Nanozymes : approachable bio-applications /

The book 'Nanozymes' provides an extensive examination of nanozymes, a class of nanomaterials with enzyme-like properties. It covers a broad spectrum of topics, including the history, types, synthesis methods, catalytic activities, and applications of nanozymes in various fields such as ca...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Tripathi, Ravi Mani (Editor)
Format: eBook
Language:English
Published: Amsterdam, Netherlands ; Cambridge, MA. United States : Elsevier, [2024]
Series:Micro & nano technologies.
Subjects:
Online Access:Connect to the full text of this electronic book

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588 |a Description based on online resource; title from digital title page (viewed on September 11, 2024). 
505 0 |a Intro -- Nanozymes: Approachable Bio-applications -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1: An overview of nanozymes -- 1.1. Introduction -- 1.2. A brief history of nanozyme research and development -- 1.3. Definition of nanozymes -- 1.4. Types of nanozymes -- 1.4.1. Metal-based nanozymes -- 1.4.2. Metal oxide-based nanozymes -- 1.4.3. Carbon-based nanozymes -- 1.4.4. Hybrid nanozymes -- 1.5. Catalytic activities of nanozymes -- 1.6. Synthesis methods -- 1.7. Advantages of using nanozymes over traditional enzymes -- 1.7.1. Enhanced stability -- 1.7.2. Ease of synthesis -- 1.7.3. Large-scale production -- 1.7.4. Tunable properties -- 1.7.5. Versatility -- 1.8. Factors influencing the performance of nanozymes -- 1.8.1. Aggregation -- 1.8.2. Surface modification -- 1.8.3. Size and configuration -- 1.8.4. Environment -- 1.8.5. Chemical stability -- 1.8.6. Storage -- 1.9. Applications of nanozymes in bioapplications -- 1.9.1. Biomedical imaging -- 1.9.2. Biosensing -- 1.9.3. Immunoassays -- 1.9.4. Theragnostic -- 1.9.5. Drug delivery -- 1.9.6. Antibacterial therapy -- 1.9.7. Environmental applications of nanozymes -- 1.9.8. Industrial applications of nanozymes -- 1.9.8.1. Catalysis -- 1.9.8.2. Manufacturing processes -- 1.10. Limitations of nanozymes -- 1.10.1. Limited substrate specificity -- 1.10.2. Reproducibility challenges -- 1.10.3. Limited understanding -- 1.10.4. Regulatory hurdles -- 1.11. Future directions for nanozyme research and development -- 1.11.1. Smart nanozymes -- 1.11.2. Integration with other nanomaterials -- 1.11.3. In vivo applications -- 1.11.4. Environmental applications -- 1.12. Conclusion -- References -- Chapter 2: Classification of nanozymes -- 2.1. Introduction -- 2.2. Oxidoreductase-mimetic nanozymes -- 2.2.1. Oxidase-mimetic nanozymes -- 2.2.1.1. Laccase-mimetic nanozymes. 
505 8 |a 2.2.1.2. Sulfite oxidase-mimetc nanozymes -- 2.2.1.3. Glucose oxidase-mimetic nanozymes -- 2.2.2. Catalase nanozymes -- 2.2.3. Peroxidase-mimetic nanozymes -- 2.2.3.1. Glutathione peroxidase-mimetic nanozymes -- 2.2.3.2. Haloperoxidase-mimetic nanozymes -- 2.2.4. Special oxidoreductase-mimetic nanozymes -- 2.2.5. Superoxide dismutase nanozymes -- 2.2.5.1. Cerium-based SOD-mimetic nanozymes -- 2.2.5.2. Carbon-based SOD nanozymes -- 2.2.5.3. Other metals -- 2.3. Hydrolase family -- 2.4. Conclusion -- References -- Chapter 3: A review on nanozymes mechanisms and kinetics -- 3.1. Introduction -- 3.2. Peroxidase-like activity -- 3.2.1. Free radical (Fenton) mechanism -- 3.2.2. Electron-transfer mechanism -- 3.2.3. Mechanisms of carbon systems -- 3.2.4. Mechanism of nanoceria -- 3.3. Superoxide dismutase-like activity -- 3.3.1. Mechanism of metal and metal oxides -- 3.3.2. Mechanism of nanoceria -- 3.3.3. Mechanism of carbon systems -- 3.4. Oxidase-like activity -- 3.4.1. Mechanism of metals -- 3.4.2. Mechanism of nanoceria -- 3.4.3. Mechanism of carbon systems -- 3.5. Catalase-like activity -- 3.5.1. Homolytic mechanism -- 3.5.2. Heterolytic mechanism -- 3.6. Hydrolase-like activity -- 3.7. Dehydrogenase-like activity -- 3.8. Kinetic modeling of nanozyme activity -- 3.9. Conclusions -- References -- Chapter 4: Recent progress in the synthesis of nanozymes and their functionalization -- 4.1. Introduction -- 4.2. Classification of nanozymes -- 4.2.1. Peroxidase mimics -- 4.2.1.1. Iron-based -- 4.2.1.2. Vanadium-based nanozymes -- 4.2.1.3. Manganese-based nanozymes -- 4.2.1.4. Other peroxidase-mimicking enzyme -- 4.2.2. Oxidase-mimic nanozymes -- 4.2.2.1. Gold-based nanozymes -- 4.2.2.2. Platinum-based nanozymes -- 4.2.2.3. Molybdenum-based nanozymes -- 4.2.2.4. Copper-based nanozymes -- 4.2.3. SOD mimics -- 4.2.3.1. Cerium-based nanozymes. 
505 8 |a 4.2.3.2. Carbon-based nanozymes -- 4.2.4. Catalase mimics -- 4.2.5. Multifunctional nanozymes -- 4.3. Synthesis of nanozymes -- 4.3.1. Top-down synthesis -- 4.3.2. Bottom-up synthesis -- 4.4. The impact of surface modification on the activity of nanozymes -- 4.4.1. Functionalization gives rise to different nanozyme activity for a single nanoparticle: Case studies of Mn, Fe, and ... -- 4.5. Conclusion and future perspective -- Acknowledgment -- References -- Chapter 5: Construction of functionally specific nanozymes for cancer theragnostic -- 5.1. Introduction -- 5.2. Implementation of nanozymes for the preparation of theragnostics in cancer -- 5.3. Nanozymes in cancer bioimaging -- 5.4. Nanozymes in cancer diagnosis -- 5.5. Conclusion -- Acknowledgment -- References -- Chapter 6: Opportunities and trends in therapeutics application of nanozymes -- 6.1. Introduction -- 6.2. Classification of nanozymes -- 6.2.1. Oxidase-mimic nanozymes -- 6.2.2. Peroxidase-mimic nanozymes -- 6.2.3. Catalase-mimic nanozymes -- 6.2.4. Superoxidase-mimic nanozymes -- 6.3. Therapeutic applications of nanozymes -- 6.3.1. Nanozyme-based cancer therapy -- 6.3.2. Nanozyme-based infectious disease therapy -- 6.3.3. Nanozyme-based cardiovascular disease therapy -- 6.3.4. Nanozyme-based neurodegenerative disorders therapy -- 6.3.5. Nanozyme-based drug delivery -- 6.4. Future prospectives and challenges -- 6.4.1. Conclusion -- Acknowledgments -- References -- Chapter 7: Nanozyme-based antibacterials against bacterial infections -- 7.1. Introduction -- 7.2. Mechanism of antibacterial nanozymes -- 7.2.1. ROS regulation -- 7.2.2. HOBr/Cl generation -- 7.2.3. Extracellular DNA clearance -- 7.3. Design consideration in antibacterial nanozymes -- 7.3.1. Metal-based nanozymes -- 7.3.2. Carbon-based nanozymes -- 7.3.3. Single-atom nanozymes -- 7.3.4. MOFs-based nanozymes. 
505 8 |a 7.3.5. Other classes of nanozymes -- 7.4. Biocompatibility of antibacterial nanozymes -- 7.5. Combinatorial applications of antibacterial nanozymes -- 7.5.1. Integration of nanozymes in multifunctional antibacterial biomaterial designs -- 7.5.2. Photodynamic and photothermal inactivation with nanozymes -- 7.6. Conclusion and future directions -- Acknowledgments -- References -- Chapter 8: Nanozymes-based detection of clinically important pathogens -- 8.1. Introduction -- 8.2. Types of nanozymes and the mechanisms of nanozyme catalysis -- 8.3. Nanozyme applications in pathogen detection -- 8.3.1. Detection of bacterial pathogens -- 8.3.2. Viral detection via nanozymes -- 8.3.3. Detection of fungi and parasites -- 8.4. Conclusion -- 8.5. Challenges and future perspectives -- References -- Chapter 9: Nanozyme for diabetes care -- 9.1. Introduction -- 9.1.1. Types of DM -- 9.2. Methods -- 9.2.1. Glucose detection technologies: From traditional to innovative methods -- 9.2.2. The development of biosensors and point-of-care devices for DM with nanoenzymes -- 9.2.3. Alternative diabetes care methods: Insulin delivery using nanozymes -- 9.2.4. Challenging diabetic wounds with nanozymes -- 9.2.4.1. Causes of diabetic wounds -- 9.2.5. Therapeutic approaches with nanozymes -- 9.3. Conclusion -- Acknowledgments -- References -- Chapter 10: Nanozymes-based multifunctional platforms for uric acid detection in patients -- 10.1. Introduction -- 10.2. Nanozymes: Concepts and properties -- 10.3. Uric acid detection using nanozymes -- 10.3.1. Colorimetric sensor -- 10.3.2. Electrochemical sensor -- 10.3.3. Fluorescence sensor -- 10.3.4. Surface-enhanced Raman scattering (SERS) sensors -- 10.4. Challenges and future directions -- 10.5. Conclusion -- Acknowledgments -- References. 
520 |a The book 'Nanozymes' provides an extensive examination of nanozymes, a class of nanomaterials with enzyme-like properties. It covers a broad spectrum of topics, including the history, types, synthesis methods, catalytic activities, and applications of nanozymes in various fields such as cancer theragnostics, pathogen detection, diabetes care, environmental remediation, and food safety. The book discusses the advantages of nanozymes over traditional enzymes and explores their potential in therapeutic applications and diagnostics. It also addresses challenges, limitations, and future directions for research and development in nanozyme technology. The book is intended for researchers, practitioners, and professionals in fields related to nanotechnology, biomedicine, environmental science, and food safety. 
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