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20260327181119.1 |
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250217s2025 enk o 001 0 eng d |
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|a OPELS
|b eng
|e rda
|e pn
|c OPELS
|d OCLCO
|d SFB
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|z 9780323955096
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|a (OCoLC)1499871387
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|a QP519.9.I42
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|a 616.07/56
|2 23/eng/20250217
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| 049 |
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|a TXAM
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| 245 |
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|a Handbook of immunoassay technologies :
|b approaches, performances, and applications /
|c edited by Sandeep K. Vashist, John H.T, Luong.
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| 250 |
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|a Second edition.
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| 264 |
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|a London, United Kingdom :
|b Academic Press,
|c 2025.
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 500 |
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|a Includes index.
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|a Online resource; title from PDF title page (ScienceDirect, viewed February 17, 2025).
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|a Front Cover -- Handbook of Immunoassay Technologies -- Copyright Page -- Contents -- List of contributors -- Preface -- Objectives -- Scope -- Target audience -- Book organization -- 1 Immunoassays: an overview -- 1 Overview of immunoassays -- 2 Antibody structure -- 3 Need for immunoassays -- 3.1 Clinical -- 3.2 Industrial -- 3.3 Environment and security -- 3.4 Food -- 3.5 Personalized healthcare -- 4 Immunoassay formats -- 5 Conclusions and future trends -- References -- 2 Antibody immobilization and surface functionalization chemistries for immunodiagnostics -- 1 Introduction -- 2 Surface functionalization chemistries -- 2.1 Hydroxyl groups -- 2.2 Amino groups -- 2.3 Carboxyl groups -- 2.4 Sulfhydryl groups -- 2.5 Epoxy groups -- 3 Antibody immobilization chemistries -- 3.1 Covalent -- 3.2 Oriented -- 3.3 Noncovalent -- Adsorption -- 3.3.1 Affinity -- 3.4 Site-specific -- 3.5 Peptide nucleic acid and deoxyribonucleic acid-directed -- 3.6 Recombinant antibody -- 4 Surface characterization -- 5 Conclusions, challenges, and future trends -- References -- 3 Monoclonal antibody generation by phage display: history, state-of-the-art, and future -- 1 Introduction -- 1.1 History of the development of antibody phage display -- 1.2 Antibody formats used for phage display -- 1.3 Further recombinant antibody formats -- 2 Phage display selection -- 2.1 Advantages of recombinant antibody selection -- 2.2 Guided selection -- 2.3 Affinity improvement -- 2.4 Other selection technologies -- 3 Antibody libraries -- 3.1 Immune libraries -- 3.2 Naive natural libraries -- 3.3 Naive semisynthetic libraries -- 3.4 Naive synthetic libraries -- 3.5 Special library designs -- 3.6 Synthetic libraries from non-human species -- 4 In vitro selection of antibodies for specific applications -- 4.1 Tissue panning for immunohistochemistry antibodies.
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|a 4.2 Sandwich pair selection, complex-specific antibodies, and drug monitoring -- 4.3 Sophisticated guided selection strategies -- 4.4 Fully human controls in diagnostic immunoassays -- 5 Site-specific conjugation and modification of antibody functionality -- 6 Conclusion and outlook -- 6.1 Future -- References -- 4 Bioanalytical requirements and regulatory guidelines for immunoassays -- 1 Introduction -- 2 Bioanalytical requirements for an immunoassay -- 2.1 Accuracy -- 2.2 Precision -- 2.3 Selectivity -- 2.4 Sensitivity -- 2.5 Reproducibility -- 2.6 Stability -- 2.7 Recovery -- 2.8 Calibration curve -- 2.9 Bioanalytical performance parameters -- 2.9.1 Limit of blank -- 2.9.2 Limit of detection -- 2.9.3 Limit of quantification -- 2.9.4 Lower limit of the linear interval -- 2.9.5 Lower limit of the measuring interval -- 2.9.6 Errors -- 2.9.7 Carryover -- 2.9.8 Interference -- 2.9.9 Quality controls -- 2.9.10 Linear range -- 2.9.11 Analytical measurement range -- 2.9.12 Clinically reportable range -- 2.9.13 Bias -- 2.9.14 Hook effect -- 2.9.15 Method comparison -- 2.9.16 Cross-reactivity -- 3 Critiques and outlook -- 4 Conclusions -- References -- 5 Enzyme-linked immunoassays -- 1 Introduction -- 2 Conventional enzyme-linked immunoassays -- 2.1 Enzyme-linked immunosorbent assay -- 2.1.1 Direct ELISA -- 2.1.2 Indirect ELISA -- 2.1.3 Sandwich ELISA -- 2.2 Competitive enzyme-linked immunoassay -- 3 Emerging enzyme-linked immunoassays -- 3.1 High-sensitivity sandwich EIA -- 3.2 Highly simplified rapid sandwich EIA -- 3.3 Wash-free immunoassays -- 3.4 Multiplex immunoassays -- 3.5 Nano-/micro-material-based EIA -- 3.6 Paper-based EIA -- 3.7 Microfluidics-based EIA -- 3.7.1 Optimizer ELISA -- 3.7.2 Centrifugal microfluidics-based IA -- 3.8 Smartphone-based EIA -- 4 Portable analyzer-based immunoassays -- 5 Critiques and outlook -- 6 Conclusions -- References.
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|a 6 Chemiluminescent immunoassays (CLIA) -- 1 Introduction -- 2 Chemiluminescent immunoassay mechanisms -- 2.1 Glow chemiluminescence -- 2.2 Flash chemiluminescence -- 2.3 Electrochemiluminescence -- 3 Commercial chemiluminescence immunoassay analyzers -- 3.1 Closed system -- 3.2 Open system -- 4 Commercial and potential aspects of CLIA -- 5 Conclusions -- References -- 7 Lateral flow immunoassays -- 1 Introduction -- 1.1 Lateral flow immunoassays -- 1.1.1 History of the technology -- 1.1.2 Basic technology -- 1.1.3 Recognition elements -- 1.1.4 Signal labels -- 1.1.5 Storage of lateral flow devices -- 2 Advances in lateral flow immunoassays -- 2.1 Coupling to a range of detection principles -- 2.2 Combination with amplification procedures -- 2.3 Multianalyte lateral flow immunoassays -- 2.4 Reading and quantifying multispot lateral flow assays -- 2.4.1 Lateral flow reader for microarrays-a real-time video reader -- 2.4.2 Reading arrays by smartphone and other applications -- 2.5 Integration of lateral flow immunoassays with paper diagnostics -- 3 Challenges and future directions -- 3.1 Updated SWOT analysis -- 3.2 Bibliographic and commercial data -- 4 Conclusions -- Acknowledgments -- References -- 8 Paper-based immunoassays -- 1 Introduction -- 2 Paper-based immunoassays: strategies and detection principles -- 2.1 Colorimetric method -- 2.1.1 AuNPs -- 2.1.2 Enzymes -- 2.1.3 Carbon nanoparticles -- 2.1.4 Magnetic nanoparticles -- 2.2 Thermal method -- 2.3 Electrochemical method -- 2.4 Magnetic method -- 3 Development of the paper-based immunoassays devices -- 3.1 Sensitivity improvement -- 3.2 Automatic detections -- 3.3 Semiquantification detection and quantification detection -- 4 Conclusions -- References -- 9 Acoustic wave-based immunoassays -- 1 Introduction -- 2 Clinical diagnostics -- 2.1 Quartz crystal microbalance immunosensors.
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|a 2.1.1 Direct immunosensors -- 2.1.2 Indirect immunosensors -- 2.1.3 Sandwich-amplified immunosensors -- 2.2 Surface acoustic wave immunosensors -- 2.2.1 Direct immunosensors -- 3 Detection of microbial pathogens and toxins -- 3.1 Quartz crystal microbalance immunosensors -- 3.1.1 Direct immunosensors -- 3.1.2 Indirect immunosensors -- 3.1.3 Sandwich-amplified immunosensors -- 3.2 Surface acoustic wave immunosensors -- 3.2.1 Direct immunosensors -- 3.2.2 Sandwich-amplified immunosensors -- 4 Detection of parasites -- 4.1 Quartz crystal microbalance immunosensors -- 4.1.1 Direct immunosensors -- 4.1.2 Indirect immunosensors -- 4.1.3 Sandwich-amplified immunosensors -- 5 Detection of viruses -- 5.1 Quartz crystal microbalance immunosensors -- 5.1.1 Direct immunosensors -- 5.1.2 Indirect immunosensors -- 5.1.3 Sandwich-amplified immunosensors -- 5.2 Surface acoustic wave immunosensors -- 6 Quartz crystal microbalance and surface acoustic wave-based electronic noses -- 7 Quartz crystal microbalance and surface acoustic wave immunoassays in environmental monitoring and allergens detection -- 8 Integrated acoustic wave immunosensors for point of care -- 9 Commercial acoustic wave immunosensors -- 10 Market potential and conclusions -- Acknowledgments -- References -- 10 Interferometry-based immunoassays -- 1 Introduction-general context -- 2 Principles of operation -- 2.1 Label-free optical sensing -- 2.2 Interferometric sensors -- 3 Sensor surface functionalization -- 3.1 Chemical activation of transducers -- 3.2 Immobilization of recognition molecules -- 3.3 Elimination of nonspecific binding -- 3.4 Application of interferometric immunosensors -- 3.5 Mach-Zehnder interferometers -- 3.6 Young interferometers -- 3.7 Bimodal interferometers -- 4 Conclusions and future perspectives -- References -- 11 Nanomaterial- and micromaterial-based immunoassays.
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| 505 |
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|a 1 Introduction -- 2 Micromaterial-based immunoassay -- 2.1 Fluorescent polystyrene microsphere -- 2.2 Magnetic microbeads -- 2.3 Nanomaterial-based immunoassay -- 3 Colorimetric immunoassay -- 3.1 Lateral flow assay -- 3.2 Plate-based colorimetric immunoassay -- 4 Electrochemical immunoassay -- 5 Fluorescent immunoassay -- 5.1 Heterogeneous immunoassay -- 5.2 Fluorescence resonance energy transfer assay -- 6 Conclusion -- References -- 12 Microcantilever-based sensors -- 1 Introduction -- 2 Microcantilevers and their modes of operation -- 2.1 Operating modes for cantilever mass sensors -- 3 Detection methods -- 3.1 Optical -- 3.2 Piezoresistive -- 3.3 Capacitive -- 3.4 Piezoelectric -- 3.5 Interferometry -- 3.6 Optical diffraction grating -- 3.7 Charge-coupled device -- 4 Bending behavior of microcantilevers -- 5 Fabrication of microcantilevers -- 6 Microcantilever-based sensors -- 6.1 Detection of biomolecules -- 6.1.1 DNA -- 6.1.2 Prostate-specific antigen -- 6.1.3 Myoglobin -- 6.1.4 Lipoproteins -- 6.1.5 Glucose -- 6.1.6 Tributyrin -- 6.2 Detection of gaseous analytes -- 6.3 Detection of chemicals and metal ions -- 6.4 Detection of humidity and pH -- 6.5 Detection of explosives and monitoring of ammunition -- 7 Electronic nose -- 8 Nanocantilevers -- 9 Commercial availability -- 10 Conclusions and future trends -- References -- 13 Quartz crystal microbalance-based sensors -- 1 Introduction -- 2 Detection of biomolecules -- 3 Detection of bacteria -- 4 Detection of volatile organic compounds -- 5 Detection of chemical analytes -- 6 Detection of gaseous analytes -- 7 Special analytical applications -- 8 Other analytical applications -- 9 Conclusions and future trends -- References -- Further reading -- 14 Electrochemical immunosensors fundamentals and applications in clinical diagnostics -- 1 Introduction.
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| 520 |
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|a Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences.During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats.
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| 650 |
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0 |
|a Immunoassay.
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| 650 |
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6 |
|a Immunodosage.
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| 655 |
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7 |
|a Electronic books.
|2 local
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| 700 |
1 |
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|a Vashist, Sandeep K.,
|e editor.
|
| 700 |
1 |
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|a Luong, John H.T.,
|e editor.
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| 710 |
2 |
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|a ScienceDirect (Online service)
|
| 856 |
4 |
0 |
|u http://proxy.library.tamu.edu/login?url=https://www.sciencedirect.com/science/book/9780323955096
|z Connect to the full text of this electronic book
|t 0
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| 955 |
|
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|a Elsevier ScienceDirect 2026-2027
|
| 994 |
|
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|a 92
|b TXA
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| 999 |
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|t 0
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| 952 |
f |
f |
|a Texas A&M University
|b College Station
|c Electronic Resources
|s www_evans
|d Available Online
|t 0
|e QP519.9.I42
|h Library of Congress classification
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| 998 |
f |
f |
|a QP519.9.I42
|t 0
|l Available Online
|