Semiconducting polymer materials for biosensing applications /

This book provides a comprehensive overview of polymer materials and their applications in biosensing, edited by leading experts from various institutions. It explores advances in polymer-based biosensors, highlighting strategies involving conducting polymeric platforms and polymer dots for fluoresc...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Cheong, Kuan Yew (Editor), Fraga, Mariana Amorim (Editor), Sonar, Prashant (Editor), Pessoa, Rodrigo (Editor), Casanova-Moreno, Jannu (Editor)
Format:	eBook
Language:	English
Published:	Oxford : Woodhead Publishing, 2024.
Subjects:	Semiconductors. Polymers. Biosensors > Materials. Semi-conducteurs. Polymères. Biocapteurs > Matériaux. semiconductor. polymers. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Front Cover
Semiconducting Polymer Materials for Biosensing Applications
Semiconducting Polymer Materials for Biosensing Applications
Copyright
Contents
List of contributors
Preface
One
Introduction and background
1
Advances in semiconducting polymer materials for biosensing applications
1.1 Introduction
1.2 Biosensing strategies based on conducting polymeric platforms
1.2.1 Modern techniques of semiconducting polymer-based transducing layers
1.2.2 Trends in nucleic acid biosensors based on semiconducting polymers
1.2.3 Biotechnological applications of semiconducting polymer-lectin sensor systems
1.2.4 Semiconducting polymer technology
1.3 Conclusions and future perspectives
References
2
Semiconducting polymer dots for fluorescence biosensing and imaging
2.1 Introduction
2.1.1 Fluorescent probes
2.1.2 Semiconducting polymers and semiconducting polymer dots
2.1.3 Preparation of semiconducting polymer dots
2.2 Biosensing and imaging applications of polymer dots
2.2.1 Ratiometric biosensing and bioimaging
2.2.2 Biosensing and bioimaging based on two-photon polymer dots
2.3 Novel applications and future directions of semiconducting polymer dots
2.3.1 Near-infrared II region polymer dots for bioimaging
2.3.2 Three-photon excited polymer dots
2.4 Conclusion and outlook
Acknowledgments
References
3
Semiconducting polymers for a new generation of electrochemical sensors
3.1 Introduction
3.2 Electrochemical sensors based on organic electrochemical transistors
3.2.1 Principles of operation of organic electrochemical transistors
3.2.2 Organic electrochemical transistors as ionic sensors
3.2.3 Organic electrochemical transistors as metabolite sensors
3.2.4 Organic electrochemical transistors as DNA sensors.
5.7.5 DPP-based block copolymer
5.8 Summary and future trend
Acknowledgments
References
6
Low-temperature atomic layer deposition as an advanced fabrication technique of semiconductor polymer materials
6.1 Introduction
6.2 Atomic layer deposition thin film growth mechanisms and its advantages and disadvantages
6.2.1 Advantages of atomic layer deposition
6.2.2 Disadvantages of atomic layer deposition
6.3 Atomic layer deposition thin film growth mechanism on polymers
6.3.1 Types of polymeric surface
6.3.2 Infiltration of atomic layer deposition reactants into subsurface of polymers
6.4 Applications of atomic layer deposition on polymer materials in development of sensors and other devices
6.5 Final remarks
Acknowledgments
References
7
Conjugated and nonconjugated redox polymers for immobilization and charge transfer in oxidoreductase-based electrochemi ...
7.1 Introduction
7.2 Charge transport mechanisms
7.2.1 Charge transport in conjugated redox polymers
7.2.2 Charge transport in nonconjugated redox polymers
7.2.3 Immobilization and deposition of enzymes and redox polymers on electrode surfaces
7.2.4 Covalent bonding
7.2.5 Noncovalent interactions
7.2.6 Mechanical immobilization
7.3 Sensing mechanisms
7.4 Practical examples in biosensing
7.4.1 Oxidases
7.4.2 Dehydrogenases
7.4.3 Peroxidases
7.5 Conclusion and perspectives
References
8
Semiconductor multimaterial optical fibers for biomedical applications
8.1 Introduction
8.2 Materials for semiconductor multimaterial optical fibers
8.2.1 Silicon materials
8.2.2 Germanium materials
8.2.3 Selenium and tellurium materials
8.2.4 Compound semiconductor materials
8.2.5 Cladding materials
8.3 Multimaterial optical fiber fabrication
8.3.1 Thermal drawing.
8.3.1.1 Preform fabrication
8.3.1.2 Thermal drawing
8.3.2 Molten core method
8.3.3 High-pressure chemical vapor deposition
8.3.4 Post-processing
8.3.4.1 Thermal annealing
8.3.4.2 Rapid photothermal processing
8.3.4.3 Laser treatment
8.3.4.4 Interfacial modifier
8.4 Biomedical applications
8.4.1 Wearable thermoelectric sensor for inflammation monitoring
8.4.2 In vivo optoelectronic sensor for lesion detection
8.4.3 In vitro chemical sensors to detect respiratory disorders
8.4.4 Omnidirectional dielectric mirror fibers for neural surgery
8.5 Discussion
8.6 Conclusion
References
9
Fundamentals and current status of polymeric piezoresistive cantilever technology applied on biosensors
9.1 Introduction
9.2 Piezoresistive properties of polymeric materials
9.2.1 Piezoresistive effect in semiconductors
9.2.2 Piezoresistivity and the quantum theory
9.2.3 Piezoresistive effect in polymeric materials
9.3 Microfabrication and nanofabrication processes and techniques for cantilevers
9.3.1 Photolithography
9.3.2 Thin film deposition
9.3.3 Etching
9.3.3.1 Plasma-assisted etching
9.3.4 Microfabrication steps of microcantilevers on silicon and SU-8 polymer
9.4 Biosensors based on polymeric cantilevers
9.5 Final remarks
Acknowledgments
References
Three
Applications of polymer-based biosensors
10
Overview of clinical applications of biosensors
10.1 Introduction
10.2 Types of biosensors
10.3 Important parameters in biosensors
10.3.1 Sensitivity
10.3.2 Dynamic range
10.3.3 Limit of detection
10.3.4 Response and recovery time
10.3.5 Selectivity
10.3.6 Real sample analysis
10.4 Functionalization of various types of nanomaterials for constructing biosensors
10.4.1 Metal nanoparticles
10.4.2 Carbon nanomaterials (carbon nanotubes).
10.4.3 Silicon nanowires
10.4.4 Conductive polymeric nanomaterials
10.4.5 Semiconducting polymer nanomaterials
10.5 Biofunctionalization of sensor
10.5.1 Enzymes
10.5.2 Antibodies
10.5.3 Deoxyribonucleic acid
10.6 Clinical applications of biosensors
10.6.1 In vivo monitoring
10.6.2 In vitro monitoring
10.7 Significance of biosensors in clinical applications
10.8 Types of medical biosensors
10.8.1 Optical medical biosensors
10.8.2 Electrochemical medical biosensors
10.9 Application of biosensors in medical and clinical fields
10.9.1 Biosensors for cancer diagnosis
10.9.2 Biosensors for diagnosis of other diseases
10.10 Conclusion
References
Further readings
11
Electrogeneration and characterization of poly(2-aminobenzamide) with application in the development of an electrochem ...
11.1 Introduction
11.2 Experimental
11.2.1 Electropolymerization and characterization of 2-aminobenzamide
11.2.2 Electrochemical studies for a mechanism proposal
11.2.3 Probe immobilization
11.2.4 Sample handling and detection
11.2.5 Optimization studies
11.2.6 Sensibility, selectivity, reproducibility, and stability studies
11.3 Results and discussion
11.3.1 Screen-printed carbon electrode/poly(2-aminobenzamide) electrogeneration and electrochemical characterization
11.3.2 Obtention of number of protons and electrons in electrochemical oxidation of 2-aminobenzamide
11.3.3 ATR-FTIR study and proposed mechanism for poly(2-aminobenzamide)
11.3.4 Optimization studies of transducer construction and genosensor response
11.3.5 Sensibility, reproducibility, and stability studies
11.3.6 Detection of severe acute respiratory syndrome coronavirus 2 in clinical samples
11.4 Conclusions
Acknowledgments
References.
12
Electrochemical biosensors for determination of tumor biomarkers.