Cover Image

Colorectal cancer : disease and advanced drug delivery strategies /

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Prajapati, Bhupendra (Editor), Philip, Anil K. (Editor), Bhattacharya, Sankha (Editor)
Format: eBook
Language:English
Published: London, United Kingdom ; San Diego, CA : Academic Press, an imprint of Elsevier, [2024]
Subjects:
Colon (Anatomy) > Cancer > Diagnosis.
Colon (Anatomy) > Cancer > Treatment.
Rectum > Cancer > Diagnosis.
Rectum > Cancer > Treatment.
Colorectal Neoplasms > diagnosis
Colorectal Neoplasms > therapy
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Colorectal Cancer
  • Copyright Page
  • Dedication
  • Contents
  • List of contributors
  • Preface
  • Acknowledgments
  • 1 Colorectal cancer: understanding of disease
  • 1.1 Introduction
  • 1.2 Understanding of disease: colorectal cancer
  • 1.2.1 Etiology and pathogenesis
  • 1.2.1.1 Environmental factors correlated to the incidence of colorectal cancer
  • 1.2.1.1.1 Dietary fat and meat intake
  • 1.2.1.1.2 Vegetables, fruits, and fibers
  • 1.2.1.1.3 Smoking Cigarette
  • 1.2.1.1.4 Alcohol
  • 1.2.1.2 Genes involved in the prognosis and pathogenesis of colorectal cancer
  • 1.3 Diagnosis for colorectal cancer
  • 1.4 Treatment for colorectal cancer
  • 1.4.1 Endoscopic treatment
  • 1.4.2 Chemotherapy
  • 1.4.3 Radiotherapy
  • 1.4.4 Targeted therapies
  • 1.5 Recent advances in the therapeutic interventions of colorectal cancer
  • 1.6 Conclusion
  • Abbreviations
  • References
  • 2 Impact of the microbiome on colorectal cancer development
  • 2.1 Introduction
  • 2.2 Gut microbiome and colorectal cancer
  • 2.2.1 Induction of inflammation by gut microbiota
  • 2.2.2 Dysbiosis and gut microbiota (functional diversity of gut microbiota)
  • 2.2.3 Bacterial microbiota and colorectal cancer
  • 2.2.4 Viral microbiota and colorectal cancer
  • 2.2.5 Fungal microbiota and colorectal cancer
  • 2.3 Gut microbiota and its derived metabolites
  • 2.4 Host microbiota interactions with genomes and epigenomes
  • 2.4.1 Interactions with the genome
  • 2.4.1.1 Cell cycle regulation
  • 2.4.1.2 DNA damage
  • 2.4.1.3 Genomic instability
  • 2.4.2 Interactions with the epigenome
  • 2.4.2.1 DNA methylation
  • 2.4.2.2 miRNAs
  • 2.4.2.3 Histone modifications
  • 2.5 Linking antibiotic-microbiome: risk and attribution of leaky gut to colorectal cancer
  • 2.6 Intestinal stem cells and colorectal cancer
  • 2.6.1 Intestinal stem cells and their homeostasis
  • 2.6.2 Intestinal stem cells or cancer stem cells markers in colorectal cancer
  • 2.6.3 Pathways regulating ISCs/CSCs in colorectal cancer
  • 2.7 Prognostic or diagnostic microbiome-associated early diagnosis
  • 2.8 Therapeutic impact of the gut microbiome on the efficacy of chemotherapy
  • 2.9 Preventive dietary mediators and their protective potential in colorectal cancer
  • 2.9.1 Dietary fibers
  • 2.9.2 Polyunsaturated fatty acids
  • 2.9.3 Polyphenols
  • 2.9.4 Probiotics