Advances in microbial physiology. Volume eighty four /

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Poole, Robert K. (Editor), Kelly, David J. (Editor)
Format: eBook
Language:English
Published: London, United Kingdom ; Cambridge, MA ; San Diego, CA : Academic Press, an imprint of Elsevier, 2024.
Edition:First edition
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Advances in Microbial Physiology
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter One: New insights in bacterial organophosphorus cycling: From human pathogens to environmental bacteria
  • 1 Introduction
  • 2 Major forms of organic P found in nature
  • 2.1 Phosphoesters
  • 2.2 Phospholipids
  • 2.3 Phosphonates
  • 3 Overview of major organic P transforming enzymes
  • 3.1 Enzymes degrading phosphoester (C-O-P) bonds
  • 3.2 Enzymes degrading phosphonates (C-P) bonds
  • 4 Mechanisms governing the P stress response: advances and open questions
  • 5 Organic P transporter systems: new and old
  • 5.1 PhoBR-independent secondary active transporters
  • 5.2 PhoBR-independent and -dependent primary active transporters
  • 6 Recent insights into the mechanism and function of PhoX, PhoA and PhoD
  • 6.1 PhoA
  • 6.2 PhoX
  • 6.3 PhoD
  • 6.4 The Pi-irrepressible phosphomonoesterase PafA: a unique P cycling enzyme
  • 7 Phospholipid metabolism: mechanisms and consequences for host-microbe interactions
  • 7.1 Phospholipase C
  • key enzymes in P-lipid hydrolysis
  • 7.2 Phospholipase D
  • key enzymes in glycerolphosphodiester hydrolysis
  • 8 Concluding remarks
  • References
  • Chapter Two: The formate-hydrogen axis and its impact on the physiology of enterobacterial fermentation
  • 1 Introduction
  • 2 Key enzyme systems governing intracellular formate levels
  • 2.1 Control of formate generation by PflB
  • 2.2 How formate regulates H2 production
  • 2.3 Formate-oxidising enzymes
  • 3 Formate translocation across the cytoplasmic membrane-identification of FocA
  • 3.1 FocA is a pentamer
  • 3.2 The functional importance of the T91 and H209 residues within FocA's pore
  • 3.3 How hypophosphite has provided insight into formate uptake by FocA.
  • 6.2.2.1 Extracellular matrix components
  • 6.2.3 Quorum sensing: communicating tolerance or new therapeutic targets
  • 6.2.4 Validation in vivo
  • 6.2.5 Bringing antifungals to the stage
  • 6.2.6 Considering viruses and host factors
  • 7 New partners in crime
  • 7.1 Other natural born antimicrobials
  • 7.1.1 Antimicrobial phytochemicals
  • 7.1.2 Biosurfactants
  • 7.1.3 Bacteriocins
  • 7.1.4 Phage therapy
  • 7.1.5 Synthetic biology and therapeutic phage products
  • 7.1.6 Learning from phage-bacteria interactions
  • 7.2 Indirect attackers
  • 7.2.1 Targeting the extracellular matrix
  • 7.3 Working with the host
  • 7.3.1 Monoclonal antibodies
  • 7.3.2 Manipulating cytokines and immune cell proliferation
  • 7.3.3 Vaccines
  • 8 Thinking outside the box
  • 8.1 Anti-adherence therapeutics
  • 8.2 Anti-type three secretion system therapeutics
  • 8.3 Anti-toxin therapeutics
  • 9 Perspectives: engagement with industry and clinical partners
  • References
  • Chapter Five: Protists: Eukaryotic single-celled organisms and the functioning of their organelles
  • 1 General introduction
  • 2 Motility comparison
  • 2.1 Motility of amoebae
  • 2.2 Motility of flagellates and ciliates
  • 2.3 Gliding motility of the apicomplexa
  • 3 Metabolic comparisons
  • 3.1 Aerobes
  • 3.2 Microaerophiles/anaerobes
  • 4 Parasitic protists
  • 4.1 Mitochondria and mitochondria-like organelles
  • 4.2 Hydrogenosomes
  • 4.3 Mitosomes
  • 5 Apicoplasts
  • 6 Acidocalcisome
  • 7 Peroxisomes, glyoxysomes and glycosomes
  • 8 Lipid bodies
  • 9 GERL (lysosomes, reservosomes, megasomes)
  • 10 Micronemes
  • 11 Rhoptry
  • 12 Dense granules
  • 13 Contractile vacuoles
  • 14 Cellular differentiation
  • 14.1 Encystment (Encystation)
  • 14.2 Cyst wall composition
  • 14.3 Excystation (excystment)
  • 15 Future studies and conclusions
  • Acknowledgements
  • Dedication
  • References
  • Back Cover.