rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Physics of protein structure and dynamics
    sub title: when and why proteins fold or don't fold
  name:
    name part: Schweitzer-Stenner, Reinhard
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2025
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: Looks at various aspects of protein structure and dynamics from a physico-chemical point of view. It goes into some depth regarding the description of non-covalent forces that determine the relative stability of folded and unfolded proteins. Anharmonic protein dynamics involving motions between different minima of a rugged Gibbs energy landscape is described in great detail. The book combines various aspects of the protein folding/unfolding processes with an overview of intrinsically disordered proteins, which have attracted considerable interest of the protein community over the last 25 years but are thus far underrepresented in classroom-oriented textbooks. The book looks at protein folding and intrinsically disordered proteins as heavily interrelated topics that need to be viewed together. Furthermore, it presents some basic physico-chemical aspects of protein/peptide self-assembly into nanoscale fibrils. Intrinsically disordered peptides and proteins play a major role particularly in aggregation and self-assembly processes that lead to various diseases (Alzheimer, Parkinson, Huntington, Mad-Cow). Therefore, the relevance of protein disorder for protein self-assembly deserves a closer look. Protein self-assembly cannot be separated from protein folding since it is frequently the product of misfolding. With regard to modern theories, the folding processes are linked to insights on protein dynamics and the discovered relationship between proteins and spin glasses.
  table of contents: 4.5 Characterizing the conformational ensembles of intrinsically disordered proteins -- 4.6 Orderdisorder and disorderdisorder transitions -- 4.7 Topics for discussion -- 4.8 Problems -- References -- 5 Protein and peptide self-assembly -- 5.1 Introduction -- 5.2 Amyloid structure and underlying forces -- 5.3 Kinetics of amyloid formation -- 5.4 Liquid-liquid demixing -- 5.5 Outlook -- 5.6 Topics of discussion -- 5.7 Problems -- References -- 6 Summary and outlook -- References -- Index -- Back Cover.
  note: Reinhard Schweitzer-Stenner.
  note: Includes bibliographical references and index.
  subject:
    topic: Protein folding
  subject:
    topic: Self-assembly (Chemistry)
  subject:
    topic: Protéines
    topic: Repliement
  subject:
    topic: Autoassemblage
  classification: QP551 .S39 2025
  classification: 572/.633
  related item:
    identifier: (OCoLC)1419058179
  identifier: 9780443159657
  identifier: 0443159653
  identifier: 9780443159640
  identifier: 0443159645
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: YDX
    record creation date: 240929
    record change date: 20260327180334.7
    record identifier: in00005773743
    language of cataloging:
      language term: eng