Primary immunodeficiency disorders : a historic and scientific perspective /
Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can m...
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
Oxford, England ; Waltham, Massachusetts :
Academic Press,
2014.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Immunity : from serendipitous observations to science-based speciality
- The discovery of the T- and B- cell compartments
- Evolution of the definition of primary immunodeficiencies
- From immunodeficiency to autoimmunity
- Immunological tests : from the microscope to whole genome analysis
- Primary immunodeficiency in the developing countries
- Jeffrey asked us to "do something"! our journey
- Finally found : the Ataxia-Telangiectasia gene and its function
- Wiskott-Aldrich syndrome : from a fatal hematologic disorder to a curable immunodeficiency
- Neutropenia : more genetic defects than ever expected
- B cell defects : from X-linked to autosomal recessive agammaglobulinemia
- The discovery of the familial hemophagocytosis syndromes
- Chronic granulomatous disease : from a fatal disease to a curable one
- Severe combined immunodeficiency : from discovery to newborn screening
- Severe combined immunodeficiency as diseases of defective cytokine signaling
- The hyper IgM syndromes : a long list of genes and years of discovery
- Unraveling the complement system and its mechanism of action
- DiGeorge syndrome : a serendipitous discovery
- The many faces of the hyper IgE syndrome
- ADA deficiency : the first described genetic defect causing PID
- The Leukocyte adhesion deficiency story
- How common variable immune deficiency has changed over six decades
- From subcutaneous to intravenous immunoglobulin and back
- History of hematopoietic stem cell transplantation
- David's story
- How primary immunodeficiencies have made gene therapy a reality.