Cerebral Asymmetries /
Cerebral Asymmetries, Volume 208 summarizes research on cerebral hemispheric asymmetries and their implication for consciousness cognition, language emotion, behavior movement, and neurological disease.
| Main Authors: | , |
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| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam, Netherlands :
Elsevier B.V.,
[2025]
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| Edition: | First edition. |
| Series: | Handbook of clinical neurology ;
Volume 208. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Cerebral Asymmetries
- Copyright
- In Memoriam
- Handbook of Clinical Neurology 3rd Series
- Foreword
- Preface
- Contributors
- Contents
- Chapter 1: Cerebral asymmetry: Historical introduction
- Before Broca
- Broca and the Cancel Culture
- The Golden Age of Cortical Localization
- Antilocalizationist Tendencies in Neurology and Psychology
- Lashley and the Coalescence Between Neurology and Psychology
- Donald Hebb and Brenda Milner
- Roger Sperry, the Riddle of the Corpus Callosum and the Split Brain
- References
- Section I: Anatomic asymmetries
- Chapter 2: Asymmetries in the human brain
- Introduction
- Asymmetries From the Cortex to Receptors
- Connectional Anatomy
- Connectional Asymmetries
- Connectional variability
- Commissural pathways
- Corpus callosum
- Anatomical asymmetry
- Interindividual variability
- Anterior commissure
- Anatomical asymmetry
- Interindividual variability
- Association pathways
- Inferior fronto-occipital fasciculus
- Anatomical asymmetry
- Interindividual variability
- Uncinate fasciculus
- Anatomical asymmetry
- Interindividual variability
- Inferior longitudinal fasciculus
- Anatomical asymmetry
- Superior longitudinal fasciculi (SLF I-III)
- Anatomical asymmetry
- Interindividual variability
- Medial occipital longitudinal tract
- Anatomical asymmetry and interindividual variability
- Middle longitudinal fasciculus
- Anatomical asymmetry and interindividual variability
- Arcuate fasciculus (frontotemporal)
- Anatomical asymmetry
- Interindividual variability
- Cingulum
- Anatomical asymmetry
- Interindividual variability
- Vertical systems
- Frontal aslant tract
- Anatomical asymmetry and interindividual variability
- Vertical occipital fasciculus
- Anatomical asymmetry
- Interindividual variability
- Projection pathways
- Fornix.
- Anatomical asymmetry
- Interindividual variability
- Cortico-spinal tract
- Anatomical asymmetry
- Interindividual variability
- Optic radiation
- Anatomical asymmetry
- Interindividual variability
- Thalamic radiations
- Anatomical asymmetry and interindividual variability
- Accumbofrontal tract
- Anatomical asymmetry and interindividual variability
- Fronto-striatal projections
- Anatomical asymmetry and interindividual variability
- Fronto-pontine tract
- U-shaped tracts
- Short frontal tracts
- Fronto-insular tracts (FIT 1-5)
- Anatomical asymmetry
- Interindividual variability
- Frontal longitudinal system (superior and inferior)
- Anatomical asymmetry and interindividual variability
- Fronto-orbito-polar and marginal tract (FOP, FMT)
- Occipital U-shaped tracts
- Parietal U-shaped tracts
- Fronto-parietal U-shaped tracts
- Anatomical asymmetry and interindividual variability
- Conclusion
- Acknowledgments
- References
- Chapter 3: Latent dimensions of brain asymmetry
- Introduction
- Dimensions of Functional Lateralization
- Handedness
- Language lateralization
- Functional laterality beyond handedness and language
- Network analysis of functional laterality
- Dimensions of Structural Asymmetry
- Brain torque
- Global asymmetries beyond brain torque
- Network analysis of structural asymmetry
- Dimensional Associations Between Functional Laterality and Structural Asymmetry
- Concluding Remarks and Future Directions
- References
- Chapter 4: The relationship between brain and visceral asymmetry: Evidence from situs inversus in humans
- Introduction
- Visceral Asymmetry
- Phenotypes of visceral asymmetry
- Situs inversus
- Heterotaxy
- Cause of visceral situs anomalies
- Ontogenesis of visceral asymmetry
- Motile cilia at the primitive node.
- Propagation of the signal to the lateral plate mesoderm and organ primordia
- Brain Asymmetry
- Left-right asymmetry of the neurocognitive system
- Phenotypes of brain functional organization
- Reversed typical functional segregation
- Atypical functional segregation
- Ontogenesis of brain asymmetry
- Neurulation
- Asymmetric development of the central nervous system
- Are asymmetries of visceral and brain development related?
- Atypical Brain Asymmetry in Human Visceral Situs Anomalies
- Systematic review
- Handedness in situs inversus
- Brain functional asymmetry in situs inversus
- Brain structural asymmetry in situs inversus
- Discussion
- References
- Section II: Clinical
- Chapter 5: Oncology: Brain asymmetries in language-relevant brain tumors
- Incidence, Prevalence, and Prognosis of Brain Tumors
- Types of brain tumors
- Brain Tumors and Differences
- Sex differences
- Cognitive difference with left- and right-hemispheric tumors
- Lobar differences
- Techniques to Identify Tumors Affecting the Language System
- Noninvasive structural and functional techniques
- Invasive techniques
- Language and Cognitive Profiles in Brain Tumor Patients
- Gliomas
- Meningiomas
- Supplementary motor area syndrome and spontaneous speech
- Anatomic and Functional Alterations
- White matter dysfunctions and disconnections
- Functional connectivity alterations due to tumor lesions
- Cortical and Subcortical Areas: Functions and Tasks
- Gliomas (awake surgery)
- Meningiomas
- Effect of Surgery on Language/Cognitive Functions
- Glioma (awake procedure)
- Meningioma (asleep procedure)
- Conclusion
- References
- Web References
- Chapter 6: Cerebral asymmetries in schizophrenia
- Introduction
- Schizophrenia
- Cerebral asymmetry in schizophrenia: An historical overview.
- Structural and functional brain asymmetry in schizophrenia
- Air encephalographic studies
- CT scan studies
- Postmortem studies
- Magnetic resonance imaging (MRI) studies
- Cortical areas
- Subcortical structures
- White matter
- Electroencephalography (EEG) studies
- Asymmetry of language structures and implications for symptoms
- Historical framework
- Recent supporting findings: Asymmetry and the genetic load
- The importance of language: An evolutionary perspective
- Disrupted asymmetry and symptoms
- Recent supporting findings: Asymmetry and symptoms
- Conclusions
- References
- Chapter 7: Hemispheric asymmetry in neurodegenerative diseases
- Asymmetry in the AD Spectrum1
- Asymmetry in the FTLD-ALS Spectrum
- The semantic variants
- Nonfluent/agrammatic variant of primary progressive aphasia
- The behavioral variant
- Progressive supranuclear palsy and cortico-basal syndrome
- Amyotrophic lateral sclerosis
- Asymmetry in PD and Lewy Body Disease (LBD)
- Conclusions
- References
- Section III: Consciousness/attention
- Chapter 8: Interhemispheric differences in visual attention
- Introduction
- Alerting
- Orienting
- Studies on brain-damaged patients
- Hemispatial neglect
- Unilateral extinction
- Brain-imaging studies of attention networks
- Cortical centers
- Superior longitudinal fasciculus
- Subcortical attention centers
- Role of the left hemisphere in visuospatial attention
- Effect of multitasking
- Visuospatial bias in chronic left-hemisphere patients
- The role of left and right angular gyrus in visuospatial attention and the Simon effect
- Role of LH in visuospatial memory
- Effects of unilateral cerebellar lesions
- Effects of attention on interhemispheric transfer
- Attention and category-specific cortical areas
- Hemispheric differences in unconscious vs conscious attention.
- Effects of emotion on hemispheric differences in visuospatial attention
- Executive Functions
- Conclusive Remarks
- References
- Chapter 9: Left- and right-side unilateral spatial neglect: Hemispheric differences
- Introduction
- Unilateral spatial neglect in humans
- The history of neglect
- Etiology of neglect
- Rare types of neglect
- The Lateralization of Neglect in Brain-Damaged Animals
- The Lateralization of Neglect in Brain-Damaged Children
- Neglect as a Multicomponent Syndrome
- Defective manifestations
- Sectors of space
- External space
- Internal space
- Spatial reference systems
- Input vs output neural systems
- Extinction to double simultaneous stimulation
- Sensory domains: Visual, tactile, auditory, and olfactory neglect
- Domain specificity
- Anosognosia
- Productive manifestations
- The Assessment of Spatial Neglect
- Peri-personal/near extra-personal space
- Personal space
- Activities of daily living (ADL)
- Test batteries
- Information technology (IT)
- Left vs Right Spatial Neglect
- Overall frequency and severity
- Behavioral similarities and differences between left-side and right-side neglect
- Extra-personal neglect
- Representational neglect
- Input vs output neural systems
- Reference frames
- Contralateral extinction
- Neglect dyslexia, dysgraphia, and dyscalculia
- Anosognosia and personal neglect
- Somatoparaphrenia
- Anatomo-Functional Correlates of Right and Left Spatial Neglect
- Extra-personal neglect
- Damage to the right cerebral hemisphere: Left neglect
- Damage to the left cerebral hemisphere: Right neglect
- Personal neglect
- Damage to the right cerebral hemisphere: Left neglect
- Damage to the left cerebral hemisphere: Right neglect
- Interim conclusion
- Damage to the cerebellum and the brainstem.