Pathophysiological aspects of proteases in cancer /

Provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in canc...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Chakraborti, Sajal (Editor), Das, Srijit (Editor), Kim, Cheorl-Ho (Editor)
Format:	eBook
Language:	English
Published:	London, United Kingdom ; San Diego, CA, United States : Academic Press, an imprint of Elsevier, [2025]
Subjects:	Cancer > Pathophysiology. Proteolytic enzymes > Pathophysiology. Proteolytic enzymes. Peptide Hydrolases Enzymes protéolytiques. Enzymes protéolytiques > Physiopathologie. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Chapter 1. Pathophysiological aspects of calpains in cancer
Chapter 2. Mitochondrial proteases in cancer development and progression
Chapter 3. Proteases in head and neck cancer
Chapter 4. Matrix metalloproteinases and uveal melanoma
Chapter 5. Proteases in DNA damage, repair, and radioresistance: Cellular and molecular aspects
Chapter 6. Radiotherapy, proteases and gastric cancer: A complex interplay
Chapter 7. Matrix metalloproteases in the pathogenesis of hepatocarcinoma
Chapter 8. Exploring synthetic and natural compounds for cathepsin B: Mechanisms and therapy
Chapter 9. Kallikrein-related peptidase 3 (KLK3) as valuable biomarkers for prostate cancer
Chapter 10. Ubiquitin specific protease 3,7 in bone cancer and squamous cell carcinoma
Chapter 11. Serine protease: Structure, classification, mechanism and role in breast cancer
Chapter 12. Protease activator receptor-1 and matrix metalloproteinase-1 as prognostic factors and a novel therapeutic targets for gastric cancer
Chapter 13. Matrix metalloproteases as diagnostic and prognostic biomarkers in cancer
Chapter 14. From enzyme to predictors: Serine proteases in cancer diagnosis and prognosis
Chapter 15. Cathepsins as diagnostic and prognostic markers in oral cancer
Chapter 16. Role of kallikreins in prostate cancer
Chapter 17. Mechanistic aspects of serine protease as biomarkers in wound healing of lung cancer
Chapter 18. The role of acetylcholinesterase in cancer development and possible therapeutic applications
Chapter 19. Therapeutics of animal-derived compounds in proteases-induced cancer
Chapter 20. Molecular warriors: Proteases as sentinels in the war against cancer diagnosis and prognosis
Chapter 21. Serine proteases and their contribution to chemoresistance in cancer
Chapter 22. Cathepsins, chemoresistance, and cancer
Chapter 23. Matrix metalloproteinases, chemoresistance and cancer
Chapter 24. MMPs (-2 and -9)-mediated drug resistance and their reversal in gynecological cancer
Chapter 25. The link between trypsinogen and chymotrypsinogen in gastrointestinal cancer
Chapter 26. Role of proteasome in the development of chemoresistance in multiple myeloma
Chapter 27. Role of cysteine cathepsin and matrix metalloproteinases in progression and chemoresistance in ovarian and breast cancer
Chapter 28. Proteases, chemoresistance, and cancer
Chapter 29. Breaking barriers: Proteases as key players in cancer chemoresistance
Chapter 30. Matrix metalloproteases-targeting low-molecular-weight compounds
Chapter 31. Evidence from clinical trials on synthetic protease inhibitors in oral, head, and neck cancer
Chapter 32. Synthetic protease inhibitors in endocrine and gastroenterology cancers: Results of clinical trials
Chapter 33. Side effects of synthetic protease inhibitors used in gynecology cancers
Chapter 34. The role of synthetic protease inhibitors in breast cancer
Chapter 35. Cathepsin-responsive nanomaterials for targeted delivery of malignant tumors.