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Omega-3 fatty acids : a scientific approach to healthy aging and optimized nutrition /

Omega-3 Fatty Acids: A Scientific Approach to Healthy Ageing and Optimized Nutrition looks at the biochemistry of long chain fatty acids and their importance to health, well-being, and the reduction of inflammation in the body. Divided into two parts, the book first explains the history, chemical ba...

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Bibliographic Details
Main Author: Lembke, Peter (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: London, United Kingdom ; San Diego, CA : Academic Press, [2025]
Subjects:
Omega-3 fatty acids.
Acides gras oméga 3.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Omega-3 Fatty Acids
  • Omega-3 Fatty Acids: A Scientific Approach to Healthy Aging and Optimized Nutrition
  • Copyright
  • Contents
  • Foreword
  • List of abbreviations
  • One
  • Introduction-Why the inclusion of dietary omega-3 fatty acids allowed the development of Homo sapiens and sti ...
  • References
  • Two
  • Lipids, fats, and oils
  • 2.1 History
  • 2.2 Fats and oils
  • 2.3 Dietary lipids and their classification
  • 2.3.1 Fatty acids
  • 2.3.1.1 Saturated and unsaturated fatty acids
  • 2.3.1.2 Monounsaturated fatty acids (with one double bond)
  • 2.3.1.3 Polyunsaturated fatty acids (with more than one double bond)
  • 2.3.2 Triglycerides
  • 2.3.2.1 Triglycerides (TGs) versus ethyl esters (EEs)?
  • 2.4 Sources of omega-3 EPA and DHA
  • References
  • Three
  • Bioavailability
  • 3.1 Lipid digestion and absorption
  • 3.2 Relative Bioavailability Index for EEs, FFAs, TGs, and rTGs
  • References
  • Four
  • Metabolic routes for fatty acids
  • 4.1 Reaching the site of beta-oxidation
  • 4.2 Inclusion into tissue cell membrane
  • 4.3 Important derivates from EPA and DHA
  • 4.3.1 Prostaglandins, resolvins, protectins, and maresins
  • 4.3.1.1 Prostaglandin-E1 (PGE-1)
  • 4.3.1.2 Prostaglandin-E2 (PGE-2)
  • 4.3.1.3 Prostaglandin-E3 (PGE-3)
  • 4.3.1.4 Resolvins, protectins, and maresins
  • References
  • Five
  • Creating anti-inflammatory synergies with EPA/DHA
  • 5.1 Simplified model of the inflammatory response process
  • 5.2 Combination of EPA and DHA with omega-6 GLA
  • 5.3 Combination of EPA and DHA with aspirin
  • References
  • Six
  • Essential fatty acids and the importance of a balanced omega-6-to-omega-3 ratio in our diet
  • References
  • Seven
  • Vegetable-versus animal omega-3
  • 7.1 Vegetable omega-3
  • 7.1.1 Alpha-linolenic acid (ALA)
  • 7.1.2 Stearidonic acid (SDA)
  • 7.2 Animal omega-3s.
  • 7.2.1 Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
  • 7.2.1.1 EPA versus DHA
  • 7.2.2 DPA-Greenland seal oil
  • 7.2.3 Eicosatetraenoic acid (ETA)
  • 7.2.4 Krill oil-EPA and DHA in phospholipid form
  • References
  • Eight
  • Omega-3 dietary supplements versus omega-3 enriched food
  • 8.1 Fish oil capsules versus omega-3 concentrates
  • 8.2 Omega-3 enriched foods
  • Reference
  • Nine
  • Approved health claims, recommended daily intakes, and safety
  • 9.1 FDA-Food and drug administration (USA)
  • 9.1.1 Safety
  • 9.1.2 Qualified health claims
  • 9.1.3 Nutrient content claims
  • 9.2 EFSA-European Food Safety Authority (EU)
  • 9.2.1 Safety
  • 9.2.2 Qualified health claims
  • 9.2.3 Nutrient content claims
  • 9.3 Other authorities or associations
  • 9.4 Safety of omega-3
  • References
  • Ten
  • Fish oil and omega-3 concentrate production and PUFA-oxidation control
  • 10.1 Fish oil and omega-3 concentrate production
  • 10.2 Oxidation of polyunsaturated fatty acids (PUFAs)
  • References
  • Eleven
  • Reading and understanding the label
  • 11.1 How long should you take omega-3s?
  • 11.2 Do I need more EPA or more DHA?
  • 11.3 Read and understand the label
  • Twelve
  • Healthy aging with omega-3's
  • 12.1 What is aging?
  • 12.2 The omega-6 to omega-3 ratio in our diet, senior health, and longevity
  • References
  • Thirteen
  • How to determine your individual daily omega-3 dose and to distinguish between primary and secondary ris ...
  • 13.1 The "omega-6 status"
  • 13.2 The omega-3 index
  • 13.3 Primary- and secondary health risk factors
  • References
  • Fourteen
  • Cardiovascular health and Omega-3s
  • 14.1 Sudden cardiac death
  • 14.2 Stress and sudden cardiac death
  • 14.3 Heart failure
  • 14.4 Heart attack/heart infarct
  • 14.4.1 Arteriosclerosis and the heart-attack-model
  • 14.4.2 Cholesterol and hypercholesterolemia.
  • 14.4.2.1 Is cholesterol a good cardiovascular risk factor?
  • 14.4.2.2 Understanding blood cholesterol
  • 14.4.2.3 Does DHA increase blood LDL-cholesterol?
  • 14.5 Hypertriglyceridemia/dyslipidemia
  • 14.6 More studies supporting cardio-protective benefits from omega-3 fatty acids
  • References
  • Fifteen
  • Psychological disorders and omega-3s
  • 15.1 Introduction to the role of omega-3s in psychological disorders
  • 15.2 Depression
  • 15.2.1 Postpartum depression and pre-term birth
  • 15.2.1.1 Pre-term birth
  • 15.2.2 Manic depression ("bipolar disorder")
  • 15.2.3 Depression and alcoholism
  • 15.3 Schizophrenia
  • 15.4 Anxiety disorder
  • 15.5 Sleep disturbance
  • References
  • Sixteen
  • Age-related cognitive decline and omega-3
  • 16.1 Dementia
  • 16.2 Alzheimer disease
  • 16.2.1 Parkinson disease (PD)
  • References
  • Further reading
  • Seventeen
  • Vision and Omega-3
  • 17.1 Age-related macular degeneration (AMD)
  • 17.2 Dry eye syndrome (DES) or meibomian gland dysfunction (MGD)
  • References
  • Eighteen
  • Cancer and omega-3
  • 18.1 Seven ways of anti-cancer support provided by omega-3
  • 18.2 Breast cancer
  • 18.3 Intestinal- and colon cancer
  • 18.4 Prostate cancer
  • References
  • Nineteen
  • Insulin resistance, diabetes, metabolic syndrome, and omega-3
  • 19.1 Diabetes (Type-II) and obesity
  • 19.2 Adiponectin and its role for body-weight management
  • 19.3 Leptin and its role for body-weight management
  • 19.4 Obesity, metabolic syndrome, and insulin resistance (diabetes mellitus type II)
  • References
  • Twenty
  • Immune health and omega-3
  • 20.1 The inflammatory response (example: COVID-19 infection)
  • 20.2 Cytokines (TNF, IL-1, and IL-6) and the immune response
  • 20.3 Immune system efficacy depends on omega-3
  • 20.4 Autoimmune diseases and omega-3
  • 20.4.1 Rheumatoid arthritis
  • 20.4.2 Psoriasis and neurodermatitis.
  • 20.4.3 Inflammatory bowel disease (IBD), ulcerative colitis, Crohns disease, and omega-3
  • 20.4.4 Hair loss due to intense inflammatory conditions
  • References
  • Twenty-One
  • Bone/muscle health and omega-3
  • 21.1 Osteoporosis and omega-3
  • 21.2 Age-related sarcopenia (muscle loss) and omega-3
  • References
  • wenty-Two
  • Omega-3 supply, natural resources and our responsibility for future generations
  • Twenty-Three
  • Questions and answers
  • 23.1 Is vegetable/algae sourced EPA and DHA the same as marine/fish oil EPA and DHA?
  • 23.2 How much omega-3 do we need every day?
  • 23.3 What is the "omega-3 index"?-Test your patients need for omega-3 supplementation
  • 23.4 Are there different omega-3 requirements for men and women?
  • 23.5 Are there different omega-3 requirements with growing age?
  • 23.6 Are there different omega-3 requirements depending on digestion, metabolism, and medication?
  • 23.7 How does the daily diet impact my omega-3 requirement?
  • 23.8 What is the best time of the day to take omega-3 supplementation?
  • 23.9 Why should I take my omega-3 supplement, if possible, together with a meal containing phospholipids?
  • 23.10 How long do I have to take my omega-3 supplementation?
  • 23.11 Should I choose a highly concentrated omega-3 formulation, a natural fish oil, or simply eat more fish/seafood dishes per week?
  • 23.12 Salmon, tuna, sardine, or anchovy oil?
  • 23.13 Fish oil or algae oils?
  • 23.14 Ethyl ester (EE) or triglycerides (TGs)?
  • 23.15 Monoglycerides or phospholipids (krill oil)?
  • 23.16 EPA or DHA?
  • 23.17 Can plant omega-3 (ALA) convert to EPA or DHA?
  • 23.18 Can EPA convert in vivo to DHA and vice versa?
  • 23.19 Do omega-3 fatty acids, especially DHA, increase female and male fertility?
  • 23.20 Is DHA supplementation important for the fertility of healthy vegan men?.
  • 23.21 Does DHA supplementation reduce early preterm birth (EPTB)?
  • 23.22 Does DHA supplementation reduce heart frequency (pulse) and increase the heart rate variability (hrv)?
  • 23.23 Does only EPA reduce blood triglyceride levels? What about DHA?
  • 23.24 Do omega-3 fatty acids (EPA, DHA) reduce elevated blood cholesterol level?
  • 23.25 Can EPA and/or DHA supplementation lower elevated blood pressure?
  • 23.26 What are the two most important health benefits from Omega-3 (EPA+DHA) supplementation?
  • 23.27 Are omega-3 fatty acids (EPA+DHA) "silver bullets" that cure and prevent everything?
  • 23.28 "It's in my genes ... I can't do anything ..." is this correct?
  • 23.29 Can I replace DHA by any other similar molecule?
  • 23.30 If I take every day 1g of EPA and 1g of DHA, will that guarantee that I will never have a heart attack nor suffer from age- ...
  • 23.31 Is the daily intake of EPA and DHA the only thing I must care about when I age?
  • 23.32 Can I give omega-3 EPA and/or DHA to my dog or cat?
  • 23.33 Is there a difference between an omega-3 EPA/DHA concentrate obtained by distillation or supercritical fluid chromatography ...
  • References
  • Appendix A
  • Index
  • Back Cover.