http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
a scientific approach to healthy aging and optimized nutrition
Omega-3 Fatty Acids: A Scientific Approach to Healthy Ageing and Optimized Nutrition looks at the biochemistry of long chain fatty acids and their importance to health, well-being, and the reduction of inflammation in the body. Divided into two parts, the book first explains the history, chemical background, and physiological pathways of how EPA and DHA influence our inflammatory response and their importance as structural building blocks within our cell membranes. Readers will learn about increasing the anti-inflammatory effects from polyunsaturated-fatty-acid intake by combining Omega-3s and Omega-6s, as well as the differences, safety aspects, nutritional values of plant Omegas verse animal Omegas. In additions, sections will update on the benefits of different Omega fatty acids derived from various food sources such as seeds, fish, eggs, and nuts. Part Two is dedicated to healthy aging and discusses the results of numerous clinical trials and mechanisms of action that address heart, immune, bone, muscle, cognitive, and vision health. Readers will gain insight to methods of sustainable sourcing to ensure maximum benefits and optimized nutrition.
Front Cover -- Omega-3 Fatty Acids -- Omega-3 Fatty Acids: A Scientific Approach to Healthy Aging and Optimized Nutrition -- Copyright -- Contents -- Foreword -- List of abbreviations -- One -- Introduction-Why the inclusion of dietary omega-3 fatty acids allowed the development of Homo sapiens and sti ... -- References -- Two -- Lipids, fats, and oils -- 2.1 History -- 2.2 Fats and oils -- 2.3 Dietary lipids and their classification -- 2.3.1 Fatty acids -- 2.3.1.1 Saturated and unsaturated fatty acids -- 2.3.1.2 Monounsaturated fatty acids (with one double bond) -- 2.3.1.3 Polyunsaturated fatty acids (with more than one double bond) -- 2.3.2 Triglycerides -- 2.3.2.1 Triglycerides (TGs) versus ethyl esters (EEs)? -- 2.4 Sources of omega-3 EPA and DHA -- References -- Three -- Bioavailability -- 3.1 Lipid digestion and absorption -- 3.2 Relative Bioavailability Index for EEs, FFAs, TGs, and rTGs -- References -- Four -- Metabolic routes for fatty acids -- 4.1 Reaching the site of beta-oxidation -- 4.2 Inclusion into tissue cell membrane -- 4.3 Important derivates from EPA and DHA -- 4.3.1 Prostaglandins, resolvins, protectins, and maresins -- 4.3.1.1 Prostaglandin-E1 (PGE-1) -- 4.3.1.2 Prostaglandin-E2 (PGE-2) -- 4.3.1.3 Prostaglandin-E3 (PGE-3) -- 4.3.1.4 Resolvins, protectins, and maresins -- References -- Five -- Creating anti-inflammatory synergies with EPA/DHA -- 5.1 Simplified model of the inflammatory response process -- 5.2 Combination of EPA and DHA with omega-6 GLA -- 5.3 Combination of EPA and DHA with aspirin -- References -- Six -- Essential fatty acids and the importance of a balanced omega-6-to-omega-3 ratio in our diet -- References -- Seven -- Vegetable-versus animal omega-3 -- 7.1 Vegetable omega-3 -- 7.1.1 Alpha-linolenic acid (ALA) -- 7.1.2 Stearidonic acid (SDA) -- 7.2 Animal omega-3s.
7.2.1 Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) -- 7.2.1.1 EPA versus DHA -- 7.2.2 DPA-Greenland seal oil -- 7.2.3 Eicosatetraenoic acid (ETA) -- 7.2.4 Krill oil-EPA and DHA in phospholipid form -- References -- Eight -- Omega-3 dietary supplements versus omega-3 enriched food -- 8.1 Fish oil capsules versus omega-3 concentrates -- 8.2 Omega-3 enriched foods -- Reference -- Nine -- Approved health claims, recommended daily intakes, and safety -- 9.1 FDA-Food and drug administration (USA) -- 9.1.1 Safety -- 9.1.2 Qualified health claims -- 9.1.3 Nutrient content claims -- 9.2 EFSA-European Food Safety Authority (EU) -- 9.2.1 Safety -- 9.2.2 Qualified health claims -- 9.2.3 Nutrient content claims -- 9.3 Other authorities or associations -- 9.4 Safety of omega-3 -- References -- Ten -- Fish oil and omega-3 concentrate production and PUFA-oxidation control -- 10.1 Fish oil and omega-3 concentrate production -- 10.2 Oxidation of polyunsaturated fatty acids (PUFAs) -- References -- Eleven -- Reading and understanding the label -- 11.1 How long should you take omega-3s? -- 11.2 Do I need more EPA or more DHA? -- 11.3 Read and understand the label -- Twelve -- Healthy aging with omega-3's -- 12.1 What is aging? -- 12.2 The omega-6 to omega-3 ratio in our diet, senior health, and longevity -- References -- Thirteen -- How to determine your individual daily omega-3 dose and to distinguish between primary and secondary ris ... -- 13.1 The "omega-6 status" -- 13.2 The omega-3 index -- 13.3 Primary- and secondary health risk factors -- References -- Fourteen -- Cardiovascular health and Omega-3s -- 14.1 Sudden cardiac death -- 14.2 Stress and sudden cardiac death -- 14.3 Heart failure -- 14.4 Heart attack/heart infarct -- 14.4.1 Arteriosclerosis and the heart-attack-model -- 14.4.2 Cholesterol and hypercholesterolemia.
14.4.2.1 Is cholesterol a good cardiovascular risk factor? -- 14.4.2.2 Understanding blood cholesterol -- 14.4.2.3 Does DHA increase blood LDL-cholesterol? -- 14.5 Hypertriglyceridemia/dyslipidemia -- 14.6 More studies supporting cardio-protective benefits from omega-3 fatty acids -- References -- Fifteen -- Psychological disorders and omega-3s -- 15.1 Introduction to the role of omega-3s in psychological disorders -- 15.2 Depression -- 15.2.1 Postpartum depression and pre-term birth -- 15.2.1.1 Pre-term birth -- 15.2.2 Manic depression ("bipolar disorder") -- 15.2.3 Depression and alcoholism -- 15.3 Schizophrenia -- 15.4 Anxiety disorder -- 15.5 Sleep disturbance -- References -- Sixteen -- Age-related cognitive decline and omega-3 -- 16.1 Dementia -- 16.2 Alzheimer disease -- 16.2.1 Parkinson disease (PD) -- References -- Further reading -- Seventeen -- Vision and Omega-3 -- 17.1 Age-related macular degeneration (AMD) -- 17.2 Dry eye syndrome (DES) or meibomian gland dysfunction (MGD) -- References -- Eighteen -- Cancer and omega-3 -- 18.1 Seven ways of anti-cancer support provided by omega-3 -- 18.2 Breast cancer -- 18.3 Intestinal- and colon cancer -- 18.4 Prostate cancer -- References -- Nineteen -- Insulin resistance, diabetes, metabolic syndrome, and omega-3 -- 19.1 Diabetes (Type-II) and obesity -- 19.2 Adiponectin and its role for body-weight management -- 19.3 Leptin and its role for body-weight management -- 19.4 Obesity, metabolic syndrome, and insulin resistance (diabetes mellitus type II) -- References -- Twenty -- Immune health and omega-3 -- 20.1 The inflammatory response (example: COVID-19 infection) -- 20.2 Cytokines (TNF, IL-1, and IL-6) and the immune response -- 20.3 Immune system efficacy depends on omega-3 -- 20.4 Autoimmune diseases and omega-3 -- 20.4.1 Rheumatoid arthritis -- 20.4.2 Psoriasis and neurodermatitis.
20.4.3 Inflammatory bowel disease (IBD), ulcerative colitis, Crohns disease, and omega-3 -- 20.4.4 Hair loss due to intense inflammatory conditions -- References -- Twenty-One -- Bone/muscle health and omega-3 -- 21.1 Osteoporosis and omega-3 -- 21.2 Age-related sarcopenia (muscle loss) and omega-3 -- References -- wenty-Two -- Omega-3 supply, natural resources and our responsibility for future generations -- Twenty-Three -- Questions and answers -- 23.1 Is vegetable/algae sourced EPA and DHA the same as marine/fish oil EPA and DHA? -- 23.2 How much omega-3 do we need every day? -- 23.3 What is the "omega-3 index"?-Test your patients need for omega-3 supplementation -- 23.4 Are there different omega-3 requirements for men and women? -- 23.5 Are there different omega-3 requirements with growing age? -- 23.6 Are there different omega-3 requirements depending on digestion, metabolism, and medication? -- 23.7 How does the daily diet impact my omega-3 requirement? -- 23.8 What is the best time of the day to take omega-3 supplementation? -- 23.9 Why should I take my omega-3 supplement, if possible, together with a meal containing phospholipids? -- 23.10 How long do I have to take my omega-3 supplementation? -- 23.11 Should I choose a highly concentrated omega-3 formulation, a natural fish oil, or simply eat more fish/seafood dishes per week? -- 23.12 Salmon, tuna, sardine, or anchovy oil? -- 23.13 Fish oil or algae oils? -- 23.14 Ethyl ester (EE) or triglycerides (TGs)? -- 23.15 Monoglycerides or phospholipids (krill oil)? -- 23.16 EPA or DHA? -- 23.17 Can plant omega-3 (ALA) convert to EPA or DHA? -- 23.18 Can EPA convert in vivo to DHA and vice versa? -- 23.19 Do omega-3 fatty acids, especially DHA, increase female and male fertility? -- 23.20 Is DHA supplementation important for the fertility of healthy vegan men?.
23.21 Does DHA supplementation reduce early preterm birth (EPTB)? -- 23.22 Does DHA supplementation reduce heart frequency (pulse) and increase the heart rate variability (hrv)? -- 23.23 Does only EPA reduce blood triglyceride levels? What about DHA? -- 23.24 Do omega-3 fatty acids (EPA, DHA) reduce elevated blood cholesterol level? -- 23.25 Can EPA and/or DHA supplementation lower elevated blood pressure? -- 23.26 What are the two most important health benefits from Omega-3 (EPA+DHA) supplementation? -- 23.27 Are omega-3 fatty acids (EPA+DHA) "silver bullets" that cure and prevent everything? -- 23.28 "It's in my genes ... I can't do anything ..." is this correct? -- 23.29 Can I replace DHA by any other similar molecule? -- 23.30 If I take every day 1g of EPA and 1g of DHA, will that guarantee that I will never have a heart attack nor suffer from age- ... -- 23.31 Is the daily intake of EPA and DHA the only thing I must care about when I age? -- 23.32 Can I give omega-3 EPA and/or DHA to my dog or cat? -- 23.33 Is there a difference between an omega-3 EPA/DHA concentrate obtained by distillation or supercritical fluid chromatography ... -- References -- Appendix A -- Index -- Back Cover.
Includes bibliographical references and index.