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Glycosphingolipids in the central nervous system : diversity in structure, metabolism, distribution, and function /

Bibliographic Details
Main Author: Guo, Zhongwu (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2024]
Subjects:
Glycosphingolipids.
Central nervous system.
Glycosphingolipids
Central Nervous System
Glycosphingolipides.
Système nerveux central.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Glycosphingolipids in the Central Nervous System
  • Copyright Page
  • Contents
  • Preface
  • 1 Introduction to carbohydrates and glycoconjugates
  • 1.1 Carbohydrates
  • 1.1.1 Monosaccharides
  • 1.1.2 Oligosaccharides
  • 1.1.3 Polysaccharides
  • 1.1.4 Glycosyltransferases involved in carbohydrate biosynthesis
  • 1.1.5 Glycosidases involved in carbohydrate degradation
  • 1.2 Glycoconjugates
  • 1.2.1 Glycoproteins
  • 1.2.2 Proteoglycans
  • 1.2.3 Glycolipids
  • 1.3 Major glycolipids in animals
  • 1.3.1 Glycosylphosphatidylinositol anchors
  • 1.3.2 Glycosphingolipids
  • 1.4 Summary
  • Acknowledgments
  • Abbreviations
  • References
  • 2 Glycosphingolipid structure and metabolism
  • 2.1 Introduction
  • 2.2 Glycosphingolipid structure
  • 2.2.1 Classification of glycosphingolipids
  • 2.2.2 Structural diversity of the glycan
  • 2.2.3 Functionalization of the glycan
  • 2.2.4 Structural diversity of the lipid
  • 2.3 Glycosphingolipid biosynthesis
  • 2.4 Glycosphingolipid catabolism
  • 2.5 Regulation of glycosphingolipid metabolism
  • 2.6 Summary
  • Acknowledgments
  • Abbreviations
  • References
  • 3 Analysis of glycosphingolipids in the central nervous system
  • 3.1 Introduction
  • 3.2 Extraction of biological glycosphingolipids
  • 3.3 Profiling glycosphingolipids by thin-layer chromatography
  • 3.4 Profiling glycosphingolipids by mass spectrometry
  • 3.4.1 General methods for mass spectrometry analysis of glycosphingolipids
  • 3.4.2 Mass spectra of glycosphingolipids: fragment ions, nomenclature, and interpretation
  • 3.4.3 Profiling glycosphingolipids by thin-layer chromatography-mass spectrometry
  • 3.4.4 Profiling glycosphingolipids by liquid chromatography-mass spectrometry
  • 3.4.5 Profiling glycosphingolipids by capillary electrophoresis-mass spectrometry
  • 3.4.6 Profiling glycosphingolipids by microfluidics-mass spectrometry
  • 3.4.7 Profiling glycosphingolipids by ion mobility spectrometry-mass spectrometry
  • 3.4.8 Profiling spatial glycosphingolipids in tissues by mass spectrometry imaging
  • 3.5 Structural study of glycosphingolipids by nuclear magnetic resonance spectroscopy
  • 3.6 Summary
  • Acknowledgments
  • Abbreviations
  • References
  • 4 Glycosphingolipid distribution in the central nervous system
  • 4.1 Introduction
  • 4.2 Glycosphingolipid distribution in human brain
  • 4.3 Glycosphingolipid distribution in rat brain
  • 4.4 Glycosphingolipid distribution in mouse brain
  • 4.5 Glycosphingolipid distribution in the brain of other animals
  • 4.6 Lipid structures of glycosphingolipids in the central nervous system
  • 4.7 Age-related changes in the composition of central nervous system glycosphingolipids
  • 4.8 Summary
  • Acknowledgments
  • Abbreviations
  • References
  • 5 Functions of glycosphingolipids in the central nervous system
  • 5.1 Introduction
  • 5.2 Glycosphingolipids in brain development
  • 5.3 Glycosphingolipids in neural differentiation
  • 5.4 Glycosphingolipids in cell signaling