Nanotechnology of veterinary medicine and livestock production /
Nanotechnology of Veterinary Medicine and Livestock Production compiles the most impactful emerging research on the use of nanotechnology in animal sciences. This novel data, methods, and technologies will improve animal health, welfare, production, and nutrition, and will have implications for the...
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| Format: | eBook |
| Language: | English |
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London, United Kingdom :
Academic Press,
2025.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Nanotechnology of Veterinary Medicine and Livestock Production
- Copyright Page
- Contents
- About the author
- Preface
- 1 Introduction: historical glimpses and regulations
- 1.1 Introduction
- 1.2 Nanoscience and nanotechnology
- 1.3 Nano
- 1.3.1 Descriptors of nanomaterials
- 1.3.2 Terminology of nanomaterials
- 1.4 Nanotechnology structures
- 1.5 Historical glimpses
- 1.5.1 Prehistoric and ancient civilization
- 1.5.2 Nanomaterials in the modern age
- 1.6 Ultrafine particles versus nanomaterials
- 1.7 Overview of nanomaterial regulation
- 1.7.1 United States of America (USA)
- 1.7.2 European Union
- 1.7.3 United Kingdom (UK)
- 1.7.4 Japan
- 1.7.5 Canada
- 1.7.6 Other countries
- 1.8 Current status
- 1.9 Conclusion
- References
- Further reading
- 2 Sources, synthesis, and classification of nanomaterials
- 2.1 Introduction
- 2.2 Nanoparticles versus larger particles
- 2.3 Sources of nanomaterials
- 2.3.1 Natural
- 2.3.2 Engineered nanomaterials
- 2.4 Classification of nanoparticles
- 2.4.1 Based on dimensions
- 2.4.2 Based on morphology
- 2.4.3 Based on material
- 2.4.4 Based on porosity
- 2.4.5 Other classifications
- 2.5 Nanoclays
- 2.6 Nanoemulsions
- 2.7 Nanocomposites and hybrid nanomaterials
- 2.7.1 Nanocomposites
- 2.7.2 Hybrid NMs
- 2.7.3 Difference between nanocomposites versus hybrid nanomaterials
- 2.8 Nanoelectromechanical systems
- 2.9 Approaches for synthesis of nanomaterials
- 2.9.1 Top-down approach
- 2.9.2 Bottom-up approach
- 2.9.3 Hybrid approaches
- 2.9.4 Other approaches
- 2.9.5 Properties and features of nanomaterials
- 2.9.6 Advantages and disadvantages
- 2.9.7 Characterization of nanoparticles
- 2.10 Current status
- 2.11 Conclusions and future outlook
- References
- Further reading
- 3 Mechanistic approaches to nanoparticles
- 3.1 Introduction.
- 3.2 Factors affecting mechanistic approaches
- 3.2.1 Physicochemical factors
- 3.2.2 Preexposure
- 3.2.3 Environmental factors
- 3.2.4 Other factors
- 3.3 Entry sites, uptake and fate
- 3.4 Elimination pathways for NPs
- 3.5 Cell-NP interactions
- 3.5.1 Dissolution
- 3.6 Extracellular vesicles (EVs) uptake mechanism
- 3.7 Intracellular pathways
- 3.8 Cellular exocytosis
- 3.9 Modes of action of NPs
- 3.9.1 Biocidal mechanisms
- 3.9.1.1 Interaction cell wall and membranes
- 3.9.1.2 Binding to proteins
- 3.9.1.3 Interaction with DNA
- 3.9.1.4 Formation of reactive oxygen species
- 3.9.2 Antioxidant activity
- 3.9.3 Antiinflammatory nanomedicines
- 3.9.4 Immune system modulation
- 3.9.5 Cancer therapy
- 3.9.6 Nanovaccines
- 3.10 Role of surface coating agents
- 3.11 Nanotoxicity
- 3.11.1 Dysfunctions of cellular and Intracellular trafficking
- 3.11.1.1 Inflammation mediated nanotoxicity
- 3.11.1.2 Oxidative stress and nanotoxicity
- 3.11.1.3 Apoptosis and necrosis
- 3.12 Conclusion
- References
- Further reading
- 4 Applications of nanotechnology in animal science
- 4.1 Introduction
- 4.2 Nanoparticles in animal science
- 4.2.1 Categories of nanoparticles
- 4.2.1.1 Metallic/metal-oxide nanoparticles
- 4.2.1.2 Polymeric nanoparticles
- 4.2.1.3 Nanostructured materials
- 4.3 Hybrid nanomaterials for biomedical applications
- 4.3.1 Nanocomposites
- 4.4 Nanoelectromechanical systems
- 4.5 Nanocarriers
- 4.5.1 Nanoencapsulation
- 4.6 Advantages and limitations of nanoparticles
- 4.7 Applications of nanotechnology
- 4.7.1 Nanotechnology in disease diagnostics
- 4.7.2 Pharmaceutics
- 4.7.3 Bovine mastitis
- 4.7.4 Biocides
- 4.7.5 Animal nutrition and feed additives
- 4.7.6 Dairy industry
- 4.7.7 Meat production
- 4.7.8 Nanovaccines
- 4.7.9 Animal reproduction
- 4.7.10 Biosensors.
- 4.7.11 Reproductive biotechnology and cryopreservation
- 4.8 Pros and cons of applications
- 4.9 Current status
- 4.10 Future prospects
- 4.11 Conclusions
- References
- Further reading
- 5 Nanotechnology for antibiotic-based therapies
- 5.1 Introduction
- 5.2 Gram-positive versus Gram-negative bacteria
- 5.3 Use of antibiotics
- 5.3.1 Dairy farming
- 5.3.2 Pigs
- 5.3.3 Poultry
- 5.4 Antibiotic versus nano-antibiotic-based therapies
- 5.5 Antibiotic resistance
- 5.5.1 Sources of antibiotic resistance
- 5.5.2 Biofilm formation
- 5.5.3 Mechanisms of antimicrobial resistance
- 5.5.3.1 Degradation through production of inactivating enzyme
- 5.5.3.2 Decrease in antibiotic uptake
- 5.5.3.3 Activation of alterative metabolic pathways
- 5.5.3.4 Plasmids with antibiotic-resistant genes
- 5.5.3.5 Transferring of resistance genes
- 5.5.3.6 Extrusion of drug outside the cell
- 5.5.3.7 Changes and alterations in antibiotic target
- 5.5.3.8 Biofilm formation
- 5.5.4 Spread of multidrug-resistant and extensively drug-resistant bacteria
- 5.6 Antibiotic-based nanoparticles
- 5.6.1 Inorganic/metal oxide nanoparticles
- 5.6.1.1 Zinc oxide (ZnO)
- 5.6.1.2 Copper (Cu)
- 5.6.1.3 Nickel (Ni)
- 5.6.1.4 Selenium (Se)
- 5.6.1.5 Silver (Ag)
- 5.6.1.6 Gold (AU)
- 5.6.1.7 Silicon (Si)
- 5.6.1.8 Calcium oxide (CaO)
- 5.6.1.9 Magnesium oxide (MgO)
- 5.6.1.10 Iron oxide (IO)
- 5.6.2 Hybrid and organic nanoparticles
- 5.7 Nano carriers
- 5.7.1 Liposomes
- 5.7.2 Solid lipid nanoparticles
- 5.7.3 Polymeric nanoparticles
- 5.7.4 Preparation of nanocarriers
- 5.7.5 Delivery of nanocarriers
- 5.7.6 Endogenous nanocarriers
- 5.8 Antimicrobial growth promoter/feed additives
- 5.9 Synergistic effects of nano antibiotics
- 5.10 Mechanism of action of nano-based antibiotics
- 5.10.1 Synergistic mechanism of action.
- 5.11 Nano-based antibiotic toxicity
- 5.12 Conclusion
- References
- Further reading
- 6 Nanotechnology in livestock nutrition
- 6.1 Introduction
- 6.2 Historical overview
- 6.3 Livestock nutrients
- 6.3.1 Macronutrients
- 6.3.2 Micronutrients
- 6.3.2.1 Minerals
- 6.3.2.2 Manganese (Mn)
- 6.3.2.3 Chromium (Cr)
- 6.3.2.4 Copper (Cu)
- 6.3.2.5 Silver (Ag)
- 6.3.2.6 Iron (Fe)
- 6.3.2.7 Copper (Cu)
- 6.3.2.8 Cobalt (Co)
- 6.3.2.9 Selenium (Se)
- 6.3.2.10 Zinc (Zn)
- 6.3.2.11 Boron (B)
- 6.3.2.12 Vitamins
- 6.4 Bioavailability of nano-micronutrients
- 6.5 Types of nanoparticles
- 6.5.1 Inorganic based
- 6.5.2 Carbon based
- 6.5.3 Organic based
- 6.5.4 Nanoadditives
- 6.5.5 Nanoenzymes
- 6.6 Preparation of nanoscale particles
- 6.6.1 Preparation of enzyme nanoparticles
- 6.6.2 Preparation of nanoadditives
- 6.7 Uptake and delivery of nutrients
- 6.8 Applications in livestock nutrition
- 6.8.1 Ruminants
- 6.8.1.1 Nano-milk production/industry
- 6.8.2 Pigs
- 6.8.3 Poultry
- 6.8.3.1 Growth performance, and improved egg and meat quality
- 6.8.3.2 Antioxidative activity
- 6.8.3.3 Health and immunity
- 6.8.3.4 Pathogenic microbial load
- 6.8.3.5 Nanosensors
- 6.8.3.6 Environment implications
- 6.9 Meat and egg industry
- 6.10 Nanotechnology of vitamins and enzymes
- 6.11 Mode of action
- 6.12 Health and safety concerns
- 6.12.1 Risk evaluation
- 6.12.2 Regulations of nanotechnology
- 6.13 Future prospects
- 6.14 Conclusion
- References
- Further reading
- 7 Nanovaccines in animal health and disease
- 7.1 Introduction
- 7.2 Role of livestock in the global economy
- 7.3 Infectious and noninfectious diseases in animals
- 7.4 Economical importance of infectious diseases
- 7.5 Host-microbe interactions
- 7.6 Adaptation of bacteria
- 7.7 Host-defense mechanisms
- 7.8 Nanovaccine versus traditional vaccines.
- 7.9 Designing nanovaccines
- 7.9.1 Polymer-based systems
- 7.9.1.1 PLGA NPs
- 7.9.1.2 Polyanhydride NPs
- 7.9.1.3 Polysaccharide NPs
- 7.9.2 Lipid-based systems
- 7.9.2.1 Liposomes
- 7.9.2.2 Lipid NPs
- 7.9.2.3 Lipoplexes
- 7.9.3 Inorganic NPs
- 7.9.3.1 Gold (Au) NPs
- 7.9.3.2 Titanium (TiO2) NPs
- 7.9.3.3 Iron oxide (IO) NPs
- 7.9.3.4 Quantum dots (QDs)
- 7.9.3.5 Carbon nanotubes (CNT)
- 7.9.3.6 Silica NPs
- 7.9.4 Hybrid systems
- 7.10 Biomimetic nanovaccines
- 7.10.1 Adjuvants for biomimetic nanovaccines
- 7.10.2 Sources of biomimetic nanovaccines
- 7.10.2.1 Liposomes
- 7.10.2.2 Virus-like NPs (VLPs)
- 7.10.2.3 Self-assembling protein NPs
- 7.10.2.4 Cell membrane-decorated NPs
- 7.10.3 Antigen loading and delivery
- 7.11 Mechanism of actions nanovaccines
- 7.11.1 Activation of innate immunity
- 7.11.2 Activation of adaptive immunity
- 7.11.3 Antibody-mediated immunity
- 7.11.4 Nanovaccine to boost memory
- 7.12 Nanotoxicology of nanovaccines
- 7.13 Conclusions and future perspectives
- References
- Further reading
- 8 Nanotechnology in livestock production
- 8.1 Introduction
- 8.2 Hormonal control in cattle
- 8.2.1 Hormonal control in females
- 8.2.2 Hormonal control in males
- 8.3 Reproductive performance of farm animals
- 8.4 Nanoparticles in livestock production
- 8.4.1 Inorganic nanoparticles
- 8.4.2 Polymeric NPs
- 8.4.3 Lipid- and protein-based NPs
- 8.4.4 Biological (natural)
- 8.4.5 Quantum dots
- 8.4.6 Nanoemulsions
- 8.4.7 Nanobubbles
- 8.4.8 Ceramic nanomaterials
- 8.4.9 Hybrid nanomaterials
- 8.5 Applications in animal production
- 8.6 Nutritional management
- 8.7 Nanotechnology in management of reproduction
- 8.7.1 Tracking estrus
- 8.7.2 Nanopurification of semen
- 8.7.3 Cryopreservation of sperm
- 8.7.4 Reproductive diseases
- 8.7.5 Meat and egg quality
- 8.7.6 Quality of milk.