Studies in Natural Products Chemistry /

Studies in Natural Products Chemistry, Volume 85 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts on fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Rahman, Atta-ur-, 1942- (Editor)
Format: eBook
Language:English
Published: Amsterdam, Netherlands : Elsevier Inc., [2025]
Edition:First edition.
Series:Studies in natural products chemistry ; Volume 85.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Studies in Natural Products Chemistry
  • STUDIES IN NATURAL PRODUCTS CHEMISTRY
  • Studies in Natural Products Chemistry: Bioactive Natural Products
  • Copyright
  • Contents
  • Contributors
  • 1
  • Natural product-inspired bioactive alkaloids via C-C/C-N coupling reactions: Synthetic developments, current sc ...
  • Introduction
  • Development of a coupling (C-C/C-N bond) approach: A concise overview
  • Different era of coupling reactions
  • Cross-coupling reactions via a transition metal catalytic approach
  • Cross-coupling reactions via transition metal-free coupling reactions
  • Organocatalytic coupling reaction
  • CDC cross-coupling reaction
  • Oxidant promoted cross-coupling reaction
  • Different classes of bioactive alkaloids and analogues
  • Synthesis of some bioactive alkaloid and alkaloid-based drugs utilizing coupling reactions
  • Oxidative coupling and visible light-mediated photocatalytic addition reactions in the synthesis of bioactive alkaloids
  • Summary
  • Conclusion
  • Abbreviations
  • Authors' contributions
  • Ethics approval
  • Competing interests
  • Acknowledgments
  • References
  • 2
  • Natural product-based drug nanodelivery systems in cancertherapy
  • Introduction
  • Cancer and current conventional treatments in cancer
  • Natural biomolecules investigating in cancer therapy research
  • Curcumin
  • Quercetin
  • Resveratrol
  • Berberine
  • Piperine
  • Thymoquinone
  • Lycopene
  • Genistein
  • Camptothecins
  • Kaempferol
  • Apigenin
  • Ursolic acid
  • Drug delivery systems
  • Organic nanocarriers
  • Lipid-based nanocarriers
  • Liposomes
  • Micelles
  • Solid lipid nanoparticles
  • Protein-based nanocarriers
  • Polysaccharide-based nanocarriers
  • Synthetic polymers
  • Inorganic nanocarriers
  • Biological nanoparticles
  • Exosomes
  • Natural compounds and drug delivery systems in cancer
  • Curcumin
  • Quercetin.
  • Resveratrol
  • Future of nanomedicine and drug delivery system
  • References
  • 3
  • Anticancer activities of coumarins and their structure-activity relationships
  • Introduction
  • General aspects of coumarins
  • Classification of coumarins
  • Simple coumarins
  • The biosynthesis of simple coumarins
  • The distribution of simple coumarins
  • The biological activities of simple coumarins
  • Furanocoumarins
  • The biosynthesis of furanocoumarins
  • The distribution of furanocoumarins
  • The biological activities of furanocoumarins
  • Pyranocoumarins
  • The biosynthesis of pyranocoumarins
  • The distribution of pyranocoumarins
  • The biological activities of pyranocoumarins
  • Coumarin dimers and hybrids
  • The biosynthesis of coumarin dimers
  • The biological activity of coumarin dimers and hybrids
  • Anticancer activities of coumarins
  • Inhibition of tumor angiogenesis
  • Inhibition of microtubule polymerization
  • Effects on apoptosis-related proteins
  • Carbonic anhydrase inhibition effect
  • PI3K/AKT/mTOR pathway inhibition effect
  • Reactive oxygen species regulation
  • Multiple drug resistance inhibition effect
  • Structure-activity relationship studies of coumarins as anticancer agents
  • Conclusion
  • References
  • 4
  • Marine natural products and their anticancer potential via histone deacetylases inhibition in breast cancer
  • Introduction
  • Carcinogenic pathways in breast cancer
  • Marine natural products as breast cancer pathway inhibitors: From sea to life, a chemotherapy perspective
  • Marine natural products and HDAC inhibition
  • Marine natural products and SIRT inhibition
  • Marine natural products and PI3K/AKT inhibition
  • Marine natural products and EGFR receptor inhibition
  • Concluding remarks
  • Abbreviations
  • Acknowledgments
  • References.
  • 5
  • Chitosan-based drug and bioactive delivery systems: Application of chitosan microcapsules to enhance absorption ...
  • Introduction
  • Structure of chitosan microcapsules
  • Preparation of chitosan microcapsules
  • Application of chitosan microcapsules
  • Drug delivery systems
  • Wound dressing/healing
  • Infectious disease prevention
  • Food science applications: Delivering bioactive ingredients
  • Nutrient protection
  • Antimicrobial delivery
  • Antioxidant protection
  • Flavor protection
  • Probiotics microencapsulation
  • Absorption and bioavailability of encapsulated bioactive components
  • Safety assessment of chitosan microcapsules
  • Conclusion
  • References
  • 6
  • A comprehensive review on chemical and phenolic composition and biological activities of Abies species
  • Introduction
  • Genus Abies and usage areas
  • Biological activities
  • Antioxidant activity
  • Antimicrobial activity
  • Other activities
  • Chemical contents
  • Phenolic contents
  • Conclusion
  • Abbreviations
  • References
  • 7
  • Progress in the study of natural grayanane diterpenoids
  • Introduction
  • Biosynthesis and structural types
  • Biosynthesis of GDs
  • Structural types of GDs
  • Subtype A: GDs
  • Subtype B: Seco-GDs
  • Subtype B1: 3,4-seco-GDs
  • Subtype B2: 1,5-seco-GDs
  • Subtype C: Migrate-GDs
  • Subtype D: GD dimers
  • Biological activities of GDs
  • Analgesic activities
  • Antifeedant and insecticidal activity
  • Antiinflammatory activity
  • Other activities
  • Toxicity of GDs
  • Toxicity to animals
  • Toxicity to human
  • Research progress in GDs synthesis
  • Synthesis of grayanotoxin III (1)
  • Synthesis of principinol C (22)
  • Synthesis of pierisformaside C (26)
  • Synthesis of mollanol A (42)
  • Synthesis of leucothol A (49)
  • Synthesis of mollebenzylanol A (50)
  • Conclusion
  • References
  • 8
  • Medicinal value of some horticultural crops.
  • A.R.Ferguson)
  • Pomegranate (Punica granatum L.)
  • Olive (Olea europea L.)
  • Pome fruits
  • Apple (Malus communis Desf.)
  • Rosehip (Rosa canina L.)
  • Wild medlar (Mespilus germanica L.)
  • Stone fruits
  • Apricot (Prunus armeniaca L.)
  • Jackal or blackthorn plum (Prunus spinosa L.)
  • Sweet cherry (Prunus avium L.)
  • Plum (Prunus domestica L.)
  • Nuts
  • Almond (Prunus dulcis D.A.Webb)
  • Hazelnut (Corylus avellana L.)
  • Pistachio (Pistacia vera L.)
  • Walnut (Juglans regia L.)
  • Horticultural plants mostly used as plant-based beverages
  • Tea (Camellia sinensis (L.) Kuntze)
  • Coffee (Coffea arabica L.)
  • Cocoa (Theobroma cacao L.)
  • Some of the most researched and commonly cultivated vegetable species in horticultural crops
  • Garlic (Allium sativum L.)
  • Onion (Allium cepa L.)
  • Mint (Mentha × piperita L.)
  • Parsley (Petroselinum crispum (Mill.) Fuss)
  • Chicory (Cichorium intybus L.)
  • Conclusion
  • References
  • 9
  • Ibervillea sonorae (S. Watson) Green a potential resource of bioactive compounds: Systematic analysis of a Mexi ...
  • Introduction
  • General characteristics and distribution
  • Ethnomedicinal uses
  • Chemical constituents of Ibervillea sonorae
  • Phytosterols and cucurbitacins
  • Phenolics and flavonoids
  • Fatty acids and monoglycerides
  • Simple quantitative and qualitative analysis of chemical constituents
  • Pharmacological properties
  • Effect on cancer cells
  • Extracts and compounds
  • Standardized phytopreparations
  • Hypoglycemic effect
  • Antioxidant activity
  • Antimicrobial activity
  • Antiinflammatory effect
  • Conclusion
  • References
  • Further reading
  • 10
  • The comprehensive role of probiotic-derived peptides in immunomodulation
  • Introduction
  • Targeting the gut microbiome for therapeutic advances
  • The symbiotic relationship: Probiotics and the human immune system.