Apobec Enzymes.
This book provides a comprehensive exploration of RNA editing, focusing on methodologies, techniques, and assays related to APOBEC enzymes. It includes detailed protocols for fluorescent shift assays, RNA sequencing, purification of APOBEC proteins, and in vitro deamination assays. The book also dis...
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| Format: | eBook |
| Language: | English |
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Chantilly :
Elsevier Science & Technology,
2025.
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| Edition: | 1st ed. |
| Series: | Methods in Enzymology Series.
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book provides a comprehensive exploration of RNA editing, focusing on methodologies, techniques, and assays related to APOBEC enzymes. It includes detailed protocols for fluorescent shift assays, RNA sequencing, purification of APOBEC proteins, and in vitro deamination assays. The book also discusses mutation signatures, genome-wide mutagenic impacts, and profiling rare RNA editing events. Designed for researchers and professionals in biochemistry and molecular biology, the work emphasizes practical applications and aims to advance understanding of genetic editing mechanisms. |
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| Physical Description: | 1 online resource (312 pages). |
| ISBN: | 0443317879 9780443317873 0443317860 9780443317866 |