Osmolytes and Intrinsically Disordered Proteins.
This book explores the functional diversity and significance of intrinsically disordered proteins (IDPs) and their interactions with osmolytes. It delves into the structural and functional modulation of IDPs, highlighting their roles in biological processes, disease pathogenesis, and therapeutic int...
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
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Chantilly :
Elsevier Science & Technology,
2025.
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| Edition: | 1st ed. |
| Series: | Progress in Molecular Biology and Translational Science Series.
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book explores the functional diversity and significance of intrinsically disordered proteins (IDPs) and their interactions with osmolytes. It delves into the structural and functional modulation of IDPs, highlighting their roles in biological processes, disease pathogenesis, and therapeutic interventions. Specific topics include protein aggregation mechanisms, the therapeutic potential of osmolytes in neurodegenerative diseases such as Parkinson's and Huntington's, and the role of molecular crowding and phase separation in protein dynamics. The text integrates empirical evidence and computational approaches to provide insights into protein behavior and therapeutic strategies. It is intended for researchers, biochemists, and biomedical professionals seeking advanced knowledge in protein science and its applications in disease treatment. |
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| Physical Description: | 1 online resource (332 pages). |
| ISBN: | 9780443293214 044329321X 9780443293207 0443293201 |