Recent advances in organometallic chemistry : synthetic, mechanistic and medicinal perspective /

Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry.Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Ansari, Azaj, Kumar, Vinod
Format:	eBook
Language:	English
Published:	Amsterdam : Elsevier, 2024.
Subjects:	Organometallic chemistry. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

5.3.2 Iron-catalyzed C-H activation
5.3.3 Rhodium-catalyzed C-H activation
5.4 Future prospective and scope
5.5 Summary
References
6 Organotransition metal chemistry in asymmetric catalysis mediated by different transition metal N-heterocyclic carbene co...
6.1 Introduction
6.2 Fundamental principles
6.3 Common methods of preparation
6.4 Mechanism involved
6.5 Recent developments with examples
6.6 Applications in emerging fields
6.7 Future prospective and scope
6.8 Summary
6.9 Problems with solutions
6.10 Objective type questions
References
7 Organophosphorus compounds: recent developments and future perspective
7.1 Introduction
7.2 Fundamental principles
7.2.1 Phosphorus-based ligands
7.2.2 Classification of phosphorus-based ligands
7.3 Common methods of preparation
7.3.1 Pincer ligands
7.3.2 Synthesis of pincer complexes
7.3.2.1 C-H bond activation
7.3.3 Oxidative addition to aryl halide bond
7.3.4 Trans-metallation
7.3.5 Trans-cyclometallation
7.4 Classification of pincer complexes
7.4.1 Transition metal chemistry of pincer ligands
7.4.1.1 PCP pincer complexes
7.4.1.2 PNP pincer complexes
7.4.2 Application of tridentate chelating pincer complexes in catalysis
7.4.2.1 Heck cross-coupling reactions
7.4.2.2 Asymmetric allylation of sulfonimines
7.4.2.3 Hydrophosphination reaction
7.4.3 Chiral tridentate chelating pincer complexes
7.4.4 Aminophosphines
7.4.4.1 Cyclodiphosphazanes
7.4.4.2 Cis/trans isomerization
7.4.4.3 Synthesis of cyclodiphosphazanes
7.4.4.4 Reactivity of cyclodiphosphazanes
7.4.4.5 Macrocyclic cyclodiphosphazane derivatives
7.4.5 Phosphacyclophanes
7.5 Summary
7.6 Problems with solutions
7.7 Objective-type questions
References.
8 Synthesis of silicon and germanium organometallic compounds and their applications in catalysis
8.1 Introduction
8.2 Synthesizing of silicon and germanium organometallic compounds
8.2.1 Direct synthesis
8.2.2 Hydrosilylation
8.2.3 Silenes
8.2.4 Silicones, silyl ethers, silanols, siloxanes, and siloxides
8.2.5 Bonding through carbon
8.3 Catalysis
8.4 Future prospective and scope
8.5 Summary
8.6 Problems with solutions
8.7 Objective type questions
References
9 Sensing application of organometallic compounds
9.1 Introduction
9.2 Fundamental principles
9.3 Common methods of preparation
9.4 Mechanism involved
9.4.1 Ligand substitution
9.4.2 Oxidative addition
9.4.3 Concerted track based
9.5 Recent developments with examples
9.6 Applications in emerging fields
9.6.1 Chemical sensor
9.6.2 Gas sensor
9.6.3 Optical sensor
9.6.4 Biochemical sensor
9.7 Future prospective and scope
9.8 Summary
9.9 Problems with solutions
9.10 Objective type questions
References
10 Bioorganometallic chemistry: a new horizon on organometallic landscape
10.1 Introduction
10.2 Shift from platinum metal based therapeutics to other bio-compatible less toxic nonplatinum complexes
10.2.1 Anticancerous properties of iron complexes
10.2.2 Anticancer properties of copper complexes
10.2.3 Anticancer properties of ruthenium complexes
10.2.3.1 Substitution modulated anticancer activity of Half-sandwich ruthenium (II) complexes with heterocyclic ancillary l...
10.2.4 Anticancer properties of gold complexes
10.2.5 Anticancer properties of rhodium and iridium complexes
10.3 Organoselenium compounds as potent chemotherapeutic agents
10.3.1 Inorganic selenium compounds
10.3.2 Organic selenium compounds
10.3.3 Selenocysteine
10.3.4 Selol.
10.3.5 Seleninic acids
10.3.6 Selenophene-based derivatives
10.3.7 1,2-Benzisoselenazole-3[2H]-one derivatives
10.3.8 Analysis of anticancer property of selenium-bearing 4-anilinoquinazoline compounds
10.3.8.1 Anticancer agent
10.3.9 Evaluation of indole chalcone and diarylketone derivatives containing selenium as tubulin polymerization inhibitory ...
10.3.9.1 Effect of diarylketone selenium derivative(compound-36) on the advancement of cell apoptosis
10.3.10 Chemopreventive applications of isoselenocyanate compounds
10.4 Other biological activities of organoselenium compounds
10.4.1 GPx activity
10.4.1.1 Catalytic GPx-like activity of 2,7-dialkoxy-substituted naphthalene-1,8-peri diselenides
10.4.1.2 pH-sensitive organoselenium compounds as pH-responsive glutathione peroxidase mimics
10.4.1.2.1 Mechanistic study
10.4.1.3 Enhanced activity as glutathione peroxidase mimics when benzo[d]isoselenazol-3-ones are combined with sterically h...
10.4.2 Anti-Alzheimer activity
10.4.2.1 Selenyl-dihydrofurans as anti-Alzheimer agents
10.4.2.2 Selenodihydropyrimidinones as potential multi-targeted treatments for Alzheimer's disease
10.4.2.3 AChE inhibitory activity
10.4.3 Cytoprotection
10.4.3.1 Organoselenium antioxidant compounds with cytoprotective effects
10.4.3.2 Bromo substituted diselenide compounds potential to scavenge ROS
10.4.4 Insecticidal activity
10.4.4.1 Selenoethers and their insecticidal activities
10.4.4.2 2,2-Difluoro-1,3-benzoxathioles (selenoles)with insecticidal activities
10.4.4.3 Selenium-containing imidazolium ionic liquids with antibacterial activity
10.4.4.4 Cyclization of Z-selenoenynes by iron(III)-PhSeSePh results in selenophenes with antidepressant-like activity
10.5 Different plausible mechanisms of action for bioorganometallic complexes.