FUSED PYRANONES : multifaceted building blocks for molecular diversity /

The book 'Fused Pyranones: Multifaceted Building Blocks' delves into the chemistry of fused pyranones, particularly focusing on coumarins, chromones, and their derivatives. It serves as a comprehensive guide on the synthesis, chemical properties, and applications of these compounds in medi...

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Bibliographic Details
Main Author: Ram, Vishnu Ji
Corporate Author: ScienceDirect (Online service)
Other Authors: Pratap, Ramendra, Yadav, Pratik
Format: eBook
Language:English
Published: Amsterdam : Elsevier, 2024.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Intro
  • Fused Pyranones: Multifaceted Building Blocks for Molecular Diversity
  • Copyright
  • Contents
  • Preface
  • Author biographies
  • Chapter 1: Fused pyrones: Multifaceted building blocks for molecular diversity
  • 1.1. Introduction
  • References
  • Chapter 2: Characteristics of coumarins and fused coumarins
  • References
  • Chapter 3: Chemistry of natural and synthetic 2H-1-benzopyran-2-ones (coumarins)
  • 3.1. Introduction
  • 3.2. Chemistry of natural and synthetic coumarins
  • 3.2.1. Simple coumarins
  • 3.2.1.1. Simple prenylated coumarins
  • 3.2.1.2. Simple geranylated coumarins
  • 3.2.2. Furocoumarins (furanocoumarins)
  • 3.2.2.1. Linear furocoumarins
  • 3.2.2.2. Angular furocoumarins
  • 3.2.2.3. Natural furo[2,3-f]coumarins
  • 3.2.2.4. Natural furo[2,3-h]coumarins
  • 3.2.2.5. Biosynthesis of angular and linear furocoumarins
  • 3.2.3. Pyranocoumarins
  • 3.2.3.1. Natural linear pyrano[3,2-g]coumarins
  • 3.2.4. Dipyrano[2,3-f: 2,3-h]coumarines
  • 3.2.4.1. General synthesis of coumarins
  • 3.2.4.2. Chromen fused coumarin
  • References
  • Chapter 4: Chemistry of 1H-2-benzopyran-1-one (isocoumarin)
  • 4.1. Natural benzo[g]isocoumarins
  • 4.2. Dimeric benzo[g]isocoumarins
  • 4.3. Synthesis of isocoumarins
  • 4.4. Chemical reactivity
  • 4.4.1. Reaction with ammonia and amines
  • 4.4.2. Substitution reactions
  • References
  • Chapter 5: Chemistry of 4H-1-benzopyran-4-ones (chromones, or 4H-chromene-4-ones)
  • 5.1. Natural chromone alkaloids
  • 5.2. Natural fused chromones
  • 5.3. Synthetic furano[3,2-g]chromones
  • 5.3.1. Ethyl 5-methoxy-2-methylfuro[2,3-g]chromen-4-one-7-carboxyate
  • 5.4. Synthesis of 3-(4-methoxyphenyl)-8-(4-nitrobenzoyl)-4H-furo[2,3-h]chromone
  • 5.5. Synthesis of chromones, annulated with 5-membered heterocycles
  • 5.6. Synthesis of pyrano[2,3-h]chromones
  • 5.7. Synthesis of chromones
  • References.
  • 7.6. Reactivity
  • 7.6.1. Isoprenylation of fluoroxanthone
  • 7.6.2. Synthesis of DDO-6101
  • 7.6.3. CH activation reaction in xanthone
  • 7.6.4. Regioselective methylation of xanthones
  • 7.6.5. Regioselective ring opening of xanthone and further reaction
  • 7.7. Conclusion
  • References
  • Chapter 8: Chemistry of benzo fused chromenones and partially reduced benzo fused chromenones
  • Section A: Chemistry of benzo fused chromenones
  • 8A.1. Introduction
  • 8A.2. Benzo[c]chromene-6-ones
  • 8A.3. Benzo[f]chromen-3-one
  • 8A.4. Benzo[g]chromen-2-ones
  • 8A.5. Benzo [h] chromen-2-one
  • References
  • Section B: Chemistry of partially reduced benzo fused chromenones
  • 8B.1. Introduction
  • 8B.2. Dihydrobenzo[c]chromenone
  • 8B.3. Dihydrobenzo[f]chromenone
  • 8B.4. Dihydrobenzo[g]chromenone
  • 8B.5. Dihydrobenzo[h]chromenone
  • 8B.6. Chemical reactivity of partially reduced benzochromenones
  • 8B.6.1. Chemical reactivity of partially reduced benzochromenones towards C-C bond formation reactions
  • 8B.6.2. Chemical reactivity of partially reduced benzochromenones towards C-X bond formation reactions
  • References
  • Chapter 9: Miscellaneous fused pyranone systems
  • 9.1. 2H,5H-Thiochromeno[4,3-b]pyran-2-ones
  • 9.2. 5,6-Dihydro-2H-benzo[b]pyrano[2,3-d]oxepin-2-one
  • 9.3. 5,6-Dihydro-2H-naphtho[2,3-b]pyrano[2,3-d]oxepin-2-one
  • 9.4. 8H-Acenaphtho[1,2-b]pyran-8-one
  • 9.5. Pyrano[3,4-c]pyran-1,8-dione
  • 9.6. 6,7-Dihdrobenzo[6,7]cyclohepta[1,2-b]pyran-2(5H)-one
  • References
  • Chapter 10: Importance of fused-pyranones in medicine and material science
  • 10.1. Medicinal importance of fused-pyranones
  • 10.1.1. Anticancer activities of fused-pyranones
  • 10.1.2. Anti-coagulant properties of fused-pyranones
  • 10.1.3. Antimicrobial properties of fused-pyranones
  • 10.1.4. Antiviral properties of fused pyranones.
  • 10.1.5. Anti-inflammatory properties of fused pyranones
  • 10.1.6. Miscellaneous medicinal properties of fused pyranones
  • 10.2. Application of fused pyranones in material science
  • References
  • Index.