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Nanozymes : approachable bio-applications /

The book 'Nanozymes' provides an extensive examination of nanozymes, a class of nanomaterials with enzyme-like properties. It covers a broad spectrum of topics, including the history, types, synthesis methods, catalytic activities, and applications of nanozymes in various fields such as ca...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Tripathi, Ravi Mani (Editor)
Format: eBook
Language:English
Published: Amsterdam, Netherlands ; Cambridge, MA. United States : Elsevier, [2024]
Series:Micro & nano technologies.
Subjects:
Enzymes.
Nanotechnology.
Nanotechnologie.
enzyme.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Intro
  • Nanozymes: Approachable Bio-applications
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter 1: An overview of nanozymes
  • 1.1. Introduction
  • 1.2. A brief history of nanozyme research and development
  • 1.3. Definition of nanozymes
  • 1.4. Types of nanozymes
  • 1.4.1. Metal-based nanozymes
  • 1.4.2. Metal oxide-based nanozymes
  • 1.4.3. Carbon-based nanozymes
  • 1.4.4. Hybrid nanozymes
  • 1.5. Catalytic activities of nanozymes
  • 1.6. Synthesis methods
  • 1.7. Advantages of using nanozymes over traditional enzymes
  • 1.7.1. Enhanced stability
  • 1.7.2. Ease of synthesis
  • 1.7.3. Large-scale production
  • 1.7.4. Tunable properties
  • 1.7.5. Versatility
  • 1.8. Factors influencing the performance of nanozymes
  • 1.8.1. Aggregation
  • 1.8.2. Surface modification
  • 1.8.3. Size and configuration
  • 1.8.4. Environment
  • 1.8.5. Chemical stability
  • 1.8.6. Storage
  • 1.9. Applications of nanozymes in bioapplications
  • 1.9.1. Biomedical imaging
  • 1.9.2. Biosensing
  • 1.9.3. Immunoassays
  • 1.9.4. Theragnostic
  • 1.9.5. Drug delivery
  • 1.9.6. Antibacterial therapy
  • 1.9.7. Environmental applications of nanozymes
  • 1.9.8. Industrial applications of nanozymes
  • 1.9.8.1. Catalysis
  • 1.9.8.2. Manufacturing processes
  • 1.10. Limitations of nanozymes
  • 1.10.1. Limited substrate specificity
  • 1.10.2. Reproducibility challenges
  • 1.10.3. Limited understanding
  • 1.10.4. Regulatory hurdles
  • 1.11. Future directions for nanozyme research and development
  • 1.11.1. Smart nanozymes
  • 1.11.2. Integration with other nanomaterials
  • 1.11.3. In vivo applications
  • 1.11.4. Environmental applications
  • 1.12. Conclusion
  • References
  • Chapter 2: Classification of nanozymes
  • 2.1. Introduction
  • 2.2. Oxidoreductase-mimetic nanozymes
  • 2.2.1. Oxidase-mimetic nanozymes
  • 2.2.1.1. Laccase-mimetic nanozymes.
  • 2.2.1.2. Sulfite oxidase-mimetc nanozymes
  • 2.2.1.3. Glucose oxidase-mimetic nanozymes
  • 2.2.2. Catalase nanozymes
  • 2.2.3. Peroxidase-mimetic nanozymes
  • 2.2.3.1. Glutathione peroxidase-mimetic nanozymes
  • 2.2.3.2. Haloperoxidase-mimetic nanozymes
  • 2.2.4. Special oxidoreductase-mimetic nanozymes
  • 2.2.5. Superoxide dismutase nanozymes
  • 2.2.5.1. Cerium-based SOD-mimetic nanozymes
  • 2.2.5.2. Carbon-based SOD nanozymes
  • 2.2.5.3. Other metals
  • 2.3. Hydrolase family
  • 2.4. Conclusion
  • References
  • Chapter 3: A review on nanozymes mechanisms and kinetics
  • 3.1. Introduction
  • 3.2. Peroxidase-like activity
  • 3.2.1. Free radical (Fenton) mechanism
  • 3.2.2. Electron-transfer mechanism
  • 3.2.3. Mechanisms of carbon systems
  • 3.2.4. Mechanism of nanoceria
  • 3.3. Superoxide dismutase-like activity
  • 3.3.1. Mechanism of metal and metal oxides
  • 3.3.2. Mechanism of nanoceria
  • 3.3.3. Mechanism of carbon systems
  • 3.4. Oxidase-like activity
  • 3.4.1. Mechanism of metals
  • 3.4.2. Mechanism of nanoceria
  • 3.4.3. Mechanism of carbon systems
  • 3.5. Catalase-like activity
  • 3.5.1. Homolytic mechanism
  • 3.5.2. Heterolytic mechanism
  • 3.6. Hydrolase-like activity
  • 3.7. Dehydrogenase-like activity
  • 3.8. Kinetic modeling of nanozyme activity
  • 3.9. Conclusions
  • References
  • Chapter 4: Recent progress in the synthesis of nanozymes and their functionalization
  • 4.1. Introduction
  • 4.2. Classification of nanozymes
  • 4.2.1. Peroxidase mimics
  • 4.2.1.1. Iron-based
  • 4.2.1.2. Vanadium-based nanozymes
  • 4.2.1.3. Manganese-based nanozymes
  • 4.2.1.4. Other peroxidase-mimicking enzyme
  • 4.2.2. Oxidase-mimic nanozymes
  • 4.2.2.1. Gold-based nanozymes
  • 4.2.2.2. Platinum-based nanozymes
  • 4.2.2.3. Molybdenum-based nanozymes
  • 4.2.2.4. Copper-based nanozymes
  • 4.2.3. SOD mimics
  • 4.2.3.1. Cerium-based nanozymes.
  • 4.2.3.2. Carbon-based nanozymes
  • 4.2.4. Catalase mimics
  • 4.2.5. Multifunctional nanozymes
  • 4.3. Synthesis of nanozymes
  • 4.3.1. Top-down synthesis
  • 4.3.2. Bottom-up synthesis
  • 4.4. The impact of surface modification on the activity of nanozymes
  • 4.4.1. Functionalization gives rise to different nanozyme activity for a single nanoparticle: Case studies of Mn, Fe, and ...
  • 4.5. Conclusion and future perspective
  • Acknowledgment
  • References
  • Chapter 5: Construction of functionally specific nanozymes for cancer theragnostic
  • 5.1. Introduction
  • 5.2. Implementation of nanozymes for the preparation of theragnostics in cancer
  • 5.3. Nanozymes in cancer bioimaging
  • 5.4. Nanozymes in cancer diagnosis
  • 5.5. Conclusion
  • Acknowledgment
  • References
  • Chapter 6: Opportunities and trends in therapeutics application of nanozymes
  • 6.1. Introduction
  • 6.2. Classification of nanozymes
  • 6.2.1. Oxidase-mimic nanozymes
  • 6.2.2. Peroxidase-mimic nanozymes
  • 6.2.3. Catalase-mimic nanozymes
  • 6.2.4. Superoxidase-mimic nanozymes
  • 6.3. Therapeutic applications of nanozymes
  • 6.3.1. Nanozyme-based cancer therapy
  • 6.3.2. Nanozyme-based infectious disease therapy
  • 6.3.3. Nanozyme-based cardiovascular disease therapy
  • 6.3.4. Nanozyme-based neurodegenerative disorders therapy
  • 6.3.5. Nanozyme-based drug delivery
  • 6.4. Future prospectives and challenges
  • 6.4.1. Conclusion
  • Acknowledgments
  • References
  • Chapter 7: Nanozyme-based antibacterials against bacterial infections
  • 7.1. Introduction
  • 7.2. Mechanism of antibacterial nanozymes
  • 7.2.1. ROS regulation
  • 7.2.2. HOBr/Cl generation
  • 7.2.3. Extracellular DNA clearance
  • 7.3. Design consideration in antibacterial nanozymes
  • 7.3.1. Metal-based nanozymes
  • 7.3.2. Carbon-based nanozymes
  • 7.3.3. Single-atom nanozymes
  • 7.3.4. MOFs-based nanozymes.
  • 7.3.5. Other classes of nanozymes
  • 7.4. Biocompatibility of antibacterial nanozymes
  • 7.5. Combinatorial applications of antibacterial nanozymes
  • 7.5.1. Integration of nanozymes in multifunctional antibacterial biomaterial designs
  • 7.5.2. Photodynamic and photothermal inactivation with nanozymes
  • 7.6. Conclusion and future directions
  • Acknowledgments
  • References
  • Chapter 8: Nanozymes-based detection of clinically important pathogens
  • 8.1. Introduction
  • 8.2. Types of nanozymes and the mechanisms of nanozyme catalysis
  • 8.3. Nanozyme applications in pathogen detection
  • 8.3.1. Detection of bacterial pathogens
  • 8.3.2. Viral detection via nanozymes
  • 8.3.3. Detection of fungi and parasites
  • 8.4. Conclusion
  • 8.5. Challenges and future perspectives
  • References
  • Chapter 9: Nanozyme for diabetes care
  • 9.1. Introduction
  • 9.1.1. Types of DM
  • 9.2. Methods
  • 9.2.1. Glucose detection technologies: From traditional to innovative methods
  • 9.2.2. The development of biosensors and point-of-care devices for DM with nanoenzymes
  • 9.2.3. Alternative diabetes care methods: Insulin delivery using nanozymes
  • 9.2.4. Challenging diabetic wounds with nanozymes
  • 9.2.4.1. Causes of diabetic wounds
  • 9.2.5. Therapeutic approaches with nanozymes
  • 9.3. Conclusion
  • Acknowledgments
  • References
  • Chapter 10: Nanozymes-based multifunctional platforms for uric acid detection in patients
  • 10.1. Introduction
  • 10.2. Nanozymes: Concepts and properties
  • 10.3. Uric acid detection using nanozymes
  • 10.3.1. Colorimetric sensor
  • 10.3.2. Electrochemical sensor
  • 10.3.3. Fluorescence sensor
  • 10.3.4. Surface-enhanced Raman scattering (SERS) sensors
  • 10.4. Challenges and future directions
  • 10.5. Conclusion
  • Acknowledgments
  • References.