Mass-action law dynamics theory and algorithm for translational and precision medicine informatics /

Provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D,...

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Bibliographic Details
Main Author: Chou, Ting-Chao (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: London ; San Diego, CA : Academic Press, an imprint of Elsevier, [2024]
Edition:First edition.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections this book leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.
Physical Description:1 online resource
Bibliography:Includes bibliographical references and index.
ISBN:9780443288753
0443288755