Fundamentals of brain organoids for neurological diseases /

Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative di...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Vellingiri, Balachandar (Editor), Balachandar, Mahalaxmi (Editor)
Format: eBook
Language:English
Published: London, U.K. ; Cambridge, MA : Academic Press, [2026]
Subjects:
Online Access:Connect to the full text of this electronic book

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505 0 |a An overview on organoids-- past, present, and future scenarios of organoids / Mahalaxmi Iyer -- A brief introduction to neurodevelopmental disorders / Panimalar Abirami Karuppusamy, Deenathayalan Uvarajan, Masako Kinoshita -- Use of brain organoids for autism / Ajay Elangovan, Nitin Kumar, Tanja Maria Michel -- Role of brain organoids in Rett syndrome / Mohan Gomathi, Pooparambil Vishnupriya -- Brain organoids in bipolar disorder: unraveling mechanisms and therapeutic approaches / Souradip Chaterjee, Laxmi Kirola -- Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders / Bilal Rather, Pragati Kumari, Suryanarayan Biswal -- An overview of neurodegenerative diseases / Sindduja Muthukumar, Harysh Winster Suresh Babu, Mohana Devi Subramaniam -- Use of brain organoids for Parkinson's disease and Alzheimer's diseases / Sneha Kumari, Prajjwal Sharma, Dibbanti HariKrishnaReddy -- Application of brain organoids in Huntington's disease / Roselin Gnanarajan, Nandita Ravichandran, Arul Narayanasamy -- Use of brain organoids for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease, etc.) / Ankit Kumar Bharti S, Deepthi Maria Mathew, Abilash Valsala Gopalakrishnan -- How human-induced pluripotent stem cells are derived into organoids / Harysh Winster Suresh Babu, Nandhini Ilangovan, Ravimanickam Thangarasu -- Elements required and days involved in organoid generation / Vignesh Palanivel, Khushboo Chauhan, Mukesh Kumar Yadav -- Brain organoids - Challenges while constructing organoids / Sudharsan Parthasarathy, Bupesh Giridharan, Longnyu Konyak -- Existing drug targeting and research using brain organoids / Padmanabh Singh, Mayuri Varma, Rakhi Pal -- Ethical considerations while conducting organoids research / Jeyavel Sundaramoorthy, Parthasarathy, Vijyendra Pandey -- Future directions and conclusion / Balachandar Vellingiri, Jyoti Parkash, Mahalaxmi Iyer. 
520 |a Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. This book provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms. 
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