Circadian rhythms in health and disease /
Circadian Rhythms in Health and Disease, Volume 393 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Circadia...
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| Format: | eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
Academic Press,
2025.
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| Series: | International review of cell and molecular biology ;
volume 393 |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Series Page
- International Review of Cell and Molecular Biology
- Copyright
- Contents
- Contributors
- Preface
- Chapter One: Circuits involving the hypothalamic suprachiasmatic nucleus for controlling diverse physiologies verified by the aid of optogenetics and chemogenetics
- 1 Introduction
- 2 Representative works of SCN optogenetics and chemogenetics
- 3 Conclusions and perspectives
- Acknowledgments
- References
- Chapter Two: Circadian rhythms and cardiac physiology: An essential interplay
- 1 Introduction
- 2 Rhythmic output in the heart
- 3 Impact of circadian disruption on cardiac function
- 4 The circadian clock in cardiac cells
- 4.1 Cardiomyocytes
- 4.2 Endothelial cells
- 4.3 Fibroblasts
- 4.4 Immune cells
- 5 Conclusions and future perspectives
- Sources of funding
- Conflict of interest
- References
- Chapter Three: Circadian rhythms in muscle health and diseases
- 1 Introduction
- 2 Circadian clock machinery
- 2.1 Organisation of the central and peripheral clock
- 2.2 Circadian rhythms in muscle
- 3 Muscle clock in health and diseases
- 3.1 Circadian regulation of muscle maintenance and function
- 3.2 Muscle clock regulation of exercise capacity
- 3.3 Muscle clock function in metabolic health
- 3.4 Muscle clock regulation of protein metabolism
- 3.5 Muscle clock and muscle diseases
- 3.6 Chronotherapy
- 4 Conclusion and perspectives
- Acknowledgements
- Authors contribution
- Conflicts of Interest
- References
- Chapter Four: Emerging interactions between circadian rhythms and extracellular vesicles
- 1 Introduction
- 2 Extracellular vesicles
- 3 Regulation of EVs by circadian clocks
- 4 Circadian regulation of EV number and properties
- 5 Circadian regulation of EV contents
- 6 Functional implications of circadian EV signalling.
- 7 Regulation of circadian clocks by EVs
- 8 Summary and unanswered questions
- Acknowledgements
- References
- Chapter Five: Liver as a nexus of daily metabolic cross talk
- 1 Introduction
- 2 Features of the molecular clock
- 2.1 The core clock mechanism
- 2.2 Clock-controlled output genes
- 2.3 Regulation of clock-controlled output genes in the liver
- 3 The clock from cells to organs and organism
- 3.1 Coupling of clocks in peripheral tissues
- 3.2 Synchrony and coupling within the liver
- 3.3 Relationship between central (brain) and liver clocks
- 4 Temporal cross talk between the liver and other metabolic tissues
- 4.1 Rhythmic metabolism in the liver
- 4.2 Skeletal muscle-liver cross talk
- 4.2.1 Transcription of metabolic pathways
- 4.2.2 Myokines
- 4.2.3 Metabolite exchange
- 4.3 Pancreas-liver cross talk
- 4.4 Intestine-liver cross talk
- 4.4.1 Gut
- 4.4.2 Microbiome
- 4.5 White adipose tissue-liver cross talk
- 5 Circadian metabolism in the context of disease
- 6 Conclusions and future perspectives
- Acknowledgments
- References
- Chapter Six: Non-rhythmic modulators of the circadian system: A new class of circadian modulators
- 1 The circadian oscillator network
- 2 The molecular clockwork
- 3 Temporal coordination across the circadian system
- 4 Non-rhythmic modulators of the circadian system
- 4.1 Rhythms of the hypothalamus-pituitary-thyroid axis
- 4.2 TH tuning of circadian transcriptome rhythms using the liver as an example
- 5 Conclusions
- References
- Back Cover.