http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Front Cover -- Exosomal RNA -- Exosomal RNA: ROLE IN HUMAN DISEASES AND THERAPY -- Contents -- Contributors -- Preface -- One -- Exosomal RNA-an introduction -- 1 Introduction -- 2 Characteristics of exosomal RNA -- 2.1 Exosomal MiRNAs -- 2.2 Exosomal circular RNAs -- 3 Importance of exosomal RNAs -- 4 Role of exosomal RNAs in different diseases -- 4.1 Cancer diagnosis and prognosis -- 4.2 Autophagy-related disorder -- 4.3 Diabetic and metabolic diseases -- 4.4 Immunological diseases -- 4.5 Neurodegenerative diseases -- 4.6 Aging-related disorder -- 4.7 Cardiovascular diseases
4.8 Renal disease [81] -- 4.9 Bacterial infection diseases -- 4.10 Wound healing and tissue repairing -- 5 Concluding remarks -- References -- Two -- Biogenesis of exosome and exosomal RNA and its isolation and physical characterizations -- 1 Introduction -- 1.1 Biogenesis and release of exosomes -- 1.2 Endosomal sorting complex required for transport and exosomal biogenesis -- 1.3 ESCRT-independent mechanism of exosome biogenesis -- 1.4 MVBs transport to the membrane and release exosomes -- 1.5 Basal composition and cargo -- 1.5.1 Nucleic acids -- 1.5.2 Proteins -- 1.5.3 Lipids
2 Exosome isolation -- 2.1 Ultrafiltration -- 2.2 Ultracentrifugation -- 2.2.1 Differential ultracentrifugation -- 2.2.2 Density gradient ultracentrifugation -- 2.3 Precipitation -- 2.4 Immunoaffinity capture -- 2.5 Size-exclusion chromatography -- 3 Characterization of exosomes -- 3.1 Ultrastructural analysis -- 3.2 Nanoparticle tracking analysis -- 3.2.1 Advantages of NTA -- 3.2.2 Disadvantages of NTA -- 3.3 Atomic force microscopy -- 3.4 Flow cytometry -- 3.5 Western blotting -- 3.6 Other methods -- 3.6.1 Fluid flow fraction -- 3.6.2 Raman spectroscopy -- 4 Conclusion -- References
Three -- Exosomal RNA in cancer progression -- 1 Introduction -- 2 Exosomal RNAs in cancer progression -- 2.1 Gastrointestinal cancer progression -- 2.1.1 Gastric cancer progression -- 2.1.2 Pancreatic cancer progression -- 2.1.3 Hepatocellular carcinoma progression -- 2.1.4 Colorectal cancer progression -- 2.2 Blood cancer progression -- 2.3 Lung cancer progression -- 2.4 Breast cancer progression -- 2.5 Glioma progression -- 2.6 Thyroid cancer progression -- 2.7 Cervical cancer progression -- 2.8 Prostate cancer progression -- 2.9 Ovarian cancer progression -- 3 Conclusion -- References
Further reading -- Four -- Exosomal RNA as a biomarker in cancer diagnostics and therapy -- 1 Introduction -- 2 Exosomal RNA as a biomarker for diagnosis and therapy outcome of common tumor types -- 2.1 Brain cancer -- 2.2 Oral cancer -- 2.3 Breast cancer -- 2.4 Lung cancer -- 2.5 Skin cancer -- 2.6 Liver cancer -- 2.7 Gastric cancer -- 2.8 Pancreatic cancer -- 2.9 Prostate cancer -- 2.10 Gynecological cancers -- 2.11 Colorectal cancer -- 2.12 Hematological cancers -- 3 Conclusion -- References -- Five -- Exosomal RNA and autophagy -- 1 Introduction -- 2 Exosome biogenesis and composition
edited by Debalina Bhattacharya, Mainak Mukhopadhyay, Kursad Turksen.
Includes bibliographical references and index.
Exosome Multienzyme Ribonuclease Complex