Advances in microbial physiology. Volume eighty four /
| Corporate Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
London, United Kingdom ; Cambridge, MA ; San Diego, CA :
Academic Press, an imprint of Elsevier,
2024.
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| Edition: | First edition |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Advances in Microbial Physiology
- Copyright
- Contents
- Contributors
- Preface
- Chapter One: New insights in bacterial organophosphorus cycling: From human pathogens to environmental bacteria
- 1 Introduction
- 2 Major forms of organic P found in nature
- 2.1 Phosphoesters
- 2.2 Phospholipids
- 2.3 Phosphonates
- 3 Overview of major organic P transforming enzymes
- 3.1 Enzymes degrading phosphoester (C-O-P) bonds
- 3.2 Enzymes degrading phosphonates (C-P) bonds
- 4 Mechanisms governing the P stress response: advances and open questions
- 5 Organic P transporter systems: new and old
- 5.1 PhoBR-independent secondary active transporters
- 5.2 PhoBR-independent and -dependent primary active transporters
- 6 Recent insights into the mechanism and function of PhoX, PhoA and PhoD
- 6.1 PhoA
- 6.2 PhoX
- 6.3 PhoD
- 6.4 The Pi-irrepressible phosphomonoesterase PafA: a unique P cycling enzyme
- 7 Phospholipid metabolism: mechanisms and consequences for host-microbe interactions
- 7.1 Phospholipase C
- key enzymes in P-lipid hydrolysis
- 7.2 Phospholipase D
- key enzymes in glycerolphosphodiester hydrolysis
- 8 Concluding remarks
- References
- Chapter Two: The formate-hydrogen axis and its impact on the physiology of enterobacterial fermentation
- 1 Introduction
- 2 Key enzyme systems governing intracellular formate levels
- 2.1 Control of formate generation by PflB
- 2.2 How formate regulates H2 production
- 2.3 Formate-oxidising enzymes
- 3 Formate translocation across the cytoplasmic membrane-identification of FocA
- 3.1 FocA is a pentamer
- 3.2 The functional importance of the T91 and H209 residues within FocA's pore
- 3.3 How hypophosphite has provided insight into formate uptake by FocA.
- 6.2.2.1 Extracellular matrix components
- 6.2.3 Quorum sensing: communicating tolerance or new therapeutic targets
- 6.2.4 Validation in vivo
- 6.2.5 Bringing antifungals to the stage
- 6.2.6 Considering viruses and host factors
- 7 New partners in crime
- 7.1 Other natural born antimicrobials
- 7.1.1 Antimicrobial phytochemicals
- 7.1.2 Biosurfactants
- 7.1.3 Bacteriocins
- 7.1.4 Phage therapy
- 7.1.5 Synthetic biology and therapeutic phage products
- 7.1.6 Learning from phage-bacteria interactions
- 7.2 Indirect attackers
- 7.2.1 Targeting the extracellular matrix
- 7.3 Working with the host
- 7.3.1 Monoclonal antibodies
- 7.3.2 Manipulating cytokines and immune cell proliferation
- 7.3.3 Vaccines
- 8 Thinking outside the box
- 8.1 Anti-adherence therapeutics
- 8.2 Anti-type three secretion system therapeutics
- 8.3 Anti-toxin therapeutics
- 9 Perspectives: engagement with industry and clinical partners
- References
- Chapter Five: Protists: Eukaryotic single-celled organisms and the functioning of their organelles
- 1 General introduction
- 2 Motility comparison
- 2.1 Motility of amoebae
- 2.2 Motility of flagellates and ciliates
- 2.3 Gliding motility of the apicomplexa
- 3 Metabolic comparisons
- 3.1 Aerobes
- 3.2 Microaerophiles/anaerobes
- 4 Parasitic protists
- 4.1 Mitochondria and mitochondria-like organelles
- 4.2 Hydrogenosomes
- 4.3 Mitosomes
- 5 Apicoplasts
- 6 Acidocalcisome
- 7 Peroxisomes, glyoxysomes and glycosomes
- 8 Lipid bodies
- 9 GERL (lysosomes, reservosomes, megasomes)
- 10 Micronemes
- 11 Rhoptry
- 12 Dense granules
- 13 Contractile vacuoles
- 14 Cellular differentiation
- 14.1 Encystment (Encystation)
- 14.2 Cyst wall composition
- 14.3 Excystation (excystment)
- 15 Future studies and conclusions
- Acknowledgements
- Dedication
- References
- Back Cover.