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Pili in mycobacterium tuberculosis : structure, function, and therapeutic advances /

Pili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTBC.

Bibliographic Details
Main Authors: Velayati, Ali Akbar (Author), Farnia, Parissa (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: London, United Kingdom : Academic Press, 2024.
Subjects:
Pili (Microbiology)
Mycobacterium tuberculosis.
Fimbriae.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Pili in Mycobacterium Tuberculosis
  • Copyright Page
  • Dedication
  • Contents
  • About the authors
  • 1 The structure and function of pili in bacteria
  • 1.1 The taxonomy of the genus Mycobacterium
  • 1.2 Different pili in bacteria genies
  • 1.2.1 Pili in Gram-negative bacteria
  • 1.2.1.1 Type I pili
  • 1.2.1.2 P pili
  • 1.2.1.3 Curli type
  • 1.2.1.4 Type III secretion
  • 1.2.1.5 Type IV pili
  • 1.2.1.6 Type IV secretion pili
  • 1.2.1.7 Chaperone/usher pili
  • 1.2.2 Pili in Gram-positive bacteria
  • 1.2.2.1 Sortase-assembled pili
  • 1.2.2.2 Type IV pili in Gram-positive bacteria
  • 1.2.2.3 Other pili
  • 1.3 The pili at genomic level
  • 1.4 The role and function of pili in diseases
  • References
  • Further reading
  • 2 The structure of pili under electron and atomic force microscopy
  • 2.1 Preparation of Mycobacterium tuberculosis for electron microscopy
  • 2.1.1 Transmission electron microscopy
  • 2.1.1.1 Support films on specimen grids
  • 2.1.1.2 Metal shadowing
  • 2.1.1.3 Negative staining
  • 2.1.1.4 Immuno-gold labeling
  • 2.1.2 Scanning electron microscopy
  • 2.2 Preparation of Mycobacterium tuberculosis for atomic force microscopy
  • 2.3 Preparation of different life cycle and susceptibility pattern of Mycobacterium tuberculosis
  • 2.3.1 Cell division in Mycobacterium tuberculosis
  • 2.3.1.1 FtsZ-ring assembly
  • 2.3.1.2 Place of septum formation
  • 2.3.1.3 Final stage of separation
  • 2.3.2 Sample preparation from clinical isolates of Mycobacterium tuberculosis with different susceptibility pattern
  • 2.3.3 Sample preparation for transmission electron microscopy
  • 2.3.4 Sample preparation for atomic force microscopy
  • 2.4 Differences of pili formation in Mycobacterium tuberculosis and their role in increase surveillance
  • References
  • Further reading
  • 3 The pili at genomic level.
  • 3.1 Whole genome of Mycobacterium tuberculosis
  • 3.1.1 Genome sequencing of Mycobacterium tuberculosis
  • 3.1.2 Genomic sequencing methods
  • 3.1.3 Application of whole-genome sequencing in tuberculosis infection
  • 3.1.4 Challenges with whole-genome sequencing
  • 3.2 Genes related to pili expression and function in tuberculosis and other Mycobacterium species
  • References
  • Further reading
  • 4 The design for drug delivery using pili in Mycobacterium tuberculosis
  • 4.1 Pili application in drug delivery in different bacteria
  • 4.2 Pili application in drug delivery in mycobacteria
  • References
  • Further reading
  • 5 Role of Mycobacterium tuberculosis pili in host
  • 5.1 The role of bacteria pili in host
  • 5.2 Role of Mycobacterium tuberculosis pili in host
  • References
  • Further reading
  • Index
  • Back Cover.