Advances in Clinical Chemistry.
Advances in Clinical Chemistry Volume 120, edited by Gregory S. Makowski, explores recent developments in the field of clinical chemistry. This volume features comprehensive reviews on various topics, including congenital disorders of glycosylation (CDG), idiopathic inflammatory myopathies, and the...
| Main Author: | |
|---|---|
| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Chantilly :
Elsevier Science & Technology,
2024.
|
| Edition: | 1st ed. |
| Series: | Issn Series.
|
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Advances in Clinical Chemistry
- Copyright
- Contents
- Contributors
- Preface
- Chapter One: Biochemical diagnosis of congenital disorders of glycosylation
- 1 Introduction
- 2 Fundamentals of glycosylation and related congenital disorders
- 2.1 N-glycosylation
- 2.2 Mucin type O-glycosylation
- 2.3 Glycosaminoglycans synthesis
- 2.4 Congenital disorders of glycosylation (CDG)
- 3 Current CDG biomarkers and related laboratory techniques
- 3.1 Serum transferrin (N-glycosylation) using charge-based techniques
- 3.2 Serum transferrin (N-glycosylation) using mass spectrometry
- 3.3 Total serum/plasma N-glycome analysis after PNGase or EndoH treatment
- 3.4 Other serum N-glycoproteins
- 3.5 Serum apolipoprotein C-III (mucin core1 O-glycosylation)
- 3.6 Cellular CDG biomarkers
- 3.7 Serum bikunin (O-xylosylation of glycosaminoglycans)
- 4 Emerging approaches as sources of new or more informative CDG biomarkers
- 4.1 Implementation of glycoproteomics for protein- and site-specific information
- 4.2 Fucosylated and asialylated mucin core2 O-glycoforms of apoC-III
- 4.3 Metabolomics
- 4.4 Metallomics
- Summary and perspectives
- Acknowledgment
- Appendix A Supporting information
- References