rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Neurologic channelopathies
  name:
    name part: Hanna, Michael G.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    publisher: Elsevier
    date issued: 2024
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies.Ion.
  table of contents: Intro -- Neurologic Channelopathies -- Copyright -- Handbook of Clinical Neurology 3rd Series -- Foreword -- Preface -- Genetic and autoimmune mechanisms -- Common pathophysiologic themes across muscle, nerve, and the brain -- Genomic sequencing for precision diagnostics and the challenge of variants of uncertain significance in ion channel genes -- This Volume -- Contributors -- Contents -- Chapter 1: Structure-function and pharmacologic aspects of ion channels relevant to neurologic channelopathies -- Introduction -- Classification of Ion Channels -- Genetics -- Structure-Function
  table of contents: Tetrameric potassium channels -- Inward rectifying potassium channels -- Tandem pore domain potassium channels -- Voltage-gated potassium channels -- Transient receptor potential channels -- Voltage-gated sodium and calcium channels -- Voltage-gated chloride channels -- Ligand-gated channels -- Pentameric ligand-gated ion channels (Cys-loop channels) -- Ionotropic glutamate receptors -- Trimeric channels -- Pharmacology -- References -- Chapter 2: Inherited myotonias -- Introduction -- Clinical Features -- Myotonia congenita -- Paramyotonia congenita and sodium channel myotonia
  table of contents: Myotonic dystrophies -- Life course of inherited myotonias -- Pathophysiology -- Myotonia congenita -- Myotonic dystrophy -- Paramyotonia congenita and sodium channel myotonia -- Diagnostic Approach -- Clinical evaluation -- Neurophysiology -- Imaging and histology -- Functional genetics -- Treatment and Management Approach -- Lifestyle measures -- Pharmacotherapy -- Pregnancy and anesthesia -- Conclusion -- References -- Chapter 3: Periodic paralysis -- Introduction -- Clinical presentation -- Shared pathomechanism for episodic weakness in all forms of periodic paralysis
  table of contents: Clinical spectrum of nondystrophic myotonia and periodic paralysis -- Approaches to diagnosis in periodic paralysis -- Overview of therapeutic intervention in periodic paralysis -- Hypokalemic Periodic Paralysis -- Clinical features and diagnosis (HypoPP) -- Ion channel mutations and pathophysiology (HypoPP) -- Investigational approaches for pharmacologic management of episodic weakness (HypoPP) -- HyperPP/PMC -- Clinical features and diagnosis (HyperPP/PMC) -- Ion channel mutations and pathophysiology (HyperPP/PMC) -- Andersen Tawil Syndrome -- Thyrotoxic Periodic Paralysis
  table of contents: Clinical features and diagnosis (TPP) -- Ion channel mutations (TPP) -- Rare Variants of Atypical Periodic Paralysis -- Myopathy and myasthenic syndromes with recessive SCN4A variants -- Ryanodine receptor-associated atypical periodic paralysis -- Na/K-ATPase associated periodic paralysis plus seizures -- Conclusions -- Acknowledgments -- References -- Chapter 4: Andersen-Tawil syndrome -- Introduction -- Epidemiology -- Relation to Other Periodic Paralyzes -- Clinical Manifestations: Weakness -- Clinical Manifestations: Cardiac Arrhythmias -- Clinical Manifestations: Physical Dysmorphisms
  note: edited by Michael G. Hanna.
  subject:
    topic: Neurology
  subject:
    topic: Nervous system
    topic: Diseases
  subject:
    topic: Neurology
  subject:
    topic: Nervous System Diseases
  subject:
    topic: Neurologie
  subject:
    topic: Système nerveux
    topic: Maladies
  classification: RC346
  classification: 616.8
  related item:
    title info:
      title: Handbook of clinical neurology ; v. 203
  related item:
    identifier: (OCoLC)1410860962
  identifier: 9780323908214
  identifier: 0323908217
  identifier: 9780323908207
  identifier: 0323908209
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: YDX
    record creation date: 240825
    record change date: 20260327180331.8
    record identifier: in00005773705
    language of cataloging:
      language term: eng