http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Osmolytes and Intrinsically Disordered Proteins
This book explores the functional diversity and significance of intrinsically disordered proteins (IDPs) and their interactions with osmolytes. It delves into the structural and functional modulation of IDPs, highlighting their roles in biological processes, disease pathogenesis, and therapeutic interventions. Specific topics include protein aggregation mechanisms, the therapeutic potential of osmolytes in neurodegenerative diseases such as Parkinson's and Huntington's, and the role of molecular crowding and phase separation in protein dynamics. The text integrates empirical evidence and computational approaches to provide insights into protein behavior and therapeutic strategies. It is intended for researchers, biochemists, and biomedical professionals seeking advanced knowledge in protein science and its applications in disease treatment.
Progress in Molecular Biology and Translational Science Series