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Diagnostic, prognostic, and therapeutic role of MicroRNAs in head and neck cancer /

Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSC...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Kumar, Ashok (Editor), Arya, Neha (Editor), Tiwari, Shikha (Editor), Khan, Raju (Editor)
Format: eBook
Language:English
Published: London, United Kingdom : Academic Press, 2024.
Subjects:
MicroRNA.
Head > Cancer > Genetic aspects.
Head > Cancer > Diagnosis.
Neck > Cancer > Genetic aspects.
Neck > Cancer > Diagnosis.
MicroRNAs
MicroARN.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer
  • Copyright Page
  • Contents
  • List of contributors
  • 1 Epidemiology, pathology, and genomic topography of head and neck cancers
  • 1.1 Introduction
  • 1.2 Epidemiology of head and neck cancer
  • 1.3 Risk factors
  • 1.3.1 Tobacco
  • 1.3.2 Alcohol
  • 1.3.3 Human papillomavirus
  • 1.4 Squamous cell carcinoma
  • 1.4.1 Precursors
  • 1.4.1.1 Leukoplakia
  • 1.4.1.2 Erythroplakia
  • 1.4.1.3 Squamous dysplasia
  • 1.4.1.4 Proliferative verrucous leukoplakia
  • 1.4.2 Histologic variant
  • 1.4.2.1 Verrucous squamous cell carcinoma
  • 1.4.2.2 Basaloid squamous cell carcinoma
  • 1.4.2.3 Spindle cell squamous cell carcinoma
  • 1.5 Genetic landscape of head and neck cancer
  • 1.5.1 Comprehensive genetic analysis of head and neck squamous cell carcinoma
  • 1.5.2 Mutations
  • 1.5.3 Copy number alterations
  • 1.6 Signaling pathway associated with head and neck squamous cell carcinoma
  • 1.6.1 Epidermal growth factor receptor pathway
  • 1.6.2 Mitogen-activating protein kinase pathway
  • 1.6.3 Phosphoinositide 3-kinase/Ak strain transforming/Mammalian target of rapamycin pathway
  • 2 Association of human papillomavirus with head and neck cancers
  • 2.1 Head and neck cancers: pathogenesis, incidence, and mortality
  • 2.2 Risk factors for head and neck cancers
  • 2.3 Human papillomavirus: history, genome, and mode of infection
  • 2.3.1 Mechanisms associated with human papillomavirus-induced oncogenesis
  • 2.4 Epidemiology and regional differences in incidence of human papillomavirus-positive head and neck cancer
  • 2.4.1 Determination of human papillomavirus status
  • 2.5 Differences in mutational signatures between human papillomavirus-positive and human papillomavirus-negative head and n...
  • 2.6 Clinical implications of human papillomavirus positivity in head and neck cancers
  • 2.7 Conclusion
  • References
  • 3 MicroRNA regulation of different subtypes of head and neck malignancies
  • 3.1 Introduction
  • 3.2 MicroRNAs: biogenesis and role in cancer
  • 3.3 miRNA regulation of head and neck malignancies
  • 3.4 Role of miRNAs in different subtypes of head and neck malignancies
  • 3.4.1 Oropharyngeal cancer
  • 3.4.2 Hypopharyngeal cancer