Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy /
Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Se...
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| Format: | eBook |
| Language: | English |
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London ; San Diego, CA :
Academic Press, an imprint of Elsevier,
[2024]
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Front Cover
- DRUG-DELIVERY SYSTEMS OF PHYTOCHEMICALS AS THERAPEUTIC STRATEGIES IN CANCER THERAPY
- DRUG-DELIVERY SYSTEMS OF PHYTOCHEMICALS AS THERAPEUTIC STRATEGIES IN CANCER THERAPY
- Copyright
- Dedication
- Contents
- About the authors
- Preface
- Introduction
- 1
- Significance of phytochemicals in cancer therapy
- Introduction
- Current challenges in cancer treatment and management
- Phytodrugs: A historical view
- Natural products
- Nutraceuticals
- Anticancer phytocomponents
- Molecular targets of phytochemicals
- Plants compounds targeting ROS and autophagy for cancer treatment
- Clinical trial of phytochemicals for cancer therapy
- Conclusion and future prospectives
- References
- 2
- Emerging need of delivery systems for plant metabolites
- Introduction
- Novel drug delivery methods
- Patterns of drug delivery
- Drug modifications
- Microenvironmental modifications
- Drug delivery systems
- Novel drug delivery systems for plants metabolites
- Benefits of drug delivery system (Pagar &
- Khandbahale, 2019)
- Conclusion and future prospectives
- References
- 3
- Phytosome: A promising drug delivery system for cancer therapy
- Introduction
- Principle for synthesis of phytosomes
- Composition of phytosomes
- Phospholipids
- Solvent for phytosome
- Stoichiometric ratio of phytoactive components and phospholipid
- Anticancer activity of phytosomes-formulated phytochemicals
- Challenges of phytosomal products to commercialization
- Conclusion and future prospect
- References
- 4
- Exosome-based delivery systems for natural compounds in cancer therapy
- Introduction
- Biogenesis of exosomes
- Role of exosomes in cancer
- Modification of exosome-based drug delivery system
- Encapsulation method of therapeutic regimens into exosome
- Surface modification of exosomes with therapeutic compounds.
- 8
- Nanotechnology-based delivery system for phytochemicals in cancer therapy
- Introduction
- Branches of nanotechnology
- Nanoengineering
- Green nanotechnology
- Wet nanotechnology
- Research breakthrough in nanotechnology for development of anticancer drugs
- Advancement in nanotechnology targeting cancer
- Nanodrug delivery systems of phytochemicals for cancer therapy
- Nanoformulation of phytochemicals for cancer treatments
- Nanocarrier-based codelivery of phytochemicals with conventional drugs for cancer treatment
- Clinical applications
- Conclusions and future perspective
- References
- 9
- Delivery system of phenolic compounds for the treatment of lung cancer
- Introduction
- Biological function of polyphenols in cancer
- Classifications of polyphenols
- Biological functions of polyphenols in cancer
- Bioavailability of phenolic compounds
- Polyphenolics drug delivery systems
- Rutin-loaded drug delivery systems
- Baicalin-loaded drug delivery systems
- Chrysin-loaded drug delivery systems
- Apigenin-loaded drug delivery systems
- Ginkgo biloba extract-loaded drug delivery systems
- Naringenin-loaded drug delivery systems
- Drug delivery
- Nanoparticulate delivery systems
- Pulmonary delivery
- Methyl gallate@ZIF-L hybrid as drug delivery system for lung cancer treatment
- Curcumin-loaded solid lipid nanoparticles (Cur-SLNs) as drug delivery system for the lung cancer therapy
- Conclusion and future perspective
- References
- 10
- Advancement in drug delivery systems of curcumin for cancer chemoprevention
- Introduction
- Drug delivery vehicle for curcumin
- Biodegradable curcumin-loaded magnetic microsphere
- Curcumin loaded mesoporous silica
- Curcumin-loaded carboxymethylpachymaran-coated zein
- Engineered UIO-66 metal-organic complex for delivery of curcumin.
- Microsponges as gastroretentive drug delivery system of curcumin
- Folate attached: curcumin-loaded Fe3O4 nanoparticles
- Curcumin-loaded SNEDDS
- Glycyrrhizic acid micellar hydrogel carriers for delivery of curcumin
- Drug delivery systems for synergistic application of curcumin with anticancer regimens
- Curcumin-piperine-loaded human serum albumin nanoparticles against carcinoma cells
- Drug delivery of curcumin and platinum drugs in polymeric micelles
- Codelivery of etoposide and curcumin for treatment of gastric cancer
- Curcumin-bortezomib-loaded polymeric nanoparticles for carcinoma therapy
- Dual drug delivery system for coadministration of curcumin and 5-fluorouracil
- Codelivery of doxorubicin and curcumin through polypeptide nanocarrier
- Conclusions and future prospective
- References
- 11
- Drug delivery system for saponins in cancer treatments
- Introduction
- Classification of saponins
- Sources of saponins
- Natural sources
- Synthetic sources
- Anticancer event of saponin
- Chemoprevention
- Antiinflammatory
- Cell cycle arrest
- Cytotoxicity impact of saponins
- Apoptosis
- Autophagy
- Metastasis
- Saponin in multidrug-resistant carcinoma
- Drug delivery system for saponins
- Saponin emulsion as drug delivery system
- Saponins as surfactant
- Release of nanofiber membrane loaded with saponin
- Saponin-loaded chitosan nanoparticles
- Saponin-loaded montmorillonite-human serum albumin nanocomposites in cancer therapy
- A novel saponin liposome based on the couplet medicines
- Conclusions and future perspectives
- References
- 12
- Administration of plant-derived terpenoids in cancer management
- Introduction
- Mechanism of action of terpenoids against cancer development
- Monoterpenoids
- Thymol
- Menthol
- Auraptene
- Sesquiterpenoids and sesquiterpene lactones
- Sesquiterpene lactones.
- Dehydrocostus lactone
- Helenalin
- Diterpenoids
- Triptolide
- Crocetin
- Phytol
- Triterpenoids
- Ursolic acid
- Betulinic acid
- Lupeol
- Terpene-based therapeutic deep eutectic systems against colorectal cancer
- Coencapsulation and sustained release of terpenes from injectable PELGE nanoparticles
- The combination of nanomicelles with terpenoids for skin drug delivery
- Development of enhanced drug delivery vehicles for three cannabis-based terpenes
- Patents of some terpenoids as an anticancer compound
- Conclusions and future perspectives
- References
- 13
- Therapeutic role of essential oils in malignancies through drug delivery mechanisms
- Introduction
- Activity of essential oils/their constituents on cancer cell lines
- Anticancer properties of essential oils
- Major issues in clinical use of essential oils
- Effective essential oil delivery in living systems
- Aromatherapy: the roots of a bio-based solution
- Drug delivery strategies impact essential oil activity
- Applications of essential oils in combination with synthetic drug
- Problems of current technology
- Nanoencapsulation approach
- Targeted nanodelivery systems for cancer treatment
- Nanodelivery systems of essential oils for breast cancer
- Nanodelivery systems for lung cancer
- Nanodelivery systems for liver cancer
- Conclusion and future perspectives
- References
- 14
- Development of codelivery systems for phytochemicals and targeted siRNA in treatment of cancer
- Introduction
- Event of siRNA action
- Implication of siRNA in cancer therapy
- Phytochemicals-siRNA codelivery
- Docetaxel-siRNA codelivery
- Paclitaxel-siRNA codelivery
- Etoposide-siRNA codelivery
- Conclusions
- References
- 15
- Future challenges of drug-delivery systems for phytochemicals in cancer management
- Introduction.