ADARs.

This volume focuses on methods and advancements in the study of Adenosine Deaminases Acting on RNA (ADARs), enzymes critical for RNA editing processes. It provides detailed protocols and methodologies for structural and functional analyses, purification techniques, and RNA editing applications in va...

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Bibliographic Details
Main Author: Beal, Peter
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: Chantilly : Elsevier Science & Technology, 2025.
Edition:1st ed.
Series:Methods in Enzymology Series.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:This volume focuses on methods and advancements in the study of Adenosine Deaminases Acting on RNA (ADARs), enzymes critical for RNA editing processes. It provides detailed protocols and methodologies for structural and functional analyses, purification techniques, and RNA editing applications in various biological and medical contexts. The book includes insights into ADAR isoforms, their specificity, and their physiological roles through mouse models. It also discusses advanced sequencing technologies, bioinformatics approaches, and tools for detecting and quantifying RNA editing sites. Aimed at researchers and practitioners in molecular biology, chemistry, and related fields, the text serves as a comprehensive resource for understanding and leveraging ADAR mechanisms in therapeutic and experimental settings.
Physical Description:1 online resource (324 pages).
ISBN:9780443315848
0443315841
9780443315855
044331585X