Semisynthesis of bioactive compounds and their biological activities /

Bibliographic Details
Main Author:	Majhi, Sasadhar
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Manickam, Sivakumar
Format:	eBook
Language:	English
Published:	[S.l.] : Elsevier, 2023.
Subjects:	Bioactive compounds > Synthesis. Bioactive compounds > Physiological effect. Composés bioactifs > Synthèse. Composés bioactifs > Effets physiologiques. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Front Cover
Front Matter
SEMISYNTHESIS OF BIOACTIVE COMPOUNDS AND THEIR BIOLOGICAL ACTIVITIES
Copyright
Contents
One
Preliminary concept of semisynthesis and its importance
1.1 Introduction
1.1.1 Concept of semisynthesis
1.1.2 Why do we need semisynthesis?
1.1.3 Recent advances in the potential applications of semisynthetic derivatives
1.1.4 Relationship between semisynthesis and drug delivery
References
Two
Semisynthesis of antibiotics
2.1 Current antibiotic resistance mechanism
2.2 Chemical derivatization of antibiotics
2.2.1 Semisynthesis of platencin thioether derivatives
2.2.2 Semisynthesis of dialkylresorcinol derivatives
2.2.3 Semisynthesis of unguinol derivatives
2.2.4 Semisynthesis of arsinothricin
2.2.5 Semisynthesis of fidaxomicin derivatives
2.2.6 Semisynthesis of amidochelocardin derivatives
2.2.7 Semisynthesis of nidulin derivatives
2.2.8 Semisynthesis of teicoplanin derivatives
2.2.9 Semisynthesis of platensimycin derivatives
2.2.10 Semisynthesis of glycopeptides
2.2.11 Semisynthesis of lipopeptides
2.2.12 Semisynthesis of caprazene derivatives
2.3 Recent advances in the clinical applications of antibiotics and their analogs
References
Three
Semisynthesis of alkaloids
3.1 Function of plant alkaloids on human health
3.1.1 Anticancer activity of plant alkaloids
3.1.2 Antimicrobial activity of plant alkaloids
3.2 Semisynthetic modification of alkaloids
3.2.1 Semisynthesis of apetalrine B
3.2.2 Semisynthesis of promising derivatives of the verticillin class of natural products
3.2.3 Semisynthesis of promising derivatives of rutaecarpine and evodiamine
3.2.4 Semisynthesis of (+)- and (−)-spondomine and stereoisomers
3.2.5 Semisynthesis of esters of galanthamine, 3-O-methylpancracine, vittatine, and maritidine
3.2.6 Semisynthesis of brevicanines A and B
3.2.7 Semisynthesis of 15-chloro-18-oximinoether derivatives
3.2.8 Semisynthesis of 2-epi-narciclasine
3.2.9 Semisynthesis of acetylated makaluvamines
3.2.10 Semisynthesis of the analogs of maclekarpine E
3.2.11 Semisynthesis of (+)-goniomitine
3.2.12 Semisynthesis of piperine-based hydrazone derivatives
3.2.13 Semisynthesis of lipo-alkaloids
3.2.14 Semisynthesis of oxystemofoline, methoxystemofoline and analogs
3.3 Semisynthesis of bioactive marine alkaloids
3.3.1 Semisynthesis of N12-acetylpseudoceratidine, N12-formylpseudoceratidine, N-methylpseudoceratidine and pseudoceratidine azid ...
3.3.2 Semisynthesis of antitumor drug Ecteinascidin 743 and (−)-Jorumycin
3.3.3 Semisynthesis of monoamines derivative
3.3.4 Semisynthesis of discorhabdins P and U and analogs of discorhabdin C
3.4 Recent progress in semisynthesis and potential applications of semisynthetic alkaloid derivatives
References
Four
Semisynthesis of flavones