Microbiota brain axis : a neuroscience primer /
Microbiota Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance o...
| Main Authors: | , |
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| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
London :
Academic Press,
2024.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- Microbiota Brain Axis
- Microbiota Brain Axis
- Copyright
- Contents
- About the authors
- Foreword
- 1
- The gut-brain axis
- References
- 2
- What is a healthy microbiome?
- Introduction
- Microbiota composition and function in healthy individuals
- Microbiota diversity across body sites in healthy individuals
- Interindividual differences in bacterial taxa in healthy individuals
- Sex influences microbiota composition and function
- Age influences microbiota composition and function
- Diet influences microbiota composition and function
- Key taxa in the healthy microbiome
- Faecalibacterium prausnitzii
- Akkermansia muciniphila
- Bacteroides
- Prevotella
- Future directions
- References
- 3
- Gene-environment factors influence microbiota composition, diversity, and function
- Introduction
- Animal models
- Human studies
- Future directions
- References
- 4
- Microbiota to brain communication
- Introduction
- The vagus nerve in microbiota to brain communication
- The enteric nervous system in microbiota to brain communication
- The immune system in microbiota to brain communication
- Neuroendocrine signaling in microbiota to brain communication
- Microbial metabolites in microbiota to brain communication
- Microbial regulation of tryptophan metabolism in microbiota to brain communication
- Microbial microvesicles in microbiota to brain communication
- Conclusions, perspectives, and future directions
- References
- 5
- Microbiota influence behavior-Work in animal models
- Overview
- Behavior in germ-free mice
- Antibiotic-related changes in microbiota influence behavior
- The impact of stress on microbiota and behavior
- The impact of diet on microbiota and behavior
- Fecal matter transplantation alters behavior in recipient
- Future directions
- References.
- 6
- Microbiota influence brain systems-Work in animal models
- Introduction
- Neuroimmune signaling
- Neurotransmission
- Neural plasticity
- Future directions
- References
- 7
- Microbiota in neurodevelopmental disorders
- Introduction
- Microbiota to brain communication in neurodevelopment
- Microbiota during pregnancy
- Stress and the postnatal microbiota
- C-section
- Preterm
- Antibiotics
- Mode of feeding
- General
- Microbiota in neurodevelopmental disorders
- Conclusions, perspectives, and future directions
- References
- 8
- Microbiota in psychiatry
- Introduction
- Microbes and mood in healthy people
- Microbes in mood and anxiety disorders
- Major depressive disorder
- Bipolar disorder
- Anxiety disorder
- Schizophrenia
- Future directions
- References
- 9
- Microbiota-brain interactions in aging and neurodegeneration
- Introduction
- The aging gut microbiome: focus on health
- Unhealthy aging and the gut microbiome
- Aging and the gut-brain axis
- Microbiome and Parkinson's disease
- Microbiome and Alzheimer's disease
- Other neurodegenerative disorders: ALS/MS/Huntington's
- Microbiome and aging: longevity in model organisms
- Microbiome and aging: turning back the clock in preclinical models
- Conclusions, perspectives, and future directions
- References
- 10
- Pharmacological treatments and the microbiome-Antibiotics and nonantibiotic drugs
- Introduction
- Antibiotics impact the microbiome and the microbiota-brain axis
- Exposure to antibiotics early in life-Animal studies
- Exposure to antibiotics early in life-Clinical studies
- Exposure in adolescence and adulthood
- The impact of nonantibiotic drugs on microbiota
- Future directions
- References
- 11
- Microbial-related treatments
- Introduction
- Probiotics
- Prebiotics
- Synbiotics
- Postbiotics
- Fermented foods and diet.
- Fecal microbiota transplantation
- Antibiotics
- Conclusions, perspectives, and future directions
- References
- 12
- Microbiota-related biomarkers for precision medicine and drug discovery
- Introduction
- Translational science
- Microbiome biomarkers for precision health
- Where to next?
- References
- Abbreviations
- Index
- Back Cover.