rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Mitochondria and Neurotoxicity
  name:
    name part: Costa, Lucio G.
    role:
      role term: creator
  name:
    name part: Aschner, Michael.
  name:
    name part: Tieu, Kim.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: xx
    date issued: 2025
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (212 pages).
  abstract: This academic volume examines the role of mitochondria in neurotoxicity, exploring their involvement in environmental and metabolic stress-induced neurological disorders. Contributors analyze mitochondrial dysfunction as both a consequence and driver of neurotoxicity, focusing on mechanisms such as oxidative stress, electron transport chain inhibition, and disruptions in mitochondrial dynamics. The book provides insights into the impact of neurotoxic agents, including pesticides, heavy metals, and solvents, on mitochondrial bioenergetics and proteostasis. It also addresses emerging technologies like high-resolution respirometry and mitochondrial proteomics used to study these phenomena. Intended for researchers, clinicians, and students, this work aims to advance understanding of the mitochondrial role in neurodegenerative diseases such as Parkinson's and the gut-brain axis's link to inflammation caused by mitochondrial toxicants.
  table of contents: Preface -- Introduction to mitochondrial toxicity : form, function, and signaling -- Respirometry parameters as indicators of neurotoxicity -- Pesticide exposure and hippocampal neurogenesis : role of ER stress and mitochondrial dysfunction -- Mitochondrial dysfunction induced by trichloroethylene in Parkinson's disease -- Gut-brain axis and inflammation induced by environmental mitochondrial toxicants -- Mitochondrial toxicants to model Parkinson's disease.
  subject:
    topic: Mitochondria
  subject:
    topic: Environmental toxicology
  subject:
    topic: Mitochondrial pathology
  subject:
    topic: Neurotoxicology
  subject:
    topic: Maladies mitochondriales
  subject:
    topic: Neurotoxicologie
  subject:
    topic: Mitochondrial pathology
  subject:
    topic: Neurotoxicology
  classification: RC347.M57
  classification: 616.80442
  related item:
    title info:
      title: Advances in Neurotoxicology Series
  identifier: 0443240574
  identifier: 9780443240577
  identifier: 0443240566
  identifier: 9780443240560
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: SFB
    record creation date: 250823
    record change date: 20260327191506.6
    record identifier: in00005775998
    language of cataloging:
      language term: eng