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Pharmacology in drug discovery and development : understanding drug response /

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"Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanis...

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Bibliographic Details
Main Author: Kenakin, Terrence P. (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: London, United Kingdom : Academic Press, [2024]
Edition:Third edition.
Subjects:
Developmental pharmacology.
Pharmacology.
Drug development.
Pharmacology
Pharmacologie du développement.
Pharmacologie.
Médicaments > Développement.
pharmacology.
Electronic books.
Livres numériques.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Pharmacology : the chemical control of physiology
  • Drug affinity and efficacy
  • Predicting agonist effect
  • Drug antagonism : orthosteric drug effects
  • Allosteric drug effects
  • Enzymes as drug targets
  • Pharmacokinetics I : permeation and metabolism
  • Pharmacokinetics II : distribution and multiple dosing
  • In vivo pharmacology
  • Safety pharmacology
  • The science of finding drug molecules I : applying pharmacology to discovery/target identification and validation
  • The science of finding drug molecules II : demonstrating target engagement and therapeutic value.