Medical image analysis /

Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts.This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains.

Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Frangi, Alejandro F., Prince, Jerry, Sonka, Milan
Format: eBook
Language:English
Published: London : Academic Press, [2024].
Series:The MICCAI Society book series
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover
  • Medical Image Analysis
  • Copyright
  • Section editors
  • Contents
  • Editors
  • Contributors
  • Preface
  • Nomenclature
  • Acknowledgments
  • Part I Introductory topics
  • 1 Medical imaging modalities
  • 1.1 Introduction
  • 1.2 Image quality
  • 1.2.1 Resolution and noise
  • 1.2.2 Comparing image appearance
  • 1.2.3 Task-based assessment
  • 1.3 Modalities and contrast mechanisms
  • 1.3.1 X-ray transmission imaging
  • 1.3.2 Molecular imaging
  • 1.3.3 Optical imaging
  • 1.3.4 Large wavelengths and transversal waves
  • 1.3.5 A historical perspective on medical imaging
  • 1.3.6 Simulating image formation
  • 1.4 Clinical scenarios
  • 1.4.1 Stroke
  • 1.4.2 Oncology
  • 1.4.3 Osteonecrosis
  • 1.5 Exercises
  • References
  • 2 Mathematical preliminaries
  • 2.1 Introduction
  • 2.2 Imaging: definitions, quality and similarity measures
  • 2.3 Vector and matrix theory results
  • 2.3.1 General concepts
  • 2.3.2 Eigenanalysis
  • 2.3.3 Singular value decomposition
  • 2.3.4 Matrix exponential
  • 2.3.4.1 Generalities
  • 2.3.4.2 An example which gives rise to a matrix exponential
  • 2.4 Linear processing and transformed domains
  • 2.4.1 Linear processing. Convolution
  • 2.4.2 Transformed domains
  • 2.4.2.1 1D Fourier transform
  • 2.4.2.2 2D Fourier transform
  • 2.4.2.3 N-dimensional Fourier transform
  • 2.5 Calculus
  • 2.5.1 Derivatives, gradients, and Laplacians
  • 2.5.2 Calculus of variations
  • 2.5.3 Some specific cases
  • 2.5.3.1 Laplace equation
  • 2.5.3.2 Heat (or diffusion) equation
  • 2.5.4 Leibniz rule for interchanging integrals and derivatives
  • 2.6 Notions on shapes
  • 2.6.1 Procrustes matching between two planar shapes
  • 2.6.2 Mean shape
  • 2.6.3 Procrustes analysis in higher dimensions
  • 2.7 Exercises
  • References
  • 3 Regression and classification
  • 3.1 Introduction
  • Nomenclature
  • 3.1.1 Regression as a minimization problem.
  • 3.1.2 Regression from the statistical angle
  • 3.2 Multidimensional linear regression
  • 3.2.1 Direction of prediction
  • 3.2.2 Risk minimization
  • 3.2.2.1 Gauss-Markov theorem
  • 3.2.3 Measures of fitting and prediction quality
  • 3.2.4 Out-of-sample performance: cross-validation methods
  • 3.2.5 Shrinkage methods
  • 3.2.5.1 Dealing with multicollinearity: ridge regression
  • 3.2.5.2 Dealing with sparsity: the LASSO
  • 3.2.5.3 Other general regularizers
  • 3.3 Treating non-linear problems with linear models
  • 3.3.1 Generalized linear models: transforming y
  • 3.3.1.1 Classification as a regression problem: logistic regression
  • 3.3.2 Feature spaces: transforming X
  • 3.3.2.1 Categorical variables
  • 3.3.2.2 Linearizing non-linear regression: functional bases
  • 3.3.3 Going further
  • 3.4 Exercises
  • References
  • 4 Estimation and inference
  • 4.1 Introduction: what is estimation?
  • 4.2 Sampling distributions
  • 4.2.1 Cumulative distribution function
  • 4.2.2 The Kolmogorov-Smirnov test
  • 4.2.3 Histogram as probability density function estimate
  • 4.2.4 The chi-squared test
  • 4.3 Estimation. Data-based methods
  • 4.3.1 Definition of estimator and criteria for design and performance measurement
  • 4.3.2 A benchmark for unbiased estimators: the Cramer-Rao lower bound
  • 4.3.3 Maximum likelihood estimator
  • 4.3.4 The expectation-maximization method
  • 4.4 A working example
  • 4.5 Estimation. Bayesian methods
  • 4.5.1 Definition of Bayesian estimator and design criteria
  • 4.5.2 Design criteria for Bayesian estimators
  • 4.5.3 Performance measurement
  • 4.5.4 The Gaussian case
  • 4.5.5 Conjugate distribution and conjugate priors
  • 4.5.6 A working example
  • 4.6 Monte Carlo methods
  • 4.6.1 A non-stochastic use of Monte Carlo
  • 4.7 Exercises
  • References
  • Part II Image representation and processing.
  • 5 Image representation and 2D signal processing
  • 5.1 Image representation
  • 5.2 Images as 2D signals
  • 5.2.1 Linear space-invariant systems
  • Properties of 2D convolution
  • 5.2.2 Linear Circular Invariance systems
  • 5.3 Frequency representation of 2D signals
  • 5.3.1 Fourier transform of continuous signals
  • 5.3.2 Discrete-space Fourier transform
  • 5.3.3 2D discrete Fourier transform
  • 5.3.4 Discrete cosine transform
  • 5.4 Image sampling
  • 5.4.1 Introduction
  • 5.4.2 Basics on 2D sampling theory
  • 5.4.2.1 Inexact reconstruction
  • 5.4.3 Nyquist sampling density
  • 5.5 Image interpolation
  • 5.5.1 Typical interpolator kernels
  • 5.5.1.1 Windowed sinc
  • 5.5.1.2 Nearest neighbor interpolation
  • 5.5.1.3 Linear interpolation
  • 5.5.1.4 Cubic interpolation
  • 5.6 Image quantization
  • 5.7 Further reading
  • 5.8 Exercises
  • References
  • 6 Image filtering: enhancement and restoration
  • 6.1 Medical imaging filtering
  • 6.2 Point-to-point operations
  • 6.2.1 Basic operations
  • 6.2.2 Contrast enhancement
  • 6.2.3 Histogram processing
  • Histogram equalization
  • Histogram specification
  • 6.3 Spatial operations
  • 6.3.1 Linear filtering
  • Smoothing filters
  • Highlighting borders and small details
  • 6.3.2 Non-linear filters
  • Median filter
  • Pseudomedian filter
  • 6.4 Operations in the transform domain
  • 6.4.1 Linear filters in the frequency domain
  • 6.4.2 Homomorphic processing
  • 6.5 Model-based filtering: image restoration
  • 6.5.1 Noise models
  • 6.5.2 Point spread function
  • 6.5.3 Image restoration methods
  • 6.6 Further reading
  • 6.7 Exercises
  • References
  • 7 Multiscale and multiresolution analysis
  • 7.1 Introduction
  • 7.2 The image pyramid
  • 7.3 The Gaussian scale-space
  • 7.4 Properties of the Gaussian scale-space
  • 7.4.1 The frequency perspective
  • 7.4.2 The semi-group property
  • 7.4.3 The analytical perspective.
  • 7.4.4 The heat diffusion perspective
  • 7.5 Scale selection
  • 7.5.1 Blob detection
  • 7.5.2 Edge detection
  • 7.6 The scale-space histogram
  • 7.7 Exercises
  • References
  • Part III Medical image segmentation
  • 8 Statistical shape models
  • 8.1 Introduction
  • 8.2 Representing structures with points
  • 8.3 Comparing shapes
  • 8.4 Aligning two shapes
  • 8.5 Aligning a set of shapes
  • 8.5.1 Algorithm for aligning sets of shapes
  • 8.5.2 Example of aligning shapes
  • 8.6 Building shape models
  • 8.6.1 Choosing the number of modes
  • 8.6.2 Examples of shape models
  • 8.6.3 Matching a model to known points
  • 8.7 Statistical models of texture
  • 8.8 Combined models of appearance (shape and texture)
  • 8.9 Image search
  • 8.10 Exhaustive search
  • 8.10.1 Regression voting
  • 8.11 Alternating approaches
  • 8.11.1 Searching for each point
  • 8.11.2 Shape model as regularizer
  • 8.12 Constrained local models
  • 8.12.1 Iteratively updating parameters
  • 8.12.2 Extracting features
  • 8.12.3 Updating parameters
  • 8.13 3D models
  • 8.14 Recapitulation
  • 8.15 Exercises
  • References
  • 9 Segmentation by deformable models
  • 9.1 Introduction
  • 9.2 Boundary evolution
  • 9.2.1 Marker evolution
  • 9.2.2 Level set evolution
  • 9.3 Forces and speed functions
  • 9.3.1 Parametric model forces
  • 9.3.2 Geometric model speed functions
  • 9.3.3 Non-conservative external forces
  • 9.4 Numerical implementation
  • 9.4.1 Parametric model implementation
  • 9.4.2 Geometric model implementation
  • 9.5 Other considerations
  • 9.6 Recapitulation
  • 9.7 Exercises
  • References
  • 10 Graph cut-based segmentation
  • 10.1 Introduction
  • 10.2 Graph theory
  • 10.2.1 What is a graph?
  • 10.2.2 Flow networks, max flow, and min cut
  • 10.3 Modeling image segmentation using Markov random fields
  • 10.4 Energy function, image term, and regularization term
  • 10.4.1 Image term.
  • 10.4.2 Regularization term
  • 10.5 Graph optimization and necessary conditions
  • 10.5.1 Energy minimization and minimum cuts
  • 10.5.2 Necessary conditions
  • 10.5.3 Minimum cut graph construction
  • 10.5.4 Limitations (and solutions)
  • 10.6 Interactive segmentation
  • 10.6.1 Hard constraints and user interaction
  • 10.6.2 Example: coronary arteries in CT angiography
  • 10.7 More than two labels
  • 10.7.1 Move-making algorithm(s)
  • 10.7.2 Ordered labels and convex priors
  • 10.7.3 Optimal surfaces
  • 10.7.4 Example: airways in CT
  • 10.8 Recapitulation
  • 10.9 Exercises
  • References
  • Part IV Medical image registration
  • 11 Points and surface registration
  • 11.1 Introduction
  • 11.2 Points registration
  • 11.2.1 Procrustes analysis for aligning corresponding point sets
  • 11.2.2 Quaternion algorithm for registering two corresponding point sets
  • 11.2.3 Iterative closest point algorithm for general points registration
  • 11.2.4 Thin plate spline for non-rigid alignment of two corresponding point sets
  • 11.3 Surface registration
  • 11.3.1 Surface mesh representation
  • 11.3.2 Surface parameterization
  • 11.3.2.1 Conformal open surface parameterization
  • 11.3.2.2 Area-preserving spherical parameterization
  • 11.3.3 Surface registration strategies
  • 11.3.3.1 SPHARM surface registration
  • 11.3.3.2 Landmark-guided SPHARM surface registration
  • 11.3.3.3 Landmark-guided open surface registration
  • 11.4 Summary
  • 11.5 Exercises
  • References
  • 12 Graph matching and registration
  • 12.1 Introduction
  • 12.2 Graph-based image registration
  • 12.2.1 Graphical model construction
  • 12.2.2 Optimization
  • 12.2.3 Application to lung registration
  • 12.2.4 Conclusion
  • 12.3 Exercises
  • References
  • 13 Parametric volumetric registration
  • 13.1 Introduction to volumetric registration
  • 13.1.1 Definition and applications
  • 13.1.2 VR as energy minimization.