Polymers for oral drug delivery technologies /
Polymers for Oral Drug Delivery Technologies covers the fundamentals of oral drug delivery and various aspects of polymer technology in oral drug delivery, from classification and synthesis, to applications and regulatory factors. It presents the oral delivery?of therapeutics for treating a number o...
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| Format: | eBook |
| Language: | English |
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Cambridge, MA :
Woodhead Publishing,
[2025]
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| Series: | Woodhead Publishing Series in Biomaterials
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Polymers for Oral Drug Delivery Technologies
- Copyright Page
- Contents
- List of contributors
- Preface
- I. Fundamentals of oral drug delivery
- 1 Gastrointestinal tract environment and its implications on oral drug delivery
- 1.1 Introduction
- 1.2 Overview of the gastrointestinal tract
- 1.3 Key regions of the gastrointestinal tract involved in oral drug delivery and absorption: physiological differences and ...
- 1.3.1 The oral cavity: gateway to the gastrointestinal tract
- 1.3.1.1 Saliva composition and its role in oral drug delivery
- 1.3.1.2 Enzymes in saliva: amylase and its impact on drug delivery
- 1.3.1.3 Other enzymes found in saliva
- 1.3.1.4 pH variations in the oral cavity and their influence on drug absorption
- 1.3.2 Stomach: unraveling its crucial role in drug absorption
- 1.3.2.1 Gastric juice composition and its impact on drug absorption
- Hydrochloric acid
- Pepsin and proteases
- 1.3.2.2 pH variations in the stomach and their implications for drug delivery
- 1.3.3 Intestinal interplay: deciphering the dynamics of drug absorption in small intestine
- 1.3.3.1 Bile salts and their role in absorption
- 1.3.3.2 Enzymatic environment in the small intestine
- Pancreatic enzymes and their role in drug digestion and absorption
- Brush border enzymes and their impact on drug metabolism
- 1.3.3.3 pH variations in the small intestine
- Impact of pH on drug solubility
- Importance of pH and pKa determination
- Henderson-Hasselbalch equation