Glycosphingolipids in the central nervous system : diversity in structure, metabolism, distribution, and function /

Bibliographic Details
Main Author: Guo, Zhongwu (Author)
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Published: Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2024]
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 1 0 |a Glycosphingolipids in the central nervous system :  |b diversity in structure, metabolism, distribution, and function /  |c Zhongwu Gou. 
264 1 |a Amsterdam, Netherlands ;  |a Cambridge, MA :  |b Elsevier,  |c [2024] 
300 |a 1 online resource (x, 443 pages) :  |b illustrations (chiefly color) 
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504 |a Includes bibliographical references and index. 
505 0 |a Front Cover -- Glycosphingolipids in the Central Nervous System -- Copyright Page -- Contents -- Preface -- 1 Introduction to carbohydrates and glycoconjugates -- 1.1 Carbohydrates -- 1.1.1 Monosaccharides -- 1.1.2 Oligosaccharides -- 1.1.3 Polysaccharides -- 1.1.4 Glycosyltransferases involved in carbohydrate biosynthesis -- 1.1.5 Glycosidases involved in carbohydrate degradation -- 1.2 Glycoconjugates -- 1.2.1 Glycoproteins -- 1.2.2 Proteoglycans -- 1.2.3 Glycolipids -- 1.3 Major glycolipids in animals -- 1.3.1 Glycosylphosphatidylinositol anchors -- 1.3.2 Glycosphingolipids -- 1.4 Summary 
505 8 |a Acknowledgments -- Abbreviations -- References -- 2 Glycosphingolipid structure and metabolism -- 2.1 Introduction -- 2.2 Glycosphingolipid structure -- 2.2.1 Classification of glycosphingolipids -- 2.2.2 Structural diversity of the glycan -- 2.2.3 Functionalization of the glycan -- 2.2.4 Structural diversity of the lipid -- 2.3 Glycosphingolipid biosynthesis -- 2.4 Glycosphingolipid catabolism -- 2.5 Regulation of glycosphingolipid metabolism -- 2.6 Summary -- Acknowledgments -- Abbreviations -- References -- 3 Analysis of glycosphingolipids in the central nervous system -- 3.1 Introduction 
505 8 |a 3.2 Extraction of biological glycosphingolipids -- 3.3 Profiling glycosphingolipids by thin-layer chromatography -- 3.4 Profiling glycosphingolipids by mass spectrometry -- 3.4.1 General methods for mass spectrometry analysis of glycosphingolipids -- 3.4.2 Mass spectra of glycosphingolipids: fragment ions, nomenclature, and interpretation -- 3.4.3 Profiling glycosphingolipids by thin-layer chromatography-mass spectrometry -- 3.4.4 Profiling glycosphingolipids by liquid chromatography-mass spectrometry -- 3.4.5 Profiling glycosphingolipids by capillary electrophoresis-mass spectrometry 
505 8 |a 3.4.6 Profiling glycosphingolipids by microfluidics-mass spectrometry -- 3.4.7 Profiling glycosphingolipids by ion mobility spectrometry-mass spectrometry -- 3.4.8 Profiling spatial glycosphingolipids in tissues by mass spectrometry imaging -- 3.5 Structural study of glycosphingolipids by nuclear magnetic resonance spectroscopy -- 3.6 Summary -- Acknowledgments -- Abbreviations -- References -- 4 Glycosphingolipid distribution in the central nervous system -- 4.1 Introduction -- 4.2 Glycosphingolipid distribution in human brain -- 4.3 Glycosphingolipid distribution in rat brain 
505 8 |a 4.4 Glycosphingolipid distribution in mouse brain -- 4.5 Glycosphingolipid distribution in the brain of other animals -- 4.6 Lipid structures of glycosphingolipids in the central nervous system -- 4.7 Age-related changes in the composition of central nervous system glycosphingolipids -- 4.8 Summary -- Acknowledgments -- Abbreviations -- References -- 5 Functions of glycosphingolipids in the central nervous system -- 5.1 Introduction -- 5.2 Glycosphingolipids in brain development -- 5.3 Glycosphingolipids in neural differentiation -- 5.4 Glycosphingolipids in cell signaling 
500 |a 5.5 Glycosphingolipids in neural protection 
588 |a Description based on online resource; title from digital title page (viewed on March 22, 2024). 
650 0 |a Glycosphingolipids. 
650 0 |a Central nervous system. 
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