamer-based isolation
  • 8.5 Conclusion and perspectives
  • References
  • 9
  • Recent strategies for microbial detection using bio-conjugate micro/nanoparticles
  • 9.1 Introduction
  • 9.2 The overview of culture-based bacterial detection
  • 9.2.1 Historical perspective and importance
  • 9.2.2 Principles of culture-based bacterial detection
  • 9.2.3 Recent advances and innovations in overcoming limitations of culture-based bacterial detection
  • 9.3 Immunological-based detection of microorganisms
  • 9.3.1 Immunoagglutination assay
  • 9.3.2 Immunofluorescence assay (IFA)
  • 9.3.3 Enzyme-linked immunosorbent assay (ELISA)
  • 9.3.4 Lateral flow immunoassay
  • 9.4 Polymerase chain reaction (PCR)-based detection of microorganisms
  • 9.4.1 Introduction
  • 9.4.2 Principles and integration of bio-conjugate micro/nanoparticles with PCR
  • 9.4.3 Types of bio-conjugate macro/nanoparticles used in microbial detection
  • 9.5 Bioconjugated micro/nanoparticle detection
  • 9.5.1 Physisorption
  • 9.5.2 Adapter molecule
  • 9.5.3 Chemical adsorption
  • 9.5.3.1 Carbodiimide chemistry
  • 9.5.3.2 Maleimide chemistry
  • 9.5.3.3 Click chemistry
  • 9.6 Integrated microscale-based bacteria detection techniques
  • 9.7 Conclusion
  • 9.7.1 Takeaway messages
  • References
  • 10
  • Functional layer-by-layer thin films: From self-assembly to biomedical applications
  • 10.1 Introduction
  • 10.2 Thin films fabrication through layer-by-layer (LBL) approach
  • 10.3 Fabrication of stimuli-responsive multilayer thin films.