http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the nervous system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat nervous system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.
Chapter 1. Stem cell-based organoid culture system as an innovative model of the central nervous system development and disease system -- Chapter 2. Applying innovative genome editing technologies (e.g., CRISPR/Cas9 systems) in stem cell engineering and neurological disorders and diseases -- Chapter 3. Role of genetically engineered and modified animal models in investigating neurogenic diseases and disorder -- Chapter 4. Stem cell therapeutics in neurological disorders: classification, mechanisms and clinical applications -- Chapter 5. Emerging trends in stem cell-based treatments for neurodegenerative diseases -- Chapter 6. Derivation and application of haploid neural stem cells in central nervous system disorders and diseases -- Chapter 7. Mesenchymal stem cell-related therapies for neurological diseases and disorders -- Chapter 8. The gold standard induced pluripotent stem cells and induced pluripotent stem cell-derived neural cells in modeling neurological diseases -- Chapter 9. Stem cell innovation in neurological and neurodegenerative disorders: general conclusion, challenges, and prospective -- Index.
volume editors, Mayeen Uddin Khandaker, Mohsin Kazi.
Includes bibliographical references and index.
Stem cell innovation in health and disease ; v. 5