Transpathology : molecular imaging-based pathology /

Transpathology: Molecular Imaging-Based Pathology is a multidisciplinary reference on molecular imaging and pathology. The book is intended for professionals in the fields of molecular imaging, nuclear medicine, radiology, and pathology as well as students and clinical residents. The book describes...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Tian, Mei
Format:	eBook
Language:	English
Published:	[S.l.] : ELSEVIER, 2024.
Subjects:	Pathology, Molecular. Pathology, Molecular Pathologie moléculaire. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Front Cover
Transpathology
Copyright Page
Dedication
Contents
List of contributors
Preface
Acknowledgment
1 From molecular imaging to transpathology: general principles
1.1 Introduction
1.2 Recent advances in molecular imaging (instruments and probes)
1.3 Progress in pathology
1.4 Definition of "transpathology"
References
2 Positron emission tomography instrumentation and image reconstruction
2.1 Introduction
2.2 Physics of positron emission tomography imaging
2.2.1 Positron emission tomography scan procedure
2.2.2 Positron emission tomography detector
2.2.3 Positron emission tomography scanner sensitivity
2.2.4 Positron emission tomography scanner spatial resolution
2.2.5 Positron emission tomography scanner timing resolution
2.3 Positron emission tomography scanner
2.3.1 Whole-body positron emission tomography
2.3.2 Total-body positron emission tomography
2.3.3 Dedicated brain positron emission tomography
2.3.4 Positron emission tomography/Magnetic resonance imaging
2.3.5 Small animal positron emission tomography
2.4 Image reconstruction
2.4.1 Sinogram
2.4.2 Filtered back projection reconstruction
2.4.3 Iterative reconstruction
2.4.4 Deep learning-based reconstruction
2.5 Data correction
2.5.1 Random correction
2.5.2 Normalization
2.5.3 Attenuation correction
2.5.4 Scatter correction
2.5.5 Other corrections
2.6 Future direction
References
3 PET/SPECT: quantitative imaging and data analysis
3.1 Introduction
3.2 Compartmental model with plasma input
3.2.1 One-tissue compartment model
3.2.2 Two-tissue compartment model
3.2.3 Three-tissue compartment model
3.2.4 General compartmental modeling
3.3 Compartmental model with reference tissue input.
3.3.1 Theory of reference tissue model with parameter coupling
3.3.2 Full reference tissue with parameter coupling-RTM4P
3.3.3 "Watabe" reference tissue model with parameter coupling-RTM5P
3.3.4 Simplified reference tissue model with parameter coupling-RTM3P
3.3.5 Application
3.4 Graphical analysis
3.4.1 Graphical analysis with plasma input
3.4.1.1 Patlak plot
3.4.1.2 Logan plot
3.4.1.3 Relative-equilibrium-based graphical plot
3.4.1.4 Occupancy (Lassen) plot
3.4.2 Graphical analysis with reference input
3.4.2.1 Logan plot with reference tissue input
3.4.2.2 RE-GP plot with reference tissue input
3.5 Parameter estimation and model fitting
3.5.1 Linearization for model fitting
3.5.1.1 One-tissue compartmental model
3.5.1.2 Two-tissue compartmental model
3.5.1.3 Simplified reference tissue model
3.5.2 Model fitting with constraint
3.5.2.1 Kinetic modeling with physiology constraint
3.5.2.2 Parametric imaging with spatial constraint
3.5.2.2.1 Clustering-based linear least square fitting method
3.5.2.2.2 Linear regression with spatial constraint for generation of parametric images
3.6 Total-body kinetic modeling
3.6.1 Total-body input function
3.6.2 Multiple compartmental modeling
3.6.3 Multiple graphical analysis
3.7 Conclusion
References
4 Magnetic resonance histology
4.1 Introduction
4.2 Histology and high-field magnetic resonance imaging
4.3 Protocols for magnetic resonance imaging histology preparation
4.4 Coregistration of magnetic resonance imaging and histological datasets
4.5 The advantage of high-field magnetic resonance
References
5 Novel biomedical imaging technology for high-resolution histological analysis
5.1 Introduction.
5.2 Dark-field reflectance ultraviolet microscopy for rapid and label-free histological imaging of unprocessed surgical tissues
5.3 High-resolution three-dimensional slide-free histopathology with light sheet fluorescence microscopy and tissue clearing
5.4 High-frequency ultrasound for vessel structural imaging
5.5 High-resolution imaging in magnetic resonance imaging: relating with histology and pathology
5.5.1 Structural imaging
5.5.2 Diffusion imaging
5.5.3 Susceptibility-weighted imaging
5.6 High spatial resolution positron emission tomography imaging
References
6 Photoacoustic imaging
6.1 Introduction
6.2 Multicontrast and multiscale photoacoustic imaging
6.2.1 Contrast mechanisms of photoacoustic imaging
6.2.1.1 Endogenous contrasts
6.2.1.2 Exogenous contrasts
6.2.1.3 Combinations with other imaging modalities
6.2.2 Major configurations of photoacoustic imaging
6.2.2.1 Photoacoustic microscopy
6.2.2.2 Photoacoustic computed tomography
6.2.2.3 Photoacoustic endoscopy
6.2.2.4 Microwave-induced thermoacoustic tomography
6.2.3 Principles of photoacoustic image formation
6.3 Photoacoustic imaging in preclinical research
6.3.1 High speed photoacoustic imaging of small animal brain functions
6.3.2 Photoacoustic computed tomography of small animal whole-body dynamics
6.3.3 Molecular photoacoustic imaging for cancer diagnosis and drug delivery
6.4 Photoacoustic imaging in clinical oncology
6.4.1 Cancer detection
6.4.1.1 Breast cancer screening
6.4.1.2 Skin cancer measurement
6.4.1.3 Prostate cancer imaging
6.4.2 Cancer diagnosis
6.4.2.1 Breast cancer diagnosis
6.4.2.2 Metastases detection
6.4.3 Cancer treatment
6.4.3.1 Treatment assessment
6.4.3.2 Guidance for surgical resection
6.5 Summary and outlook
References.
7 Optical imaging technologies and applications
7.1 Introduction
7.2 Photoacoustic microscopy
7.2.1 Instrumentation
7.2.2 Applications
7.3 Laser scanning fluorescence microscopy
7.3.1 Instrumentation
7.3.2 Applications
7.4 Coherent Raman scattering microscopy
7.5 Lens-free computational microscopy
7.6 Polarization microscopy
7.7 Light sheet fluorescence microscopy
7.7.1 Instrumentation
7.7.2 Applications
7.8 Optical projection tomography
7.8.1 Basic principles of optical projection tomography
7.8.2 Optical projection tomography imaging system
7.8.3 Optical projection tomography imaging methods
7.8.4 Biomedical application of optical projection tomography
References
8 Stimulated Raman histology
8.1 Introduction
8.2 Coherent Raman scattering microscopy
8.2.1 Coherent anti-Stokes scattering
8.2.2 Stimulated Raman scattering
8.3 Stimulated Raman histology
8.3.1 Label-free histopathology
8.3.2 Machine learning assisted imaging and diagnosis
8.4 Future perspective
References
9 Imaging of biological processes using positron emission tomography and single-photon emission computed tomography
9.1 Introduction
9.2 Radioactive probes
9.3 Nuclear imaging and biological processes
9.3.1 Cancer
9.3.1.1 Cell metabolism
9.3.1.2 Receptors and protein kinases
9.3.1.2.1 Fibroblast activation protein
9.3.1.2.2 Prostate specific membrane antigen
9.3.1.2.3 Somatostatin receptors
9.3.1.2.4 Epidermal growth factor receptor
9.3.1.2.5 Human epidermal growth factor receptor 2
9.3.1.2.6 Estrogen receptor
9.3.1.2.7 Poly (adenosine diphosphate ribose) polymerase
9.3.1.3 Cell proliferation
9.3.1.4 Angiogenesis
9.3.1.5 Hypoxia
9.3.1.6 Apoptosis
9.3.1.7 Tumor immune evasion
9.3.2 Cardiology
9.3.2.1 Myocardial perfusion imaging.